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Biomedical subjects

M D Calvo

Publications and source records attributed to M D Calvo.

4 recordsLinked to original sources

Prostaglandin F2a (PGF2a): an inadequate marker of the vitality of wounds?

We have studied the viability of PGF2a as a vitality marker in skin wounds. Incised vital skin wounds and homolateral control pieces of skin were obtained from 20 autopsies performed at the Institute of Legal Medicine of Coimbra University (Portugal). We have also studied 10 fresh skin samples from the Department of Dermatology of the University Hospital (Granada). Our results show that PGF2a is not suitable for the diagnosis of the vitality of wounds because of its irregular behaviour.

Biomarkers↗

[Acetate metabolism: experimental study].

Plasma levels of ethanol and acetate, which is the end product of hepatic ethanol oxidation, have been studied in 60 rats. Animals were divided into two groups: 1) Control rats, and 2) Alcohol-treated rats. Ethanol and acetate were measured without any previous handling (endogenous levels) and after intraperitoneal injection of a single dose of ethanol. Blood specimens were taken at 30, 60, 120, 180 and 240 minutes after ethanol injection. Plasma levels of ethanol and acetate were performed by Head Space Gas Chromatography. Alcohol-treated animals had higher plasma acetate levels than control ones. There were statistically significant differences for acetate between both groups of rats at 0, 30, 120 and 180 minutes.

Acetates↗

[Autistic syndrome associated with refractory temporal epilepsy].

Autism is a psychopathological disorder of childhood characterized by severe lapses in behaviour and cognition and excessive presence of extravagant unsuitable behaviour that affects a child's development. It is associated with different conditions of the Central Nervous System, especially a high incidence of epilepsy. We report a case of autistic syndrome with refractory temporal epilepsy, describing its clinical onset, (type of seizures, focal anomalies on the EEG, evidence of relation between limbic disfunction and autism.

Autistic Disorder↗