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Biomedical subjects

M D Berkman

Publications and source records attributed to M D Berkman.

17 recordsLinked to original sources
PubMed1992

Microvascular groin flaps in the treatment of hemifacial microsomia.

The use of free microvascular groin flaps, both myocutaneous and osteocutaneous, is described in five patients with hemifacial microsomia. Flaps were designed according to the degree of soft tissue and skeletal abnormality. Long-term results are described. Though the majority of patients with hemifacial microsomia do not require free flap grafts, the procedure does present as a viable approach to severe tissue deficiency with excellent results.

Adolescent↗
PubMed1980

Velopharyngeal insufficiency in the facio-auriculo-vertebral malformation complex.

Twenty-two patients with the Facio-Auriculo-Vertebral Malformation Complex (hemifacial microsomia) were examined with multi-view videofluoroscopy and nasopharyngoscopy at rest and during speech. Fifty-five per cent of the subjects had velopharyngeal insufficiency (VPI) and hypernasal speech. Only two of these 12 subjects had cleft palate. VPI was related to structural and physiological asymmetry of the pharynx. No relationship was found between the severity of facial malformation and the presence of VPI.

Adolescent↗
PubMed1979

Pharyngeal hypoplasia in Treacher Collins syndrome.

Examination of 11 patients with Treacher Collins syndrome (TCS), with the use of multiple-view videofluoroscopy and nasopharyngoscopy of the pharynx, disclosed marked narrowing of the airway. In several patients, the pharynx was less than 1 cm in width at its most narrow point. It is thought that reduced airway in TCS may help to explain the frequent reports of neonatal death associated with the syndrome. Pharyngeal narrowing was found throghout the entire vertical height of the pharynx in all 11 patients. Pharyngeal hypoplasia is probably responsible for reported difficulties in intubating patients with TCS for endotracheal anesthesia and for respiratory complications after palatoplasty and pharyngoplasty. Pharyngeal hypoplasia is considered to be a primary feature of the syndrome and may aid in its diagnosis.

Adolescent↗
PubMed1978

Early non-surgical closure of postoperative palatal fistulae.

Ten of 11 patients who developed oronasal fistulae subsequent to palatoplasty and/or pharyngeal flap operation obtained complete physiological closure of the fistula by using a vinyl palatal appliance for a two to three month period. All these fistulae were diagnosed within 10 days to two weeks after the surgery, and the appliance therapy was started immediately. We believe this treatment to be an effective, uncomplicated method for non-surgical closure of recent postoperative oronasal fistulae.

Adult↗
PubMed1978

Clinical application of the functional matrix: mandibular reconstruction and monobloc functional therapy.

A 13-year-old black girl with an extensive ameloblastoma of the mandible required subtotal mandibular resection and immediate reconstruction with use of an autogenous, ipsilateral, corticocancellous graft from the iliac crest and monobic functional therapy. Twenty-seven months later, clinical evaluation showed normal mandibular function and no facial asymmetry. Bony architectural changes after 27 months included reformation of the coronoid process, angular process, and external oblique ridge; preservation of mandibular length and thickness; and maintenance of the alveolar ridge height. The reformation of the coronoid process suggests the importance of the functional matrix (temporalis muscle) in skeletal tissue growth. The monobloc appliance in conjunction with bone grafting is an effective means for transmission of biophysical stimuli and for maintenance of appropriate stress for remodeling of bone in the mandible.

Activator Appliances↗
PubMed1978

A new syndrome involving cleft palate, cardiac anomalies, typical facies, and learning disabilities: velo-cardio-facial syndrome.

This report describes a pattern of similarities among 12 patients which are felt to represent a newly recognized congenital malformation syndrome. The symptoms shown most consistently by the 12 patients were overt or submuscous clefts of the secondary palate, ventricular septal defects, typical facies, and learning disabilities. Other symptoms were noted with varying frequency. The occurrence of velopharyngeal insufficiency in all twelve patients reflected poor motion in the lateral pharyngeal walls, thus necessitating specific forms of treatment. Treatment was often dependent on the extent of cardiac lesions.

Abnormalities, Multiple↗
PubMed1971

Demonstration of the lyon hypothesis in X-linked dominant hypoplastic amelogenesis imperfecta.

The present study is in agreement with the Lyon hypothesis as indicated by the random pattern of vertical bands of normal-appearing and hypoplastic enamel in the proposita and the mother. Further studies which would quantitate the amount of normal-appearing and hypoplastic enamel in a lage number of teeth with the X-linked hypoplastic type of amelogenesis imperfecta may provide further data in support of the Lyon hypothesis as it applies to this condition. Even though the methodology employed in this study involves nothing more sophisticated than pedigree analysis and clinical appraisal, it purports to demonstrate and support the validity of the Lyon hypothesis concerning amelogenesis imperfecta in man.

Adult↗