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Biomedical subjects

M D Kniazev

Publications and source records attributed to M D Kniazev.

At least 91 records · Page 5Linked to original sources
PubMed1975

Arterial-wall tissue factors influencing haemocoagulation, and their release into circulation in endarterectomy.

The wall of lover-limb arteries affected with severe atherosclerosis contains a Complex of substances with pro- and anticoagulative activities. The arterial wall, traumatized in endarterectomy by separation of the individual coats, releases procoagulative substances into blood circulation. The most conspicuous local manifestations of hypercoagulation and hypofibrinolysis appear on the day of surgery. The artery operated upon releases the thromboplastic factor for nine days; substances shortening the thrombin time (antiheparin substance, thrombin accelerator), for five days; and inhibitors of fibrinolysis, for four days after operation. A correlation was found between the regenerative process in the endarterectomized artery and the dynamics of the release of tissue factors influencing the haemocoagulation.

Animals↗
PubMed1975

[Coronary reserve and differentiated therapy of its disorder].

The clinical course of the ischaemic heart disease was studied and compared with the ECG indices at rest, and under exercises, and with the data of selective coronary angiography in 189 patients. Three stages of decompensation of the coronary reserve were revealed. The efficiency of drug therapy and the indications for surgical management were studied with reference to the state of the coronary reserve.

Adrenergic beta-Agonists↗
PubMed1975

[Experience with the use of izoptina].

The effect of isoptin was studied in 271 patients with ischemic heart disease and various disturbances of the cardiac rhythm. Clinical, functional indices and coronarographic findings proved the drug to be highly effective. The mechanism of its action is discussed.

Angina Pectoris↗
PubMed1975

[Surgery of occlusive lesions of the brachiocephalic trunk].

A detailed analysis of 33 cases of operations on the brachiocephalic trunk is reported. An experience with surgical treatment for occlusive lesions of the brachiocephalic trunk of various etiology to liquidate chronic ischemia of the brain has evidenced that in aorto-arteritis the prosthesizing of the brachiocephalic trunk with synthetic prosthesis yields the most favourable results.

Adolescent↗