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Biomedical subjects

M Delplace

Publications and source records attributed to M Delplace.

3 recordsLinked to original sources

[Oscillating algorithm in medical diagnosis : alternation of flow-charts and diary programs].

26 programs of paraclinical tests for inpatients were written in diary form. Conditions of use were clearly defined with emphasis on optimal utilization of the first two or three days of the stay. Nine diaries are presented as examples. In order to reconcile various clinical, logical and economic requirements, the algorithm should oscillate between the flow-chart and the diary. For clinical evaluation, the flow-chart, completed by a health questionnaire, is satisfactory. But, for prescription of the first paraclinical tests, the diary appears more efficient under the specified conditions of use. The next step should then be a flow-chart, and so on. Flow-charts and diaries may be provided separately, each clinician having the possibility of alternating from one to the other, according to findings and local conditions.

Diagnosis

[Renal manifestations of Sjögren's syndrome. Review of the literature starting with a case].

Sjögren syndrome, characterized by lymphocytic proliferation and drying up of exocrine secretions ("sicca syndrome") due to glandular destruction, is well known for it's ocular and salivary localizations. However, other glandular epithelia (bronchial, vaginal . . .) or parenchyma (such as the kidney) may be involved. Damage to the kidney is rarely prominent; it is usually discovered late in the course of the disease. Moreover the renal manifestations are multiple and variably associated: diabetes insipidus, tubular acidosis, Fanconi syndrome, tubular and interstitial nephritis, and glomerulonephritis.

Acidosis, Renal Tubular