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Biomedical subjects

M Dewan

Publications and source records attributed to M Dewan.

23 records · Page 2Linked to original sources
PubMed1987

Respiratory sensitivity to carbon dioxide in schizophrenia.

Respiratory sensitivity was evaluated in 10 patients with schizophrenia and 10 normal control subjects utilizing a rebreathing system and measurements of the changes in the mouth occlusion pressure in 100 ms and ventilation in response to the increase in end-tidal PCO2 (PetCO2). Although ventilation response was similar in both groups, we noted that the occlusion pressure response was more variable (coefficient of variability, CV = 17.5%) and the correlation coefficient (r = 0.75 +/- 0.13) lower in the patients with schizophrenia compared to controls (CV = 4.6%; r = 0.90 +/- 0.04). Apnea threshold was also lower in patients with schizophrenia (29.03 +/- 12.73 Torr, mean +/- SD) compared to controls (39.5 +/- 4.5 Torr). Furthermore, schizophrenia patients showed a significant positive and negative correlation between occlusion pressure response and age (r = 0.73; p less than 0.001) and estimated duration of schizophrenia (r = 0.65; p less than 0.05). We conclude that the apnea threshold is lower and the respiratory sensitivity to CO2 is more variable in patients with schizophrenia compared to normal subjects.

Adult↗
PubMed1982

On fear in the countertransference.

The rational and irrational aspects of fear in the countertransference will be discussed. Arguments are presented for the potent force of fear in personality development and psychotherapy hitherto underemphasized in the literature. Manifestations of unacknowledged fear in clinical settings are identified and discussed. Recommendations are made for dealing with rational and irrational fears. These include supervision and interpretation in the case of irrational fear and effective security in the case of rational fear.

Adult↗
PubMedDate not supplied

A direct comparison of the defense mechanisms of nondepressed people and depressed psychiatric inpatients.

This report presents a direct comparison of defensive styles (as measured by the Defense Mechanisms Inventory [DMI]) in a sample of depressed psychiatric inpatients and samples of nondepressed male and female normative groups. Consistent with the "depressive realism" literature, nondepressed men and women were more likely than their depressed counterparts to bias their perceptions in an overly cheerful, optimistic direction. Counternormative sex differences were also found. Depressed men were more likely to use internalizing defenses and depressed women were more likely to use externalizing defenses than their respective nondepressed comparison groups. Overall, as has been speculated, there was a relationship within depressed subjects between depression severity and the amount of negatively biased self-perception.

Adult↗
PubMedDate not supplied

Bronchial carcinoid tumours in southern Saudi Arabia.

Clinical presentation, pathology, surgical management and follow-up of ten bronchial carcinoid tumour (BCT) patients are described. There were five male and five female patients with age range between 5 to 85 years (mean 39.2 +/- 21.5, SD). Pathology revealed BCT on the right side in seven and on left side in three patients. The tumour was an incidental finding in four while the other six had respiratory symptoms. Cough was present in all of the later group and hemoptysis was present in four patients. Recurrent chest infections were seen in two patients. Symptoms ranged from 1 week to 15 years. Successful surgical resection was done in nine with the longest follow-up of 80 months (mean: 23 months +/- 26.3, SD) without recurrence or metastasis. Histopathological examination of these tumours revealed classical morphological features in all but one case. Grimelius stain positivity for argyrophilia confirmed the diagnosis in all the patients in this study. Electron microscopic examination was done in patient no. 9 which showed atypical morphological features and neurosecretory granules. BCT may present like pneumonias or bronchial asthma. Although BCTs have low-grade malignancy, early diagnosis and surgical resection yield curative results almost in all cases.

Adolescent↗