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Biomedical subjects

M D Ibragim

Publications and source records attributed to M D Ibragim.

4 recordsLinked to original sources
PubMedDate not supplied

[Reflexometry: an early prognostic test for assessing postoperative hypothyroidism].

The serum content of thyroxin (T4) and the duration of Achilles reflex was studied in 23 patients with toxic goiter 1-3 months after subtotal thyroidectomy. Concentration of T4 assessed in the serum revealed 9 euthyroid subjects and 14 patients with hypothyrosis. But as the duration of Achilles tendon reflex was within the norm in all 14 hypothyrosis patients reflexometry technique turned to be inconsistent in distinguishing between hypo- and euthyroidism. However the high prognostic value of this method for differential diagnosis of transient or long-standing forms of the disease was shown. Six months after the surgery hypothyrosis disappeared spontaneously, i.e. turned to be transient, in 5 patients whose Achilles tendon reflex parameters were normal, though in all 9 hypothyrosis patients with the reflex parameters higher than 350 m/s clinical and biochemical signs of thyroid under-activity were detected. The data obtained give evidence in favour of reflexometry to be used for early prognostic assessment of post-operative hypothyrosis.

Achilles Tendon↗
PubMedDate not supplied

[Lymphoid infiltration of the thyroid gland and antithyroid antibodies in patients with diffuse toxic goiter].

The titer of antibodies to thyroglobulin (TgAb) was determined in 59 patients with diffuse toxic goiter before and in 21 patients 1.3 and 6 mos. after subtotal resection of the thyroid using the hemagglutination test (HAT), radioimmunoassay (RIA) and indirect immunofluorescence (IF). Microsomal antibodies were determined by the latter method only. Using the HAT TgAb were detected in 85% of the patients, using RIA and IF in 40 and 44%, respectively. A high titer of thyroid antibodies was detected on an average in 11-15% of the patients. Positive correlation was found in comparing the titer of thyroid antibodies with a degree of the expression of the thyroid lymphoid infiltration (TLI). It was most significant when it was between the titer of microsomal antibodies and TLI expression. The presence and severity of endocrine ophthalmopathy did not correlate with the TgAb titer. A tendency to the disappearance of TgAb or the reduction of their titer was noted in the first 6 mos. following operation.

Adolescent↗