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Biomedical subjects

M Delanghe

Publications and source records attributed to M Delanghe.

5 recordsLinked to original sources

Serotyping and phage typing to identify Enterobacter cloacae contaminating total parenteral nutrition.

The origin of an outbreak of Enterobacter cloacae septicemia in six surgery patients was traced down to the total parenteral nutrition production line. While the endproduct of the production line was sterile, Enterobacter cloacae and other bacteria were detected on different tabs and tubings of the line. It is believed that the bacteria were transferred from the tabs to a few bags of the total parenteral nutrition in one batch by touch contamination. Serotyping and phage-typing of the clinical isolates revealed that five of the patients' strains were identical.

Bacteriophage Typing↗

Pseudomonas pickettii as a cause of pseudobacteremia.

An outbreak of pseudobacteremia caused by Pseudomonas pickettii biovariant 1 is reported. The common source was the aqueous chlorhexidine solution prepared by the hospital pharmacy. The contamination problem caused by the antiseptic solution was eventually solved by a series of preventive measures.

Adult↗

Effect of electrolytes in the presence of some trace elements on the stability of all-in-one emulsion mixtures for total parenteral nutrition.

In a previous study we showed that the 'all-in-one' emulsion mixtures investigated for total parenteral nutrition are stable for 1 month when kept in ethylene vinyl acetate polymer (EVA) bags and refrigerated at 4 degrees C. Analogous experiments were performed with the addition of two different solutions of trace-elements: one was prepared in the pharmacy while the other was commercially obtained (Addamel, Kabi Vitrum). A Coulter counter TA II with a 30 microns orifice was used for globule size measurements. Particles with diameters ranging from 0.6 up to 16 microns were measured. No significant changes in particle size were noticed during storage and the routine addition of trace elements to the 'all-in-one' mixtures was thus possible. These emulsions can be stored without stability problems for at least 8 days.

Drug Stability↗