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Biomedical subjects

M D Shah

Publications and source records attributed to M D Shah.

At least 19 recordsLinked to original sources

Study of EEG and CT scan in neurologically normal cases of focal convulsions.

Twenty-three neurologically normal children with focal convulsions were studied with EEG and CT scan. Thirty-five per cent had an abnormal CT scan. Lesions of potential therapeutic significance were seen in 30 per cent of all scans. Abnormalities detected on CT scans were as follows: tuberculomas, five cases; acute infarct, one case; gliosis, one case; multiple cortical cysts, one case. All the cases with intracranial tuberculomas were aged more than 5 years. A good correlation was found between the EEG and the CT scan findings. Maximum percentage (57 per cent) of CT scan abnormality was seen in cases exhibiting focal abnormality on EEG and minimum percentage in those with a normal EEG (18 per cent).

Brain

Enzyme-linked immuno-assay for the detection of mycobacterium tuberculosis specific IgG antibody in the cerebrospinal fluid in cases of tuberculous meningitis.

The efficacy of enzyme-linked immuno-assay in the detection of IgG antibody against mycobacterium tuberculosis in the cerebrospinal fluid of patients suffering from tuberculous meningitis was measured in 50 children consecutively admitted to hospital. The controls were 15 cases of tuberculosis other than of the central nervous system; 24 cases of pyogenic meningitis; 19 cases of neurologic problems but with essentially normal cerebrospinal fluid. The specificity of the test ranged from 93 to 100 per cent and the sensitivity from 82 to 95 per cent.

Antibodies, Bacterial

Late hemorrhagic disease of infancy.

Over a period of 1 1/2 years, 9 infants ages ranging between 3 weeks and 7 months presented with the syndrome of late hemorrhagic disease related to vitamin K deficiency. All were exclusively breast fed and had not received vitamin K at birth. Four of these had acute intracranial hemorrhage, of which 2 expired and the surviving 2 have residual neurologic handicap. Of the remaining 5 who had skin and mucosal bleeds, all recovered on administration of vitamin K.

Blood Coagulation Tests