[Assisted ventilation during an asthmatic attack with the aid of sodium oxybutyrate and pancuronium bromide].
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Biomedical subjects
Publications and source records attributed to M Cupa.
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Almitrine is a respiratory analeptic acting on peripherical chemoreceptors. The hemodynamic effects have been studied with chronic respiratory diseases. The works have shown that almitrine produces an increase of pulmonary arterial pressure due to the raising of pulmonary vascular resistances by stimulation of peripherical chemoreceptors. Studying again the hemodynamic investigations with chronical respiratory failure it has been interesting to consider the effects of the produce with patients whose gazometric parameters have been normalized by artificial ventilation at FiO2 = 1, so as to produce a saturation of peripherical chemoreceptors. The results show that infused almitrine keeps hypertensive properties on pulmonary arterial with raising of pulmonary arterial resistances; the pulmonary vasoconstrictor effect is kept in spite of a normalization of blood gases. So it is necessary to look after pulmonary arterial pressure of patients receiving almitrine, that whatever the pre-existing pulmonary arterial pressure may be.
The authors studied changes in erythrocyte lipids in severe infectious syndromes, separating healthy individuals (n = 10) from those with hepatic insufficiency (n = 7). No variations in sphingomyelins were seen. By contrast, the fall in cholesterol and other phospholipids studied (phosphatidylcholine and phosphatidylethanolamine) was highly significant. The difference between the two groups remained clear on the fourth day. No relationship could be established with prognosis and the organism responsible. In conclusion, the authors stress the need for study of the relationships between these changes and erythrocyte functions.
About two cases of "Ogilvie's syndrom" so called colonic ileus or acute idiopathic dilatation of the colon, in patients with chronic bronchitis, the authors discuss the possibility of this etiology like respiratory failure. A rapid colonic decompression is necessary to prevent cecal perforation.
The high risk pregnancies must be admitted in maternity wards with intensive care units for children. As this rule is partially applied, since 1976 the emergency medical service of the Seine-Saint-Denis department accepts to dispatch a mobile care unit for children before birth. So, 182 newborns are taken care of from the very early minutes of life and then leaded in best conditions to a special unit. This work states the place of this type of intervening during the activity of paediatric mobile care unit, the benefits for the newborn, the obstacles and the limits for starting before the birth of such a special unti.
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In cases of major sepsis the erythrocyte lipids undergo significant change especially when there is concomitant hepatic insufficiency and this in turn lead to alteration in the blood viscosity and very probably to the genesis of disorders of coagulation.
Study of changes in erythrocyte lipids after the infusion of 1,000 ml of modified fluid gelatin (Plasmion) demonstrated disturbances at the level of the lipid double layer with, in particular, a decrease in phosphatidyl-ethanolamines found in the serum. No erythrocyte deformation was seen.
The authors have tested a method of teaching the arrhythmias with a simulating machine. Two groups of students have been drawn by lot and have set for a first test on their knowledge about dysrythmias. One group was instructed in a classical way, the second one was instructed with the simulating machine which reproduces the majority of rhythm modifications on electrocardioscopic screen. At the end of the teaching, a post-test took place, then a last one a month later. The comparison of the two methods by measuring the residual knowledge enables to prove the interest of using simulating machine to teach disorders of cardiac rhythm.
Two methods used to measure the degree of the forces involved, in an experimental model--a polyethylene film stretched over a drum, during the penetration of different short venous catheters were compared. One involved strain gauge force sensors, whilst the other used simple and easy to use equipment. The forces necessary for the penetration of introducer needles are on the one hand relatively slight and secondly quite close to each other. By contrast, there are wide differences between the degree of force necessary to obtain penetration of the catheter itself. These forces are in general less for teflon catheters than for those made of polypropylene. The degree does not appear to be related to the size. It remains to attempt to establish a correlation between ease of penetration and tolerance.
In the light of experimental studies on balloons of several intubation tubes, the concepts of occlusive pressure, tracheal pressure and minimum occlusive volume are defined and dissociated. An in vivo study made it possible to determine the importance of the tracheal mucous pulse, the suppression of which could contribute to tracheal stenosis.
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About one case of necrotising enterocolitis following an extra-peritoneal and aseptic operation, it seems that a post-operative ileus, by the ischemia of mucous membrane and the swarming of anerobics that it involves, seems to be responsable of this dreadful complication. The macroscopic and deceiver aspect of intestine to an early re-operation can impeed this diagnosis. The hyperbaric oxygenotherapy seems to be a perceptible adjuvant treatment.
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