PubMed Health⌕ Search

Biomedical subjects

M Cocchi

Publications and source records attributed to M Cocchi.

At least 37 records · Page 2Linked to original sources
PubMed1981

Clinical observations on 76 cluster headache cases.

76 cases of cluster headache are reviewed. Besides confirming established notions, the present study calls attention to the following points: (a) the peculiar behaviour of patients during the attacks does not appear explainable in simple terms of reaction to pain; (b) the occurrence of ECG abnormalities during the attacks in addition to bradycardia; (c) the well-known tendency of cluster headache attacks to recur at the same time of day, has in our cases a very high peak at 3 p.m., and (d) when the attacks occur in sleep hours, the time relationship with REM sleep stage is confirmed in our cases which have been recorded at night.

Adolescent↗
PubMed1980

Coenzyme Q10 levels in rat heart of different age.

CoQ10 is intrinsic to human tissues and is a vitamin, according to the basic science of nutrition. It is known that CoQ10, plays a role in the respiratory process, moreover it seems to be involved in the mechanism of blood coagulation. As a vitamin a deficiency of CoQ10 may be related to some disease, that is, first of all, a disease is bioenergetics. It has been demonstrated that during aging, other than a diminution of EFA (and an increase of palmitoleic and eicosatrienoic fatty acids), a decrease of about the 20-30% in the heart CoQ10 levels occurs in the rat. Perhaps these modifications may be intrinsic to the "biochemical" changes of aging.

Aging↗
PubMed1980

Biometabolic effects of different nutrients on embryonal cultures.

It has been valued the effects of different nutrients (glucose, phospholipids and ethanol) on the growth and morphology of chicken embryo cells, cultured in vitro by "pendent drop". Considering that the basal nourishing substratum used in these studies is the best medium that may be supplied to the cultures for the growth of this kind of tissues, the entity of damage induced by different nutrients has been shown. It may be said that the less negative effect is induced by 2.5% ethanol and by the association: "glucose + 2.5% ethanol", that the damage induced by only glucose seems to improve in presence of 2.5% ethanol, that in presence of phospholipids the cells appear all full of big lipid drops (especially in the condition: "phospholipid + ethanol") and that 5% ethanol deeply appears to impair and alter the cultures, as it was been observed in our previous experiences.

Animals↗
PubMed1979

Influence of phospholipids on the respiratory activity of embryonal heart cells cultured in vitro in presence of different ethanol concentrations.

The influence of phospholipids on respiratory activity of embryonal heart cells, trated with certainly harmful concentrations of ethanol, has been discussed. It has been concluded that when the cell is deeply impaired the administration of phospholipids does not seem to have positive effects. In this condition an irreversible morphological alteration has been induced.

Animals↗
PubMed1979

Effect of ethanol on respiratory activity of embryonal tissues.

By estimating the respiratory activity of various chicken embryonal organs we have noted that it was the highest for the kidney tissues and lower and lower for liver, brain and heart tissues. After the addition of ethanol to the culture medium we may conclude that ethanol 2,5% does not substantially alter the cellular respiratory activity, whereas ethanol 5% remarkably appears to inhibit it. In fact for this last condition the heart and kidney fragments, when are transplanted after 48 hours in "pendent drop", result rarely surviving.

Animals↗
PubMed1979

Effect of organ phospholipids on the growth of embryonal tissues cultured in vitro.

With regard to a set of studies about cellular nutrition, the effect of different amounts of phospholipids, extracted from various organs of calf (diencephalon, retina, cerebral cortex and heart), on normal embryonal chicken myocardium cultures has been tested. From the numerous observations we have made it is resulted that phospholipids, particularly at the highest levels, constantly decrease the culture migration velocity and this reduction is remarkably more accentuated in presence of 1.25%(0) heart phospholipids. Moreover in this condition the cells show a change in their morphology and appear all full of big lipid drops, perhaps in consequence of an alteration of the chemical-physical plasmalemma characteristics and a change in the membrane enzyme activities involving lipid metabolism too.

Animals↗
PubMed1979

Effect of a long term oral administration of a hypercholesterolic diet on rat liver substructures.

The effects of high cholesterol diets on ultrastructure morphologic alterations of rat liver have been investigated. It has been verified that these diets induce the biochemical and morphological damage, as well as death in a shorter time than alipidic or sole saturated lipid diets. Moreover it has been established that the anatomic irreversible damage appears at the last stage, just before death.

Animals↗