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Biomedical subjects

M Crowley

Publications and source records attributed to M Crowley.

65 records · Page 4Linked to original sources
PubMed1978

Symptomatic bacterial urinary tract infections in men: limitations of quantitative urine cultures.

Occasionally, physicians have discarded the diagnosis of acute symptomatic bacterial urinary tract infection when the urine coutn failed to approach or exceed 100,000 organisms per ml. Previous studies done in women have established the fact that sole reliance cannot be placed on this value to exclude the diagnosis of symptomatic bacterial urinary tract infection. A retrospective analysis of the charts of male patients, with an unequivocal diagnosis of symptomatic bacterial urinary tract infection, demonstrates the limitations of the urine colony count as a diagnostic test in men.

Aged↗
PubMed1976

Lessons learned from a patient. Changing concepts rather than facts.

Many concepts pertaining to urinary tract infections and considered to be established or dogma are, in fact, incorrect or subject to modification. The physician should not be too rigid in his thinking regarding this disorder, as new knowledge constantly becomes available, disproving previously cherished beliefs. The case described appears to underscore this better than any hypothetical situation.

Acute Disease↗
PubMedDate not supplied

Blood pressure and heart rate dynamics during and after exercise in an unselected population.

It has been suggested that the systolic blood pressure (SBP) response to exercise may be useful in predicting future hypertension. However, controversy exists as to whether the SBP response to exercise in borderline hypertensives is actually greater than normotensives or merely increases equally but from a higher resting value. Our aim was to determine the influence of resting SBP, age and sex on changes of SSP during exercise for both healthy subjects and untreated mild hypertensives. Three hundred and eighteen (230 males) underwent a self limited exercise protocol. SBP was measured at baseline and between the 2nd and 3rd minutes of each exercise stage. Age was positively related to SBP at rest and during exercise. The magnitude of SBP change induced by exercise was similar irrespective of the level of resting SBP. The relationship between resting SBP and the absolute SBP change which occurred during exercise was independent of sex. Our findings indicate that (i) age is positively related to SBP at rest and during exercise, (ii) SBP rises equally during exercise irrespective of its resting level and (iii) males and females have a similar pattern of BP response to exercise.

Adult↗
PubMedDate not supplied

Outcome of bone marrow transplantation in acquired and inherited aplastic anaemia in the Republic of Ireland.

BACKGROUND: Severe Aplastic Anaemia (SAA) and Fanconi Anaemia (FA) are rare haematological disorders characterised by pancytopenia and bone marrow hypoplasia. AIMS: We performed a retrospective study of all patients who underwent BMT for SAA and FA at St James's Hospital, Dublin, and at OLHSC, Crumlin, between 1985 and 2002. METHODS: The medical records of 63 patients, 50 with acquired SAA and 13 with FA, were reviewed. RESULTS: The median age at the time of transplant was 14 years (range 3-43 years). The actuarial survival (OS) (n = 63) was 76% at 17 years. The transplant related mortality (TRM) was 22% (n = 14). The most common cause of death was infection (46%). The survival was significantly better in patients receiving their transplant after 1995 (p = 0.002). Outcome was superior in those receiving less than 20 red cell transfusions prior to transplant: OS 91% (< 20 Units) versus 62% (> or = 20 Units). CONCLUSIONS: These national results are comparable to those of published international series and support the use of BMT in the treatment of SAA and FA. The known adverse effect of prior transfusion was confirmed.

Adolescent↗
PubMedDate not supplied

Fever of unknown origin: a view from the community hospital.

A prospective study was performed in a community hospital to determine the specific diseases responsible for "fever of unknown origin." Thirty-four adults with persistent unexplained fever were subjected to extensive diagnostic evaluations. Alcoholic hepatitis and recurrent pulmonary emboli were found to be frequent causes of "fever of unknown origin" in this patient population. Approximately a third of the patients had no disease identified which would have explained the persistent fever. This group of patients, for whom no diagnosis was established, shared an important characteristic: failure to lose more than two pounds/week during the hospitalization.

Adult↗
PubMedDate not supplied

Serum bilirubin levels with antiepileptic drugs.

The incidence of reduced bilirubin levels in 168 outpatients with epilepsy, compared with levels in 69 controls, has been investigated. Highly significant (p less than 0.001) reductions in average bilirubin levels were noted for carbamazepine (CBZ), phenytoin (PHT), phenobarbital (PB), and multiple drug groups. A marginally significant (p less than 0.05) reduction in bilirubin levels occurred in patients treated with valproate (VPA) which, unlike the other drugs, has not been shown to induce hepatic enzymes.

Adult↗
PubMedDate not supplied

Exercise restores seniors' strength and spirits. Fitness plans keep residents of retirement community independent and socially active.

Statistics, an independent study, and anecdotal reports are documenting the health benefits of regular exercise for older adults living at the McAuley Center, a continuing care retirement community in West Hartford, CT. As part of its commitment to holistic health, the center links residents with an on-site fitness counselor, who develops an individualized exercise program and helps motivate residents to stick with it. Residents can choose from individual personal training or rehabilitation programs or group programs such as aerobics or line dancing. The results speak for themselves. For the past five years, only 0.05 percent of the falls at the McAuley Center occurred among the 21 percent of the residents who exercise regularly. In addition, residents and staff alike report increased social interactions among those who exercise. Overall, residents and staff say the benefits of regular exercise contribute significantly to the goal of independent living at the McAuley Center.

Accidental Falls↗