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Biomedical subjects

M Deller

Publications and source records attributed to M Deller.

At least 19 recordsLinked to original sources
PubMed1992

[Prevention of coronary heart disease by therapy of hyperlipidemia. Between cholesterol hysteria and therapeutic realism].

OBJECTIVES: The present paper is intended to provide an overview of the arguments for and against drug treatment of hyperlipidemia. MAJOR TOPICS: An argument in support of lipid-lowering prophylactic and therapeutic programs is the close relationship between lipid levels and coronary heart disease, which has been documented both epidemiologically and by interventional studies. Arguments against comprehensive treatment of hyperlipidemia have to do with the fact that although large interventional studies have shown a reduction in mortality from coronary heart disease, there has been no reduction in overall mortality. Of decisive importance for the decision to apply lipid-lowering treatment is the overall risk profile of the patient concerned. This includes not only pathological lipid levels, but also numerous other factors that must be taken into account when considering the indication. CONCLUSIONS: Whether to initiate lipid-lowering treatment or not should be determined on the basis of the individual patient's risk profile, with additional consideration being given to age and sex.

Cholesterol↗
PubMed1991

[Short- and intermediate-term angular results of Cüppers retro-equatorial myopexy, with or without additional simultaneous recession].

79 variable esotropias underwent bilateral "Fadenoperations". In the first group, the posterior fixation has been performed alone. In the second series, conventional symmetrical recessions of the medial recti have been performed during the same procedure. Two further additional weakening techniques are compared in the last group: anterior medial tenotomies and the so-called "stretch effect". Concomittant recessions considerably enforced the amount of angle reduction for distance and near without affecting precision, predictibility and stability of the results. Tenotomies and stretching procedures were followed by inconstant results.

Accommodation, Ocular↗
PubMed1988

Why should surgery for early-onset strabismus be postponed?

The author presents a continued study of 82 cases of pseudoparalysis of the bilateral rectus muscles in early-onset convergent strabismus following early surgery. Up to 10 years after surgery motor results show that 72% of cases remain within +/- 10 prism dioptres after a single surgical procedure. Sensorial findings corroborate the results of other authors' studies in that binocular association is only achieved in those patients where surgery was carried out at a very young age, not older than 1 year. Surgical procedures consisting of bimedial rectus recession with retroequatorial myopexy are described and the development of alphabetical syndromes and dissociated vertical divergence discussed. The evolution of refraction in these cases is also shown.

Age Factors↗
PubMed1985

[Endocrine ophthalmopathy].

The author lists the various ocular complications of Graves' disease, ranging from the very mild, which need no treatment, to those which require medical treatment, usually with cortisone, sometimes in combination with immunosuppressors. The relatively slight oculomotor problems can sometimes be alleviated with prisms. More serious complications require surgery of the extraocular muscles, which is not discussed in this paper.

Adult↗
PubMed1978

[The surgical treatment of superior oblique paralysis (author's transl)].

The line of treatment drawn out by Malbran more than 20 years ago has lost none of its standing. However, although the main principles are still valid, the surgical protocol should be modified in view of the evolution of the surgical concept and technique for which we are indebted to Cüppers. The so-called "thread operation", which the author proposes to call the "Retroequatorial Myopexy of Cüppers" brings a decisive progress. Combined with the primary effect on the paralysis muscle, it also elegantly solves the three problems of this paralysis, namely hyperphoria, excyclophoria, and muscular incomitance. The ideal surgical plan includes now a Superior Oblique Tuck of the affected muscle, with a Retroequatorial Myopexy of the Inferior Rectus of the sound eye, either in the same operation or separately. The muscle weakening procedures by the traditional recession should be avoided.

Humans↗