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Biomedical subjects

M Czochra

Publications and source records attributed to M Czochra.

At least 19 recordsLinked to original sources
PubMed1997

[Biological and clinical significance of acute phase proteins with particular emphasis on the role of C-reactive protein].

The acute phase response is a non-specific, early phenomenon, in which the concentration of a number of plasma proteins is increased following most forms of tissue injury, bacterial infection, inflammation, malignant neoplasia and surgical procedures. These plasma proteins are collectively termed acute-phase proteins. Their most important role is to restore the homeostasis of human organism. C-reactive protein (CRP) regarding his dynamic reaction, is one of the best non-specific biochemical indicators of most disorders. The multiple quantitative measurement of CRP is usefull in the diagnosis, differentiation, the assessment of treatment effectiveness and patient's prognosis, additionally to other clinical parameters.

Acute-Phase Proteins↗
PubMed1997

[Theories of intracranial aneurysm etiology].

The main theories of the origin of intracranial aneurysms as the most common vascular malformations are presented. Three main theories maintain that they are either the congenital, acquire or both of those defects. The presence of aneurysms in the bifurcations of the arteries with the loss of the muscle layer and the coexistence with other vascular malformations of the arteries and their rareness in children give the evidence of the acquire origin. The present theories join this two positions and take into consideration also the hemodynamic and inflammation as well as degeneration, atheromatosis, toxic and traumatic factors.

Hemodynamics↗
PubMed1992

[Brachytherapy of brain gliomas].

Radiotherapy is considered presently the most advantageous supplementary method after surgical treatment for gliomas. The limitations of classical teletherapy cause that interstitial radiation may become preferable. The authors present the theoretical principles and practical application of brachytherapy in 10 cases of glioma. Closed radioactive sources were used in form of I125 implanted stereotactically into brain tumours for a period sufficient for providing therapeutic radiation dose to the border of the tumour. The doses received by tumour borders ranged from 812 to 4560 cGy, and the mean dose was 2064 cGy. Five patients were given additionally 6000 cGy by teleradiotherapy.

Adolescent↗
PubMed1980

[Angiographic evaluation of the effectiveness of surgical treatment of intracranial aneurysm].

On the basis of control angiographies after surgical treatment of 59 intracranial aneurysms full effectiveness of aneurysm elimination from the circulation was assessed and found to be fully effective in 93.2% of cases. In 3 cases the aneurysmal sac was partially visualized, and in 2 cases the metal clip was found to have slipped off from the aneurysm neck. One of these patients was reoperated successfully. The investigations demonstrated in 17 cases (29%) presence of postoperative vasospasm, in 8 cases internal hydrocephalus following past bleeding and in 2 cases accumulation of cerebrospinal fluid in the subdural space. On the basis of literature reports and own experiences the authors stress the necessity of possibly early control angiography which should be accepted as a routine method. In case of internal hydrocephalus demonstration insertion of a ventriculoatrial shunt is suggested.

Adolescent↗
PubMed1980

[Results of surgical treatment of aneurysms of the anterior communicating artery].

The authors present the results of surgical treatment of 48 aneurysms situated on the anterior communicating artery operated upon by the classic and microsurgical methods. The latter method has made it possible to raise the proportion of very good and good results from 23% in the classic method to 70%, and to reduce the postoperative mortality in groups I and II of condition severity from 13.6% to 4%. Independently of the method used Korsakoff's syndrome was observed in 17% of cases. The high value of Yasargil's surgical approach is stressed.

Adolescent↗
PubMed1980

[Cerebral aneurysm associated with meningioma in the area of small wing of the sphenoid bone].

A patient is described in whom removal of meningioma situated on the small wing of the sphenoid bone was followed by haemorrhage from an aneurysm of the middle cerebral artery. The aneurysm was recognized only after angiography was done after the operation for brain tumour. The problem of lack of visualization of aneurysms situated in the vicinity of brain tumours and diagnostic difficulties in cases of coexistence of these diseases are discussed.

Adult↗
PubMed1980

[Chronic bilateral subdural hematoma].

The authors report 31 patients treated surgically for chronic bilateral subdural haematomas stressing the diagnostic difficulties in such cases and discussing the value of radiological investigations and surgical methods, especially multipoint trepanation.

Adult↗
PubMed1979

[Case of cerebral aneurysm, arteriovenous fistula and cerebral hematoma].

A female patient is reported who had subarachnoid haemorrhage and in whom angiography demonstrated presence of an aneurysm and an arteriovenous angioma in the territory of the left middle cerebral artery. During surgical intervention an intracerebral haematoma was found additionally in the posterior part of the left temporal lobe. The postoperative course was uneventful. The patient was discharged without evidence of focal brain injury.

Adult↗
PubMed1979

[Giant intracranial aneurysm].

The authors describe a case of a giant intracranial aneurysm of the left internal carotid artery in which signs of raised intracranial pressure predominated. In view of presence of internal hydrocephalus Holter's valve was implanted. The aneurysm was excluded from the circulation by trapping the afferent vessel. A good therapeutic result was achieved.

Adult↗
PubMed1975

Prevention of experimental gastric ulcers in rats by dial derivatives.

In 111 rats divided into 5 groups, Ipronal (5-allyl-5-(beta-hydroxypropyl)-barbituric acid) protected rats from development of experimental ulceration of the gastric mucosa twice as effectively as diallylbarbituric acid and compound D2H (5-isopropyl-5-(beta-hydroxypropyl)-barbituric acid). Compound D1S (alpha-allophanyl-alpha-allyl-gamma-valerolactone) was devoid of this action.

Animals↗