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Biomedical subjects

M De Maeseneer

Publications and source records attributed to M De Maeseneer.

At least 19 recordsLinked to original sources

Calcific tendinitis of the longus colli muscle.

BACKGROUND: To the best of our knowledge, only one patient with calcium hydroxyapatite deposition disease (CHADD) of the longus colli muscle has been reported in the otolaryngology literature. METHODS: Clinical findings and results of imaging studies in such a patient are reported. RESULTS: Two particular imaging findings of this disorder are discussed. First, disappearance of calcifications over the short time frame of a week, accompanied by the resolution of clinical symptoms. Second, the presence of an extensive region of high signal intensity extending from the skull base to the lower border of C5, on T2-weighted spin-echo magnetic resonance (MR) images. CONCLUSIONS: Knowledge of the characteristic clinical spectrum and imaging features of this disorder are crucial for a correct diagnosis of this uncommon cause of odynophagia and dysphagia.

Calcinosis

Influence of spondylopathy on bone densitometry using dual energy X-ray absorptiometry.

Spinal cord injury (SCI), as well as other neuromuscular disorders, not only results in osteopenia but also induces various patterns of osseous, articular, and soft tissue alterations. In the spinal column, a variety of abnormalities occur. To evaluate the magnitude of discrepancy of bone densitometry results caused by spondylopathy in SCI patients, we analyzed anteroposterior (AP) radiographs of the lumbar spine [obtained within 1 month of dual energy X-ray absorptiometry (DXA)] in 116 SCI patients for various manifestations of spondylopathy, and matched the result to each vertebral level (L1, 2, 3, 4). The dataset was stratified by individual vertebra (totally 463 vertebrae) as valid (no demonstrable other abnormal density on plain radiograph except osteopenia), abnormal without, and abnormal with hardware. The influence of spondylopathy on bone densitometry results was determined by the analysis of variance (ANOVA) and post hoc analysis. Our results showed that 227 (49%) vertebrae were abnormal. Significant elevation (15%, 15%, 18%, 20%; P < 0.001-P < 0.05) of bone mineral density (BMD; g/cm2) was observed at all levels (L1, 2, 3, 4, respectively), particularly at those abnormal vertebrae without hardware compared with valid (no other abnormal density on radiograph except osteopenia (Table 1). The L4 level was most severely affected. We concluded that in SCI patients, owing to various secondary progressive skeletal abnormalities, particularly neuropathic spondylopathy, can have strongly and significantly elevated vertebral bone densitometry results, which can obscure underlying osteoporosis, leading to misinterpretation and underestimation of fracture risk. DXA, although characterized by improving spatial resolution, cannot replace radiography in establishing the magnitude of this skeletal pathology. Therefore, determination of bone density in this region with corresponding plain radiographs is highly recommended.

Absorptiometry, Photon

Fibrolipomatous hamartoma: MR imaging findings.

OBJECTIVE: To analyze the MR imaging features of fibrolipomatous hamartoma (FLH) of nerves. DESIGN AND PATIENTS: MR imaging studies from six patients (three men and three women) were retrospectively reviewed by three musculoskeletal radiologists. In four patients, a biopsy of the nerve lesion was performed. In two patients, biopsy data were unavailable and the diagnosis was based on the clinical history combined with the MR imaging findings. RESULTS AND CONCLUSION: MR imaging demonstrated fusiform nerve enlargement that was caused by fatty proliferation and thickening of nerve bundles. Nerve bundles appeared as serpentine tubular structures, hypointense on both T1- and T2-weighted images. The degree of fatty proliferation varied among patients. In addition, significant variation in the distribution of fat along the course of the nerves was noted. In three patients, FLH followed the branching pattern of the nerves, a characteristic pathologic finding. In two patients, intramuscular fat deposition (biceps and tibialis posterior muscles) was present. MR imaging findings of FLH are typical, allowing a confident diagnosis. The variation of fatty proliferation among patients and involved nerves as well as the tendency of the abnormalities to follow the branching pattern of the nerves is well demonstrated with MR imaging. FLH may present as an isolated nerve lesion, may be associated with intramuscular fat deposition, or may occur as a feature of macrodystrophia lipomatosa (MDL).

Adult

Evolving stages of lipohemarthrosis of the knee. Sequential magnetic resonance imaging findings in cadavers with clinical correlation.

RATIONALE AND OBJECTIVES: Lipohemarthrosis, the presence of fat and blood in a joint cavity, exhibits several complex layers related to differences in specific component relaxation on magnetic resonance (MR) images. The authors investigated sequential changes in the appearance of lipohemarthrosis of the knee as demonstrated by MR imaging. METHODS: Sequential MR imaging over a 4-day period was performed on two cadaveric knees after intraarticular injection of blood from a volunteer and fat from a cadaveric tibia (50 mL of blood and 25 mL of fat in one knee and 15 mL of blood and 5 mL of fat in the other knee). The authors determined components in the joint based on MR signal behavior. Magnetic resonance imaging examinations of four patients with intracapsular fractures and lipohemarthroses of the knee were reviewed retrospectively. RESULTS: Sequential MR images of cadaveric knees showed serial changes representing progressive formation and lysis of blood clot. Several fluid-fluid levels (globules of fat at the interface between fat and blood) and entrapment of fat were early findings of lipohemarthrosis. Three different fluid levels appeared approximately 3 hours after injection of fresh blood and marrow fat. The 96-hour study demonstrated three distinct levels. CONCLUSIONS: Lipohemarthrosis demonstrates temporal changes on MR imaging related to stages of formation and lysis of blood clot.

