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Biomedical subjects

M Corcos

Publications and source records attributed to M Corcos.

8 recordsLinked to original sources
PubMed1996

Therapeutical management of depression during adolescence.

Our model of reference remains essentially the psychoanalytic theory of psychic functioning which has permitted us to have a general outlook on the individual: taking into account the genetic and biological aspects of mental functioning, cognitive capacities, requirements concerning learning, as well as the role of affectivity such as is organized through interactions with the environment throughout the patient's life. We suggest that the therapeutical management of depression in adolescence is related to the psychopathology of the patient, especially when there are narcissistic dimensions.

Adolescent↗
PubMedDate not supplied

[Pharmacologic treatment of bulimia].

The rationale for pharmacological treatment of bulimia nervosa is summarized and a review of controlled therapeutic trials shows contradictory results. A number of antidepressant agents (tricyclics: imipramine, desipramine, amitriptyline; IMAO: phenelzine, isocarboxazide; trazodone; fluoxetine) appear more effective than placebo in double-blind controlled trials of 6 to 16 weeks. In similar studies, other antidepressants (mianserine, fluvoxamine) are ineffective. Improvement reported is often incomplete and the low percentage of patients totally abstinent at the end of treatment appears of poor pronostic value for long-term outcome. Methodological limitations of existing studies are discussed, and some psychopathological factors to consider in the assessment of therapeutic response are proposed.

Antidepressive Agents↗
PubMedDate not supplied

[Manic-depressive psychoses in adolescence. Influence of life change events. Study of family dynamics].

A sample of 38 adolescents hospitalized for a major depressive episode melancholic type or a manic episode during the course of a bipolar disorder (according to the DSM III-R Criteria) was examined with particular emphasis on precipating life events and family relationships. Psychosocial stressors in the year preceding onset of the affective disorder were found in a very high proportion of cases (about 80%). Stressors are most often severe. All of these stressors have to do with loss or threat of loss, particularly the most frequent one: the sentimental failure. Analyzing results of a familial dynamic questionnaire, we showed in the MDD sample the prevalence of two psychopathological index: maternal rejection, parental dysharmony.

Adolescent↗