Lesion of the basal ganglia and surgery for Parkinson disease.
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Biomedical subjects
Publications and source records attributed to M DeLong.
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OBJECTIVE: To optimize the accuracy of initial stereotactic targeting for movement disorders surgery, we performed stereotactic localization of the internal segment of the globus pallidus (GPi) and subthalamic nucleus (STN) using magnetic resonance imaging protocols in which the borders of these nuclei were directly visualized. METHODS: Fifty-one consecutive cases using the pallidal target and six using the subthalamic target were studied. Localization of these nuclei was performed using the Leksell stereotactic head frame and inversion recovery sequences (GPi) or T2-weighted spin echo sequences (STN). Targeting accuracy and individual variation in the spatial coordinates of these structures were independently measured by identification of nuclear boundaries during multiple microelectrode penetrations. RESULTS: The lateral and vertical coordinates of an atlas-defined point in the GPi, with respect to the line between the anterior and posterior commissures, was highly variable. Initial targeting the GPi based on direct visualization of the target boundaries (external medullary lamina and optic tract) resulted in greater precision than would be expected using fixed anterior and posterior commissure-based coordinates. Initial targeting the STN using magnetic resonance imaging was sufficiently precise to place the initial microelectrode penetration within STN in all six cases. CONCLUSION: Magnetic resonance imaging-based initial stereotactic targeting of the GPi, based on direct visualization of the target boundaries, is useful to improve target accuracy over that of purely indirect anterior and posterior commissure-based targeting methods. Initial targeting of the STN was reliably accomplished by direct visualization. However, there remains sufficient variability that the final target location in both GPi and STN required electrophysiological mapping in all cases.
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One hundred seventy-two undergraduate women responded to twelve sets of stimuli consisting of a constant jacket silhouette varying proportionally in components of lapel, yoke, and pocket details. Using a 9-point scale in Likert format, the subjects were asked to respond to questions comparing the jacket stimuli of each set in terms of same/different, unattractive/attractive, unwearable/wearable, unfashionable/fashionable, not acceptable/acceptable, and dislike/like. This jacket was varied in its component parts to correspond to proportions currently available in Petite and Misses size apparel. Analysis indicated that subjects detected differences in proportions of garment details within the context of a petite jacket silhouette and preferred proportions adjusted to the smaller size.
Traditional linear measurements (lengths and circumferences taken over the body surface with a tape measure) were compared with measurements of frontal and lateral view photographs for usefulness in determining pattern dimensions for the upper torso of the female body form. The statistical regression models developed indicated that, while linear measurements provided slightly more accuracy in predicting a few of the pattern dimensions, the photographic measurements were more accurate in predicting others, particularly pattern angles. Photographic measurements hold promise as an alternative to the more intrusive linear measurements for predicting pattern dimensions.
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