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Biomedical subjects

M Coles

Publications and source records attributed to M Coles.

10 recordsLinked to original sources

An outbreak of Salmonella saint-paul infection associated with beansprouts.

In March 1988, there was an outbreak of infection by a strain of Salmonella saint-paul with a distinctive antigenic marker. A total of 143 reports were received between 1 March and 7 June. Preliminary investigations suggested that raw beansprouts were a possible source of infection and a case-control study confirmed the association. S. saint-paul of the epidemic type was isolated from samples of beansprouts on retail sale in different cities in the United Kingdom and from mung bean seeds on the premises of the producer who was most strongly associated with cases. In addition, Salmonella virchow PT34 was isolated from samples of raw beansprouts and was subsequently associated with seven cases of infection. Four other serotypes of salmonella were also isolated from beansprouts. On 8 April the public were advised to boil beansprouts for 15 seconds before consumption, and the premises of the one producer associated with many cases were closed. As a result of these actions there was a significant decrease in the number of infections with S. saint-paul.

Adolescent

An unusual case of dermatofibrosarcoma protuberans.

A dermatofibrosarcoma protuberans involving the thumb of a nondominant hand is reported and represents the first case reported in this location. Dermatofibrosarcoma protuberans is a soft tissue neoplasm. It is a slow growing, locally aggressive fibrous tumor that occurs with equal frequency on the chest, abdomen, back, and proximal aspect of the extremities. Only two cases involving the hand are reported in the literature.

Adult

Management of disturbed and aggressive behaviour in psychopaths.

In order to maximize the benefits of a multimodal therapeutic regime, a therapeutic group milieu setting is needed as a catalyst, followed by mandatory community care. Therefore, the treatment of choice for the psychopath seems to be the integrated comprehensive approach on a long term basis. However, should therapy be ineffective, the structure will be maintained while the elapse of time decreases the psychopathic behaviour to a virtual non-existent entity as a result of aging. In either case, society will be protected.

Adolescent