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Biomedical subjects

M D McGee

Publications and source records attributed to M D McGee.

9 recordsLinked to original sources
PubMed1997

Temporal lobe perfusion asymmetries in schizophrenia.

UNLABELLED: Structural and functional neuroimaging techniques have consistently demonstrated that abnormal lateralization of temporal lobes may be important in identifying the pathophysiologic processes in schizophrenia. The exact nature of these reported abnormalities has not been consistent. METHODS: We examined temporal lobe perfusion using HMPAO-SPECT in 22 individuals with schizophrenia in an effort to establish whether temporal lobe perfusion asymmetry is seen in these individuals, as compared to a group of 22 age- and sex-matched controls. RESULTS: We found that the asymmetry index, a measure of perfusion differences between two homologous compared areas, was lower (more negative) in schizophrenic individuals. The asymmetry indices of patients considered with the results from globally corrected ROI means indicated that the left temporal lobes of individuals with schizophrenia were significantly hypoperfused when compared to controls. This finding does not appear to be caused by medication effects, demographic variables, handedness, imaging artifacts or analysis techniques. CONCLUSION: In our sample, patients with schizophrenia appear to have significant left hypoperfusion relative to right of their temporal lobes. Abnormal lateralization of temporal lobe blood flow may have important clinical implications by assisting with diagnosis and appropriate treatment for individuals with schizophrenia.

Adolescent↗
PubMedDate not supplied

Rethinking patient placement: the human service matrix model for matching services to needs.

The improvements in both clinical and fiscal outcomes necessary for prosperity in the current healthcare environment require a rethinking of our conceptual approaches to patient assessment, treatment planning, and service delivery. Conventional practice rests in part on the Level of Care concept, which assigns intensities of both clinical services and treatment settings in a linked manner according to impairment severity. Although this approach has resulted in more efficient matching of resources to needs, it is overly restrictive, and does not speak directly to the need to match both healthcare and social services (including treatment setting) to human needs for treatment to be successful. The Human Service Matrix model presented in this article delinks clinical from social services and creates a conceptual framework for integrating social and healthcare services in the cure of patients with addictions. Our experience with this model suggests it has heuristic value in promoting cost and outcome effective treatment.

Adult↗
PubMedDate not supplied

Databases for psychiatrists.

Advances in computer technology have made databases more widespread and accessible, bringing both opportunities and benefits to psychiatrists. Their increasing usefulness has also resulted in increased expectations by others, such as accrediting agencies and payers, that psychiatrists have the capacity to manage outcome and utilization data as well as other information. This paper provides an overview of the uses of databases in psychiatry, describes basic principles and features of relational databases, and reviews some of the features of currently available database-development packages.

Databases as Topic↗