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Biomedical subjects

M Cone

Publications and source records attributed to M Cone.

4 recordsLinked to original sources

Satisfaction with a new model of professional practice in critical care.

Although only a moderately severe general nursing shortage exists at this time, the shortage of critical care nurses remains severe. Innovative administrators across the country are trying new professional practice models aimed at maximizing autonomy and freeing nurses from mundane tasks with the hopes of retaining experienced clinicians. We implemented a professional practice model in which unlicensed assistive personnel were trained to assist registered nurses in patient care. Monies saved by increasing nurse-patient ratios were distributed to staff nurses. Acuity-based staffing was maintained and professional practice encouraged through self-scheduling and elimination of hierarchical relationships. Satisfaction among nurses working in the program increased in terms of coworkers and supervision. Patient satisfaction with the quality of care provided did not change during the course of the program. Data from interviews demonstrated that staff were satisfied with the quality of care provided by the assistants, but the changes in the staffing ratios coupled with the increased responsibility for overseeing the assistants caused stress in the nurses. We conclude that a professional practice model in which critical care assistants are added to the work force is a viable option, but creative methods of addressing the stress of increased workload are needed.

Critical Care↗

Cardiopulmonary support in the intensive care unit.

The cardiopulmonary support system is an extracorporeal device that allows for rapid cardiopulmonary support of the critically ill patient in the intensive care unit. It provides immediate and complete support of cardiac and pulmonary functions to maintain perfusion to vital organs in patients who are severely physiologically compromised (eg, in cardiogenic shock, adult respiratory distress syndrome or pulmonary edema). Successful cardiopulmonary support requires systemic anticoagulation, percutaneous venous and arterial cannulation and careful monitoring by the critical care team to maintain adequate tissue perfusion and oxygenation. Although patient mortality can occur secondary to bleeding, embolism or sepsis, this technique provides life-sustaining circulatory and respiratory support until definitive treatment can be initiated.

Anticoagulants↗

Activities of the International Federation of Pharmaceutical Manufacturers Associations in world health.

The IFPMA represents 51 member associations of national pharmaceutical manufacturers throughout the world. It has developed several programs to interface and communicate with the World Health Organisation (WHO) programmes especially in regard to its activities in developing countries. Examples of collaboration with WHO are the IFPMA Training Scheme in Quality Control run jointly with the Pharmaceuticals Unit of the WHO. The IFPMA has developed a Code of Pharmaceutical Marketing Practices. It contributes to the health of both the developed and developing world through industry research, development and production of new and improved medicines. IFPMA publications provide important technical information for the global pharmaceutical industry and deal with the important issues of rational drug use in the developing world.

Drug Industry↗

Computer-controlled laser ablation: a convenient and versatile tool for micropatterning biofunctional synthetic surfaces for applications in biosensing and tissue engineering.

This paper describes laser-based methods for preparing micropatterns of bioactive molecular species in self-assembled monolayers (SAMs) and micropatterns of proteins and other biological molecules immobilized on solid substrates. Applications of these micropatterned surfaces in multianalyte biosensing and tissue engineering are emphasized. The focus of the paper is on the use of a computer-controlled laser ablation system comprising a research-grade inverted optical microscope, a pulsed nitrogen-pumped dye laser emitting at 390 nm, a programmable sample stage, and the computerized control system. The laser system can be implemented in a typical biosensor or tissue culture laboratory to enable the facile and reproducible fabrication of micropatterned surfaces by several methods. Various methods for patterning are discussed with examples given and emphasis placed on (1) laser ablation in the fabrication of photolithography masks, (2) electrochemical patterning of SAMs, and (3) laser desorption of SAMs. The relative merits of each technique are discussed with respect to application in fabrication of active surfaces for biosensing and tissue culture applications.

Biosensing Techniques↗