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Biomedical subjects

M Daras

Publications and source records attributed to M Daras.

52 records · Page 3Linked to original sources
PubMed1985

Alopecia in meralgia paresthetica.

Meralgia paresthetica has been described as a common affliction of the lateral femoral cutaneous nerve, creating the symptoms of numbness, tingling, and paresthesias in the overlying areas of the lateral and anterior thigh. It is second only to sciatica in peripheral nerve diseases of the lower extremity. We present two patients with classic symptoms of meralgia paresthetica and nonscarring alopecia overlying and demarcating the areas of paresthesias. Meralgia paresthetica should be included in the differential diagnosis of localized alopecia of the anterior or lateral thigh.

Aged↗
PubMed1985

Central nervous system involvement in patients with acquired immune deficiency syndrome (AIDS).

Central nervous system involvement occurred in 28 of 121 patients with acquired immune deficiency syndrome (AIDS). The major risk factor in this AIDS population was intravenous drug abuse (64%). A neurologic symptom or disability was the principal reason for hospitalization in 16 cases (57%). Three patients had primary lymphoma of the brain and the remainder had opportunistic infections. Patients with focal neurological features usually had toxoplasmosis. Progressive headache and meningeal signs occurred with cryptococcosis. A progressive subacute dementia was probably due to cytomegalovirus. Other infections included atypical mycobacteria, candida, herpes zoster and possible progressive multifocal leukoencephalopathy.

Acquired Immunodeficiency Syndrome↗
PubMed1983

Familial spinocerebellar ataxia with skin hyperpigmentation.

Previous reports have shown the association between familial spastic paraplegia and hypopigmentation of the skin. A family is reported in which three siblings presented with progressive spastic paraparesis and cerebellar ataxia. All the siblings had large hyperpigmented naevi of the lower extremities while none of the unaffected members had a skin lesion. A definite association appears to exist between heredo-familial ataxias and disordered skin pigmentation, but the exact mechanism remains unclear.

Adult↗
PubMed1981

'Stiff-man syndrome' in an adolescent.

A 16-year-old body with stiff-man syndrome is described because the condition rarely occurs in this age group. Diagnosis, by appropriate electrodiagnostic studies, is important because stiff-man syndrome is easily treated with high doses of diazepam.

Adolescent↗
PubMedDate not supplied

Infantile spasms in COFS syndrome.

Cerebro-oculo-facial-skeletal (COFS) syndrome is a rare, autosomal recessive syndrome characterized by microcephaly, microphthalmia and/or cataracts, neurogenic arthrogryposis, and multiple congenital anomalies. A term female infant with COFS syndrome who developed infantile spasms at the age of 3 months is reported. The patient had a good response to intramuscular ACTH with disappearance of infantile spasms and resolution of the hypsarrhythmic pattern on electroencephalography succeeded by a slow, synchronous pattern. Modified hypsarrhythmia returned after ACTH therapy was discontinued. Infantile spasms have not previously been reported in association with COFS syndrome and are a potentially treatable aspect of the disease. This patient may add to the clinical spectrum of COFS syndrome or may have a variant.

Abnormalities, Multiple↗
PubMedDate not supplied

Dysphagia due to cervical osteophytes.

A case of a 64-year-old man is presented with painless dysphagia and loud noise on swallowing due to large anterior cervical osteophytes demonstrated on plain radiographs and magnetic resonance imaging accompanied by a brief review of the literature.

Cervical Vertebrae↗
PubMedDate not supplied

Spinal cord toxoplasma lesion in AIDS: MR findings.

Toxoplasma gondii is the cause of the most common opportunistic infection of the brain in AIDS but is extremely rare as the cause of a solitary lesion of the spinal cord. Symptoms are weakness of the lower limbs followed closely by paralysis unless diagnosed and treated early. We present such a case in an intravenous drug abuser with AIDS and emphasize that MRI is the diagnostic tool of choice and that the index of suspicion should be high in immunosuppressed patients.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

Computed tomography in adult-onset epileptic seizures in a city hospital population.

Computed tomography (CT) was performed on 155 patients from a city hospital population who developed seizures after age 20. CT was normal in 58 (37.4%) and abnormal in 97 patients (62.6%). A focal abnormality was seen in 71 patients (45.8%). Lesions potentially correctable by surgery were found in 24 patients (15.4%). As expected, the occurrence of abnormal CTs was higher (73%) in patients with partial seizures. Although CT is undeniably useful in evaluating the cause of seizures, no demonstrable lesion was found in a relatively large number of patients (37.4%).

Adult↗
PubMedDate not supplied

Hyperglycemia presenting with occipital seizures.

Seizures are common in hyperglycemia and are often the first manifestation, particularly in nonketotic hyperglycemia (NKH). Published reports emphasize partial motor seizures almost exclusively. In a 3-year period, we observed three patients in whom occipital seizures, documented by ictal EEG recording, were the initial symptom of hyperglycemia. One patient was mildly ketotic at first. Seizures were visual in two patients and visual and adversive in the third. Seizures regressed with correction of abnormal glucose levels and did not recur during follow-up of less than or equal to 1 year despite discontinuation of antiepileptic drugs (AEDs) in two. Computed tomography (CT) scans did not show correlative abnormalities. Although published reports suggest that frontal lobe structures are particularly susceptible to the epileptogenic effects of NKH, our experience indicates that in NKH epileptic foci may originate in other cortical areas, such as occipital.

Adult↗