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Biomedical subjects

M D'Amore

Publications and source records attributed to M D'Amore.

At least 37 records · Page 2Linked to original sources
PubMed1989

[Linear bone densitometry by monochromatic photon absorptiometry. A study of a normal population in Apulia].

An epidemiological survey was conducted on a group of Apulian residents in order to compare the densitometric data obtained with those produced by other European and North American authors. The results confirm the need for personal data on our own population given the often significant differences in order to avoid errors in monitoring patients who may require even long-term treatment.

Absorptiometry, Photon↗
PubMed1989

[Physician-patient relations in rheumatology].

In a further attempt to tackle the question of the doctor-patient relationship in rheumatology, this time more comprehensively and from a different angle, the mistakes a doctor may make in daily practice are indicated. In effect, since the doctor's himself a kind of "drug", only his "correct administration" will effectively solve certain of the patient's psychological problems.

Adult↗
PubMed1987

Evaluation of mineral metabolism and bone turnover in osteoporotic females treated with phosphorus and salmon calcitonin.

Twenty-five patients with radiological and clinical evidence of osteoporosis were studied. Nineteen patients received oral phosphorus at a dose of 1,000 mg/die for 10 days followed by salmon calcitonin (100 U MRC/die) for 20 days. Six patients received only oral calcium at a dose of 1,000 mg/die). In the first group, a significant increase in serum osteocalcin and parathyroid hormone, after administration of phosphorus and persisting after treatment with salmon calcitonin, was found. No variation in the controls was observed. In a later study, a significant increase in serum 1,25 dihydroxyvitamin D (1,25(OH)2D3), after receiving phosphorus and persisting after salmon calcitonin, was demonstrated. In accordance with the authors' results, phosphorus could be considered a useful activator of bone formation and this stimulus by parathyroid hormone was mediated. Finally, the positive effects of phosphorus on circulating 1,25(OH)2D3 must be considered for a good treatment protocol of osteoporosis.

Administration, Oral↗
PubMed1987

[Changes in urinary serotonin in subjects treated with calcitonin].

In a first stage, the authors have evaluated the relationship between plasma calcitonin and urinary serotonin in patients presenting a chronic pathology, mostly of respiratory nature. The results have demonstrated that plasma calcitonin and urinary elimination of serotonin were increased (p less than 0.05) in patients presenting a chronic pathology, compared to 16 healthy patients of the same age and sex. In a second stage, the authors have evaluated the variations of urinary serotonin 24 hours after injection of 100 U MRC of calcitonin from salmon, in the same patients. The results showed (p less than 0.001) an increase of urinary serotonin at 24 hours. This increase is not observed after injection of eel or human calcitonin. The effect of the various calcitonin on serotonin metabolism is discussed.

Aged↗
PubMed1986

[Psychalgia in rheumatology. Methods of approach and intervention].

The observation of several cases triggers a review of psychological pain in rheumatology. Such situations require a thorough grounding on the part of the rheumatologist who must work with the psychiatrist and clinical psychologist in the treatment of such patients. The importance of teamwork and the need for clinical psychologists and psychiatrists in rheumatology wards is emphasised and the approach and treatment techniques to be adopted for patients suffering from so-called psychological pain are outlined. Essentially, the first (approach) stage involving several phases will be followed by a second stage to be evaluated by the team in an attempt to provide the patient with the most appropriate treatment.

Adolescent↗
PubMed1985

25-Hydroxycholecalciferol in experimental osteoporosis.

UNLABELLED: The authors, using the experimental pattern of bone rarefaction induced by a low calcium diet, tried to determine if 25-hydroxycholecalciferol, administered at doses and according to procedures similar to those used in osteoporosis, might interfere in such a process of rarefaction. The statistical evaluation of the results concerning the size of the amount of spongy bone presented evidence for the sharp decrease in the specific bone volume in rats placed on a low calcium diet as compared to control rats. Such a difference is found even between rats treated with 25-OH-D3. Nonetheless, the authors reported a difference--although not statistically significant--that indicated an increase in the amount of bone in rats on a normal diet but treated with vitamin D as compared to control rats. IN CONCLUSION: 25-OH-D3 by itself, the diet being the same, was not able to ameliorate the amount of bone.

Animals↗
PubMed1985

[Evaluation of the effects of anabolic steroids, calcitonin and 25-hydroxycholecalciferol on the spongy bone of rats].

Prevention of the experimental bone rarefaction which occurs in rats put on a low calcium diet was attempted by using salmon calcitonin and 25 hydroxyvitamin D given with a similar regimen to that used in human disease. Results were compared with the previously reported effects of synthetic anabolic steroids. Statistical analysis was carried out on measurements of cancellous bone mass. No statistically significant increase in the femoral trabecular bone volume occurred in rats put on an hypocalcemic diet plus treatment by calcitonin and vitamin D whereas such an increase had been noted when anabolic steroids were used. Measurement of the trabecular bone volume of proximal and distal epiphyses demonstrated a statistically significant difference between rats on a hypocalcemic diet treated by 25-OH-D3 and rats treated by calcitonin or controls on a normal diet. In rats on a normal diet, 25 hydroxyvitamin D led to an increase in bone mass which did not reach statistical significance but is probably explained by improvement in calcium intestinal absorption.

Anabolic Agents↗
PubMed1984

[Polymyalgia rheumatica: a systemic vasculitis. Review of the literature and presentation of 2 clinical cases].