Adult

Measurements of cortical thickness in experimentally created endosteal bone lesions: a comparison of radiography, CT, MR imaging, and anatomic sections.

OBJECTIVE: The purpose of this study was to evaluate the accuracy of cortical measurements of experimentally created endosteal cortical lesions and to assess the sensitivity of radiography, CT, and MR imaging in the detection and measurement of such lesions. MATERIALS AND METHODS: Thirty-six cortical lesions were created in three fresh cadaveric femurs. After performing radiography, CT, and MR imaging, we sectioned the specimens in the axial plane. We then measured the remaining cortex at the lesions and the normal cortex adjacent to the lesions on all images and corresponding anatomic sections. The measurements of thickness of the cortex as seen with the different imaging methods and the anatomic sections were compared. Measurements were repeated to evaluate the influence of different window settings on the MR imaging measurements. RESULTS: When measured on radiographs, cortical thickness was overestimated in 58% of lesions. With CT, cortical thickness was overestimated by 0-15% in 94% of all lesions. With MR imaging, cortical thickness was uniformly underestimated by 3-17%. Measurements made on MR images varied according to different window settings. The proton density-weighted sequence yielded the highest sensitivity in the detection of shallow cortical lesions; the T1-weighted spin-echo sequence was the least sensitive of the MR sequences. CONCLUSION: In our cadaveric study, cortical thickness in the presence of endosteal lesions was overestimated on radiographs and CT scans and underestimated on MR images. Measurements derived from MR imaging are strongly influenced by the window setting. MR imaging with the proton density-weighted sequence is the most sensitive for detection of shallow cortical lesions and is more sensitive than CT.

Bone Neoplasms

Low back pain and nuclear medicine.

Low back pain (LBP) is a major cause of disability in many patients during some time of their lives. In this article the role of nuclear medicine, and more in particular the role of single photon emission tomography (SPECT), in the investigation of LBP is discussed by reviewing the literature. Because of the improved anatomical localization of lesions in the vertebral body when up-to-date SPECT is used, this technique is a powerful imaging modality in patients with LBP. Bone scintigraphy therefore can contribute significantly in the diagnosis of patients with LBP. In cases where conventional radiological techniques fail to elucidate the cause of LBP performing a bone scintigraphy with SPECT should strongly be recommended.

Diagnosis, Differential

Ventral sacroiliac ligament. Anatomic and pathologic considerations.

RATIONALE AND OBJECTIVES: The ventral sacroiliac ligament (VSL), which bridges the sacroiliac (SI) joint anteriorly, has been described as an important stabilizing structure of the joint, but no data exist regarding its assessment with routine and advanced imaging methods. The authors determine the imaging appearance of the normal and abnormal VSL using close anatomic-histologic-imaging correlation. METHODS: Eight and 10 cadaveric SI joints were examined with magnetic resonance imaging in axial and coronal planes, respectively; and in four computed tomography scanning in both planes was obtained. Anatomic sectioning with histologic correlation at levels corresponding to those of imaging planes was performed. Representative examples of diseases that produce abnormalities of the VSL and connective tissue about the SI joint were reviewed. RESULTS: Magnetic resonance images showed the VSL-anterior capsular complex as a hypointense, linear, or minimally curved structure of approximately 2 mm thickness traversing the SI joint anteriorly. The VSL could not be separated from the anterior joint capsule by imaging studies, but such differentiation by histology could be determined based upon the orientation of its collagen fibers. Any disease process that affects the ligament or the site of ligamentous attachment to bone produces characteristic imaging alterations.

Aged

Jejunal stromal tumor.

A case of jejunal stromal tumor is reported. Clinical findings included melena, syncope, and palpable abdominal mass. CT scans showed an abdominal mass with characteristics simulating an intra-abdominal abscess.

Aged

Squamous cell carcinoma of the urethra: ultrasonographic findings.

Urethral carcinoma is a rare neoplasm and only recently MR imaging has been applied to evaluate these tumors. Ultrasonography has mainly been used in the evaluation of urethral strictures. In the present paper a patient with squamous cell carcinoma of the urethra is reported and findings on ultrasonograms are described. Ultrasonography depicted the intraluminal tumor, in contrast to retrograde urethrocystograms, which appeared inconspicuous.

Aged

Hand and foot acrometastases in a patient with bronchial carcinoma.

