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Biomedical subjects

M Cianfrocca

Publications and source records attributed to M Cianfrocca.

4 recordsLinked to original sources
PubMed2001

Operable breast cancer.

Breast cancer is the most common malignancy among American women. As a result of widespread screening, most patients present with operable breast cancer that is treated with curative intent. It is well established that the appropriate use of adjuvant therapy improves the disease-free and overall survival of patients with breast cancer. Adjuvant systemic therapy options include tamoxifen for hormone receptor-positive patients, and systemic polychemotherapy. It is standard clinical practice to administer adjuvant systemic therapy to patients with node-positive and high-risk, node-negative breast cancer.

Antineoplastic Combined Chemotherapy Protocols↗
PubMed1998

Epidemic Kaposi's sarcoma.

Kaposi's sarcoma (KS) is the most common malignancy associated with human immunodeficiency virus-1 (HIV-1) infection and can result in significant morbidity. The clinical course of KS is quite variable, although for the majority of patients, KS is ultimately a progressive disease requiring systemic therapy. For early indolent KS, local therapies may be appropriate and may provide significant palliation. For patients with more advanced or rapidly progressive disease, systemic therapy is the treatment of choice. Interferon-alfa (Intron A, Roferon-A), with or without antiretroviral agents, is particularly useful for patients with relatively preserved immune function. For patients with symptomatic visceral disease, pulmonary disease, or rapidly progressive cutaneous disease, chemotherapy is the treatment of choice. An increasing number of agents are now available for the treatment of KS. Pathogenesis-based treatment and/or preventive therapies based on the recognized association between KS-associated herpesvirus (KSHV) and KS are likely to be available in the near future.

Disease Outbreaks↗