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Biomedical subjects

M Corera Sánchez

Publications and source records attributed to M Corera Sánchez.

7 recordsLinked to original sources
PubMed1996

[The role of the day-care nursery and early schooling on the incidence of infectious diseases].

OBJECTIVE: The purpose of this study was to study if early care away from home of infants and young children increases the incidence and severity of infectious disease episodes and to define the age group in which the infection risk is highest. MATERIAL AND METHODS: A prospective cohort study was conducted in three pediatric clinics of a primary health care center. RESULTS: The mean number of infectious disease episodes was 7.2 (< 2 years of age), 6.3 (2-3 years) and 5.05 (> 3 years) in children attending school for the first year and 4.0, 3.1 and 2.7 for children of the same age groups not attending school. For the first year of schooling, the relative risk (RR) and 95% confidence intervals (CI) for some specific diseases, in children between 6-24 months of age were 1.99 (1.03-3.83) for more than two episodes of otitis media and 4.59 (1.97-10.7) for more than three episodes of bronchial asthma. Children between 24 and 36 months of age had RR and CI of 4.63 (1.51-14.8) for more than two episodes of otitis media. CONCLUSION: Infants and small children cared for outside of the home environment have a greater number of acute infectious disease episodes than those cared for at home. The risk is higher during the first year of schooling, particularly in those less than two years of age.

Acute Disease↗
PubMed1992

[Celiac disease and short stature in children].

Celiac disease (CD) is a known cause of short stature and sometimes, this is its only symptom. The aim of this work was to determine the incidence of CD in children with short stature. We studied 178 infants with short stature and with no gastrointestinal symptoms. Serum IgA antigliadin antibodies were determined in all of them. We found a pathological titer in ten of these patients. Peroral intestinal biopsy was performed on these children, with nine showing no alterations and only one having subtotal villus atrophy that was compatible with CD. Therefore, the incidence of CD in this population is about 0.56%, which is much lower than the incidence shown by other authors.

Adolescent↗
PubMed1992

[Nutritional study of children with oncologic diseases].

From October 1989 to June 1990 we have evaluated at diagnosis and after six months of treatment the nutritional status of 21 oncologic patients younger than 14 years. At diagnosis, 14% of the children showed slight malnutrition on anthropometric evaluation, although there were biochemical data of protein malnutrition in 47% of the cases. Children with abnormal anthropometric measurements and those with a high risk of becoming malnourished (infants with advanced abdominal diseases) were given dietary supplements. In the follow-up evaluation, 90% of the patients showed normal somatic indexes and 76% showed recuperation in their protein values. The recovery of the nutritional status was most important in the group of patients with Acute Lymphoblastic Leukemia.

Adolescent↗
PubMed1992

[Comparison of treatment of acute asthma attacks in children with salbutamol dispensed by the Volumatic dispenser or by a nebulizer].

Eighteen children with acute asthma were administered equal doses of Salbutamol either through a nebulizer and face mask or a dose-metered inhaler, spacer (Volumatic) and tidal breathing mechanism. Consecutive doses at twenty minute intervals were administered until either no significant improvement in pulmonary function was observed or until a cumulative dose of 0.15 mg/Kg (maximum of 5 mgs) had been given. All subjects finally received a dose of 0.15 mg/Kg (maximum of 5 mgs) of nebulized Salbutamol at the end of the study. No difference in bronchodilation was obvious between the methods of treatment. No significant side-effect was observed in any patient. Treatment of acute asthma in children with Salbutamol via a pressurized inhaler, spacer and tidal breathing mechanism may be an efficacious, safe and readily available method, but further work is needed before it can be recommended for routine home management of asthma attacks.

Acute Disease↗
PubMed1991

[Celiac disease. Is its clinical pattern changing?].

Celiac disease (CD) is one of the most malabsorption syndromes in Pediatrics, its diagnosis being based on peroral intestinal biopsy. During the period 1974-1988 we have studied 178 patients with the suspected diagnosis of CD: diagnosis was confirmed in 117 whereas 22 are still under study. Mean age of the patients was 22.5 +/- 22.7 months, diagnosis being made during the first year of life in 32.6% of cases. Most cases had a classic clinical onset, although over the last year symptoms seen to be less apparent. Several patients presented with atypical forms. Also, associated diseases are observed in several cases. CD is often presented nowadays with few or atypical symptoms of difficult diagnosis and in this context the use of immunologic markers may be specially helpful.

Celiac Disease↗
PubMed1991

[Incidence of celiac disease in Vizcaya].

Celiac disease (CD) is a permanent gluten-sensitive enteropathy appearing in individuals genetcally predisposed. Its incidence varies according to the authors, but is situated about 1/1.500 alive newborn infants (ANI). Recently, a decreased in the incidence of the disease as well as a delay in the onset of symptoms have been reported in several countries. The incidence of the disease in Spain is unknown so we have studied it in our population. In the period 1976-1987, 117 patients were suspected to have CD in the different centers performing intestinal biopsies in Vizcaya. Diagnosis was confirmed in 87 cases, thus implying an incidence of 1/2.151 ANI. Age onset has been stable along the years, and most cases continue to be diagnosed during the first 2 years of life.

Biopsy↗