Lamellar ichthyosis of the newborn. A distinct clinical entity: its comparison to the other ichthyosiform erythrodermas.
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Biomedical subjects
Publications and source records attributed to M Conant.
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The authors convened a conference at the University of California, San Francisco, to provide a framework for developing health education programs to reduce high-risk sexual activity associated with the acquired immunodeficiency syndrome (AIDS). Operating on a consensus model, four groups of experts defined the sexual behaviors that place an individual at high risk for AIDS, the principles of health psychology that can be applied to health education programs for reducing high-risk sexual activity among gay men, the health education and media strategies that might be used, and the factors unique to gay men that need to be considered. We hope that these reports will not only provide a foundation for the discussion of health education strategies for reducing the risk of AIDS, but will also prove useful to local, regional, and national organizations in developing such programs.
The authors tested a polyurethane women's condom for permeability to the human immunodeficiency virus (HIV) and cytomegalovirus (CMV) using an artificial intercourse model. They did not detect viral leakage in three trials for each virus. Use of this device, which can be controlled by the woman, may reduce HIV and CMV infection.
The activity of natural (leukocyte) interferon alfa in the treatment of condylomata acuminata was assessed in a randomized, double-blind, placebo-controlled, multicenter trial. Interferon alfa (Alferon N Injection) or placebo was injected into lesions twice weekly for up to eight weeks. Eighty-six patients were given interferon alfa, and 72 were given placebo. Eighty-six percent of interferon alfa-treated patients and 89% of placebo-treated patients had received previous therapy for condylomata acuminata. Side effects, usually flulike symptoms, occurred briefly after the injections; if present, they disappeared before the end of the third week of therapy. Treatment completely eliminated warts in 62% of interferon alfa-treated patients compared with only 21% of placebo-treated patients. Natural interferon alfa given intralesionally is an effective and safe treatment even in patients with recurrent or recalcitrant genital warts.