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Biomedical subjects

M D Cooke

Publications and source records attributed to M D Cooke.

6 recordsLinked to original sources
PubMed2002

Submicrometer ferromagnetic NOT gate and shift register.

An all-metallic submicrometer device is demonstrated experimentally at room temperature that performs logical NOT operations on magnetic logic signals. When this two-terminal ferromagnetic structure is incorporated into a magnetic feedback loop, the junction performs a frequency division operation on an applied oscillating magnetic field. Up to 11 of these junctions are then directly linked together to create a magnetic shift register.

Journal Article↗
PubMed1984

Synthesis and radiochemical stability of 14C-cefotaxime.

14C-Cefotaxime (14C-HR 756) has been synthesised with the radiolabel in the sidechain aminothiazole ring by a multistep sequence starting from 14C-thiourea. A high specific activity batch (10400 microCi g-1), and a low specific activity batch (57.1 microCi g-1) suitable for intravenous human use were prepared; their purity, and solid-state and aqueous solution stability, are described.

Carbon Radioisotopes↗
PubMed1976

Pulmonary resistance and methods of humidification in acute pulmonary failure.

In order to evaluate the effects of ultrasonic nebulization on airway resistance in respiratory failure, ten patients requiring mechanical ventilation for acute pulmonary failure were each ventilated with two humidification systems, one producing inspired air saturated with vapour at 35 degrees C, the other nebulizing water droplets ultrasonically. There was no statistically significant difference in pulmonary resistance at inspiratory flow rates of 40, 60, AND 80 1/min. A separate comparison between humidifiers in those patients with the highest resistances did not reveal any difference in response to method of humidification. In contrast to studies in other contexts, these data fail to show any significant difference, from the standpoint of effects on resistance, in the use of ultrasonic mist humidification during mechanical ventilation for respiratory failure.

Acute Disease↗
PubMed1976

Antibiotic resistance among coliform and fecal coliform bacteria isolated from sewage, seawater, and marine shellfish.

Seawater and shellfish samples collected in the vicinity of a marine sewage outfall were examined for the incidence of antibiotic resistance among coliform and fecal coliform bacteria over a 2-year period. Seventy percent or more of these two groups of bacteria from both sources were resistant to one or more antibiotics. Forty-five percent of the isolates resistant to streptomycin or tetracycline were capable of transferring all or part of their resistance pattern to an antibiotic-susceptible strain of Escherichia coli K-12.

Anti-Bacterial Agents↗
PubMed1976

Antibiotic resistance among coliform and fecal coliform bacteria isolated from the freshwater mussel Hydridella menziesii.

Freshwater mussels (Hydridella menziesii) collected from Lakes Rotoroa, Rotoiti, and Brunner, South Island, New Zealand, contained coliform and fecal coliform bacteria. The majority of these bacteria were resistant to one or more antibiotics, but none transferred streptomycin, tetracycline, or kanamycin resistance to an antibiotic-susceptible strain of Escherichia coli K-12.

Animals↗