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Biomedical subjects

M De La Brassinne

Publications and source records attributed to M De La Brassinne.

9 recordsLinked to original sources
PubMed2005

[Perforation of the nasal septum in cocaine abusers].

Cocaine has been used for centuries for its stimulating and euphoric effects, but it also possesses vasoconstrictive and thrombotic properties. The cocaine-induced lesions depend mainly on the method of administration. In the present case, in which cocaine was nasally inhaled, the perforation of the cartilaginous nasal septum propably result from a combination of factors, including the topical effects and the complications linked to the use of the drug. This clinical observation corresponds to a high level of the progressive nasal pathology associated with cocaine abuse.

Administration, Inhalation↗
PubMed2004

Biological therapies in the systemic management of psoriasis: International Consensus Conference.

Psoriasis is a chronic, immune-mediated disorder that usually requires long-term treatment for control. Approximately 25% of patients have moderate to severe disease and require phototherapy, systemic therapy or both. Despite the availability of numerous therapeutic options, the long-term management of psoriasis can be complicated by treatment-related limitations. With advances in molecular research and technology, several biological therapies are in various stages of development and approval for psoriasis. Biological therapies are designed to modulate key steps in the pathogenesis of psoriasis. Collectively, biologicals have been evaluated in thousands of patients with psoriasis and have demonstrated significant benefit with favourable safety and tolerability profiles. The limitations of current psoriasis therapies, the value of biological therapies for psoriasis, and guidance regarding the incorporation of biological therapies into clinical practice are discussed.

Age Factors↗