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Biomedical subjects

M Denaut

Publications and source records attributed to M Denaut.

10 recordsLinked to original sources

[Unilateral pulmonary oedema after re-expansion (author's transl)].

The authors report three cases of unilateral pulmonary oedema following the re-expansion of a spontaneous pneumothorax. The importance of the duration of the pneumothorax and the use of too negative pressure while re-expanding the lung were both underlined. The different physiopathological hypotheses responsible for the appearance of pulmonary oedema were discussed, notably altered mechanical properties of the lung and alveolar-capillary permeability. The numerous precautions to take to avoid the appearance of oedema, as well as the therapeutic measures to adopt for severe pulmonary oedema were reviewed.

Adult↗

Pulmonary function in metastatic carcinoma to the lung.

Pulmonary function tests, at rest and during exercise, were performed in nine patients with metastatic carcinoma to the lung. The results are compared to the usual characteristics of diffuse interstitial fibrosis. Differences also occur between the pure multiple metastases pattern and the lymphangitic one. Literature on this topic is reviewed.

Adult↗

[Regional distribution of ventilation and perfusion in the beginning chronic bronchopneumopathies].

The regional distribution of lung ventilation and perfusion was determined in five normal subjects and in patients suffering from chronic bronchitis or asthma with variable functional repercussion, and also in some cases of beginning lung emphysema. The system of detection under use is a scanning camera coupled with a computer. In the case of chronic bronchitis or of asthma, there exists, the more often, a redistribution of lung ventilation and perfusion from the bases towards the vertices. The alterations are less evident in the cases of emphysema submitted to study. The limits of the method are object of discussion. Its application to the early detection of bronchopneumopathies does not appear as possible.

Adult↗

Double-blind comparison of the respiratory effects of parenteral lorazepam and diazepam in patients with chronic obstructive lung disease.

The effects on the respiratory function of two tranquillising drugs, lorazepam and diazepam, have been compared in 20 patients with chronic obstructive lung disease. Both drugs induce a respiratory depression (decrease in tidal volume and minute ventilation with acceleration of the respiratory frequency) with slight respiratory acidosis, but lorazepam causes no significant hypoxemia and has a shorter duration of action than diazepam. Nevertheless, if tranquillisers are indicated in such patients, they have to be used with care.

Acidosis, Respiratory↗