A brief historical account of the nosological and pathogenetic classification of rheumatic polymyalgia (RPM) is followed by an indication of the importance of vasculitis during its course. Elective involvement of the temporal artery is not always observed, though there may also, or exclusively, be involvement of other arterial districts, such as those of the subaxillary and subclavicular, that of the thoracic and abdominal aorta, and of the large branches of the lower limbs. Two clinical cases are presented in support of these assertions. It is also shown that arteritis may appear several months after the onset of RPM, and that its progress may be quite separate from that of the latter. Doppler examination is now of assistance in the diagnosis of these forms, since it permits exploration of the various districts and the detection of subclinical lesions. It is also useful in the monitoring of arteritis and its response to treatment.

Aged↗
PubMed1984

[Variations in the ratio of total calcium to plasma calcium ions in chronic liver diseases].

Total Ca and Ca++ were evaluated with a Perkin Elmer 305 atomic absorption spectrophotometer and a specific Orion 93-20 electrode respectively in 29 cirrhotics and 76 non-cirrhotics. Stress is laid on the reliability of the Orion electrode. Mean C++ was 52.02 +/- 4.46 mg% in the non-cirrhotics, in cirrhotics was 49.90 mg% +/- 6.14 mg%. An inverted ratio vis-à-vis total Ca was also noted: 54.73 +/- 3.65% in the cirrhotics and 56.51 +/- 3.73% in the non-cirrhotics. Although lacking in significance, these data underscore the importance of both partial and total evaluation of plasma Ca in the prevention of mistaken therapeutic approaches when liver patients.

Adult↗
PubMed1983

[Immuno-histological findings on Sjögren's syndrome].

Six cases of SS, 12 cases of SS in association with other diseases (AR, LES, MCTD, SSP) and 14 cases of various diseases with no clinical signs of SS (AR, UCTD, LES, MCTD, PM, cutaneous PAN, Scheuermann's disease, ankylosing spondylitis) have been examined. Examination of the patients included general clinical, stomatological and ophthalmological examinations, slit lamp and Schirmer I test, labial biopsy direct immunofluorescence on labial biopsy, indirect immunofluorescence on labial biopsy of a healthy subject scialography and salivary scintiscan. Various seroimmunological tests were also performed--in the hope of identifying LE, ANA, anti-ENA and anti-dsDNA factors. The results of these clinical, immunological, bioptic and instrumental tests were studied with a view to clarifying the diagnostic and nosographic problems of the syndrome. The diagnostic importance of immunological and instrumental tests is emphasized. Labial biopsy in particular also makes it possible to quantify the glandular lesion to some extent as well as providing other histological data regarding any associated disease. Nosographically, it is suggested that SS be definitively included among the connective tissue diseases in recognition of its polymorphism and variety of clinical forms which cover a wide range from definite SS, whether in pure form or associated with other diseases, to "subclinical" SS in systemic diseases.

Antibodies, Antinuclear↗
PubMed1983

[Evaluation of the percentage of increased spongy bone in experimental osteoporosis treated with synthetic anabolic agents].

In this paper, the authors discuss the variations in the quantity of spongy bone in rats of the same sex, same age and same weight subjected to a normocalcic diet, a hypocalcic diet or a hypocalcic diet plus synthetic anabolic agent. In the rats subjected to a hypocalcic diet, there is a statistically significant reduction in the quantity of spongy bone, in comparison to that of the other two groups. In other words, the hypocalcic diet led to a rarefying osteopathy, which was partially prevented by the use of synthetic anabolic agents. the authors also observed that the rarefying osteopathy was more intense in the distal epiphysis of the femur than in the neck of the femur. If this feature is confirmed in man, it would constitute a precious aid to the early detection of osteoporosis.

Anabolic Agents↗
PubMed1981

[Various forms of secondary lumbosciatic pain in children and adults].

Reference is made to two personal cases in underscoring the fact that meralgia paraesthetica, though regarded as a form that displays a preference for adult males, must be considered as extended to subjects of all ages when a benign or malignant neoformation irritating the L2 root or its trunk is involved. Before classifying a case as idiopathic, therefore, one must rule out the possibility of intra-abdominal disease-usually malformative in young subjects, and benign or malignant in persons of all ages. Lastly, stress is laid on the fact that atypical lumbar and sciatic pain in the adult may be secondary to aneurysm of the abdominal aorta, the common iliacs and the hypogastric. Hence the need to look for such conditions symptomatologically.

Aorta, Abdominal↗
PubMed1981

[The value of the calcitonin test in Paget's disease of bone].

Five untreated patients with Paget's disease and one who had been unsuccessfully treated with porcine calcitonin for 2 years were given 20 mg/kg/day disodic ethydronate. Alkaline phosphatase and urinary hydroxyproline values were examined and the progress of the calcitonin test was followed. In addition to being of great importance and in line with the other two parameters in following the course of the disease, this test was found to be an excellent pointer to the moment when no further response is being obtained from treatment with calcitonin.

Aged↗
PubMed1981

[Duodenal absorption of calcium in rats treated with 25 OHD3, diphosphonates and synthetic anabolics].

In this study the authors developed new technics of study of duodenal absorption of calcium in rats: atomic absorption spectrophotometry, and dialysis to equilibrium. We considered that the main factors necessary for evaluation of duodenal absorption of calcium are the serum calcium, the calcium and alkaline phosphatase present in the duodenal cells and the calcium-binding proteins. The authors demonstrate that these factors are highest in rats treated with 25 OHD3 and norandrostenolone decanoate, than in control rats. In rats treated with diphosphonate, on the contrary, they obtained a reduction in the values of calcium and alkaline phosphatase contained in the duodenal cells.

Anabolic Agents↗