PubMed HealthSearch

Biomedical subjects

M Delapierre

Publications and source records attributed to M Delapierre.

4 recordsLinked to original sources

Feasibility of measuring oxygen tension in uterine cervix carcinoma.

Cellular hypoxia is a cause of radioresistance. The oxygen tension (pO2) in normal tissues and in tumours can be measured by polarography. In this feasibility study we have measured the tissue pO2 of 10 patients suffering from uterine cervix carcinoma, using the Eppendorf histograph. The measurements were performed at the time of the brachytherapy after external radiotherapy. The machine was found to be reliable and no adverse effect was noted. The mean pO2 values in tumours were lower than those of normal tissues.

Adult

Prospective comparison of ultrasound and computed tomography in the evaluation of the size of the uterus: can these methods be used for intracavitary treatment planning of carcinoma of the uterus?

A prospective evaluation of computed tomography and ultrasound was performed on 34 patients with Stage I and II endometrial carcinoma. All patients underwent immediate surgery following intracavitary treatment directed to vaginal mucosa. Pathologic measurements of the uterus were compared to those obtained by imaging technologies. The results of the study suggest that all but height measurements were rather accurately determined by both ultrasound and CT scan. However ultrasound was significantly better in determining the size of the cervix. Therefore ultrasound measurements could be used routinely for intracavitary treatment planning in endocervical carcinoma and endometrial carcinoma.

Brachytherapy

[X-ray computed tomography of cancers of the uterine body (stages I and II). Anatomopathologic correlations. Apropos of 25 cases].

Twenty-five patients with endometrial cancer of body of uterus were examined by CT before and after intravenous administration of contrast medium. Hypodensity was noted before injection and was accentuated after injection in 4 cases, was observed after injection only in 9 and was totally absent in 12 cases. Comparison of findings with results of examination of frozen specimens indicated lack of correlation between size of tumor and depth to which myometrium was invaded, and results of CT imaging.

Adenocarcinoma