The occurrence of acrometastases in a patient with bronchial carcinoma is rare but well known. Lung tumours however seldom give rise to foot metastases. The simultaneous occurrence of both hand and foot metastases in the same patient is extremely rare. We describe a patient with epidermoid epithelioma of the lung who developed such lesions as the first manifestation of metastatic disease.

Bone Neoplasms

A rare cause of rickets in a young child.

We present a case of nutritional rickets in a young child due to a macrobiotic diet. The child presented with important thoracic deformation and breathing difficulties. Plain radiographs appeared to be an excellent method for the diagnosis and follow-up of the bony lesions in this disorder. We describe the typical bony abnormalities related to this relative rare disease.

Calcium, Dietary

[Endarterectomy by division of the internal carotid artery].

The literature reports superior results with patch angioplasty compared to direct suture for the restoration of the carotid artery after endarterectomy through a longitudinal arteriotomy. With the technique presented here access to the arterial lumen is gained through an oblique division of the internal carotid at its origin. After endarterectomy this vessel is reanastomosed to its origin on the common carotid. This oblique suture does not induce any stenosis. This technique is easily reproducible. In a prospective randomized study, comparing its results to saphenous vein angioplasty, no significant difference was found on mortality, morbidity and recurrent stenosis. With this technique, the saphenous vein can be preserved for other vascular reconstructions.

Carotid Artery, Internal

Detecting clustered microcalcifications in the female breast: secondary digitized images versus mammograms.

We compared the detection of clustered microcalcifications by means of conventional mammograms and by means of secondary digitized images with a spatial resolution of 2048 x 1684 pixels and a contrast resolution of 12 bit. A Receiver Operating Characteristic (ROC) study was carried out using a cadaver breast showing phantom microcalcifications. A set of 100 mammograms was evaluated by two experienced senior radiologists. The ROC scores obtained with the digital images were 10% lower than those obtained with the conventional images. This difference however does not reach statistical significance. The use of a digital zoom function based on pixel duplication is also investigated. This zoom function does not produce a change in the diagnostic accuracy of the digital method. Attention is also paid to the advantages and disadvantages encountered by the radiologists when working on the digital viewing system. The most important drawback seems to be that it is considerably more time consuming than the conventional procedure, and this is especially due to the long loading time of the images and to the absence of window and level preselections.

Breast Diseases

The ultrasound aspect of the skin and subcutaneous fat layer in various benign and malignant breast conditions.

In a series of 260 consecutive X-ray mammography examinations in symptomatic patients, 25 patients proved to have breast cancer, and 41 had various benign breast conditions. In the 66 patients with abnormal mammograms a real-time ultrasound examination with a 7.5 MHz linear array transducer and a fluid offset pad was performed. This paper focuses on the ultrasound aspect of the skin and the subcutaneous fat layer in various benign and malignant breast conditions. In most of the malignant tumors studied as well as in cases of fat necrosis and breast abscesses, the following ultrasound signs were encountered: discontinuity of the sharp echogenic subcutaneous specular reflector, thickening of the skin, and locally increased echogenicity of the subcutaneous fat layer. In breast cancer these signs were seen in some patients with small tumors, in deeply located tumors as well as in patients with no skin retraction on clinical examination. The differential diagnosis between cancer and benign breast tumors cannot be based upon the ultrasound aspect of the skin and subcutaneous fat layer alone. X-ray mammography as well as clinical criteria and anamnestic factors should be used for the diagnosis of breast abscesses (calor, rubor, tumor, dolor) and for the diagnosis of fat necrosis (surgery, trauma).

Abscess

Closure of the internal carotid artery after endarterectomy: the advantages of patch angioplasty without its disadvantages.

We present an original technique which precludes narrowing of the internal carotid artery after simple closure of a longitudinal arteriotomy for endarterectomy. Derived from the technique used to treat excess length of the internal carotid artery, this procedure includes the following steps: (1) division of the internal carotid artery at its base; (2) slitting the carotid artery until reaching the distal part of the plaque; (3) endarterectomy of the internal carotid and common carotid-external carotid axis; and (4) reimplantation of the internal carotid into its ostium, enlarged to the new size of the divided carotid artery. It has been possible to use this technique in eight consecutive cases. Postoperative arteriograms and duplex scanning have shown that anatomic and functional results were excellent. Presently, this technique has our preference in the surgical treatment of atheromatous stenoses of the internal carotid artery.

Anastomosis, Surgical

Pseudoaneurysm of the posterior tibial artery as an early complication after Fogarty catheter thrombectomy.

After angioplasty of the superficial femoral artery at Hunter's canal in a 65-year-old woman thrombosis developed and femoropopliteal bypass grafting was necessary. Four weeks later the graft occluded, successful thrombectomy was performed with a Fogarty catheter and the patient heparinised. Three days later a pseudoaneurysm developed on the posterior tibial artery which was excised and the artery which was longitudinally torn repaired with a vein graft giving good functional results. Complications after Fogarty balloon catheter thrombectomy are relatively rare but Pseudoaneurysms can occur after perforation or rupture of smaller vessels.

Aged