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Biomedical subjects

M Diouf

Publications and source records attributed to M Diouf.

At least 19 recordsLinked to original sources

[Emergency reimplantation of the tongue after complete traumatic amputation].

Complete traumatic amputation of the tongue is very exceptional, the intra-oral position generally protecting the tongue. Most reported cases of trauma have involved partial section with satisfactory results after simple suture. Complete amputation of a portion of the tongue occurred in a 12-year-old boy during a fight. The fragment of the tongue was brought to the emergency unit. It was placed in heparinated saline solution and replanted successfully three hours after the trauma. Plastic surgery of the oral cavity was also performed to repair laceration injuries. The postoperative period was uneventful and the tongue regained vitality and normal motion. There was just a slight retraction. Replantation of the tongue after complete section may not be successful but should be attempted when possible.

Amputation, Traumatic↗

[Role of Anopheles melas Theobald (1903) on malaria transmission in a mangrove swamp in Saloum (Senegal)].

From June 1995 to January 1998, entomological studies carried out in five villages located in the Delta's Saloum have allowed to better understand the contribution of An. melas Theobald (1903) to malaria transmission in mangrove swamp. Among the five villages studied, three of them (Simal, Djilor and Marlothie) located along the Saloum river, are colonised by An. arabiensis; the two others (Djifere and Diakhanor) located between the sea and the river, are colonised by An. melas. During the rainy season and at the beginning of the dry season, An. melas and An. arabiensis are sympatric. The ratio of An. melas/An. arabiensis increases when we go closer the coast where An. melas becomes quite exclusive. When An. melas is predominant, endophagy, endophily and anthropophily are very marked. The parturity rates are lower in An. melas than in An. arabiensis. In the predominance area of each species, transmission is on the same level. During the period of sympatry, An. arabiensis is responsible for the transmission and when it is absent, An. melas carries on. Transmission occurs from July to March with a maximum at the beginning of the dry season. In the villages of the mangrove swamp, its prolongation until the middle of the dry season is due to An. melas.

Animals↗

Two new species of Nippostrongylinae (Nematoda, Trichostrongylina) parasites of Cricetomys gambianus and Arvicanthis niloticus (Muridae) from Senegal.

Two new Nippostrongylinae (Heligmosomoidea, Heligmonellidae) originating from Senegal are described. Heligmonina bioccai n. sp., a parasite of Cricetomys gambianus (Cricetomyinae) found in the surroundings of Dakar and Neoheligmonella bai n. sp., a parasite of Arvicanthis niloticus (Murinae) from the Province of Richard Toll. H. bioccai n. sp. is related to H. hybomysi (Durette-Desset, 1966) a parasite of Hybomys univittatus from the Central African Republic by some characteristics of the caudal bursa and of the synlophe. They are the only two species with the same pattern of caudal bursa: type 1-3-1 for the right lobe, 2-3 for the left lobe, and with the same number and disposition of the cuticular ridges at mid-body in the female. The two species are differentiated by the size (three times smaller in H. hybomysi), the ratio of spicule length on body length (7.6% versus 17% in H. hybomysi) and by a different synlophe in male and posterior part of female. N. bai n. sp. is differentiated from the closely related species N. dielmensis Diouf, Bâ and Durette-Desset, 1997, also a parasite of Arvicanthis niloticus from Senegal by rays 8 arising asymmetrically on the dorsal ray and by the deirids situated at the same level as the excretory pore.

Animals↗

[Trichosomoides nasalis Biocca & Aurizi, 1961 and T. spratti n. sp. (Nematoda: Trichinelloidea), from the nasal cavity of murids].

The nematode parasite of the nasal mucosa of rodents, Trichosomoides nasalis, is common in the murid Arvicanthis niloticus, in Senegal. The morphological study of this material allowed us to augment the original description, made with specimens recovered in Italy from Rattus norvegicus. This analysis shows that specimens from Rattus fuscipes in Australia, which had been identified to this species, represent a distinct species (smaller, with an average of five intrauterine males per female instead of one), which we name T. spratti n. sp.

Animals↗

Pterygodermatites (Mesopectines) senegalensis n. sp. (Nematoda, Rictulariidae), a parasite of Mastomys huberti (Rodentia, Muridae) in Senegal.

Pterygodermatites (Mesopectines) senegalensis n. sp. (Nematoda: Rictulariidae) is described from Mastomys huberti in Senegal. It differs from other species of the subgenus by the morphology of the head, which exhibits 4 simple cephalic papillae and a nearly axial buccal opening, the length of the spicules, the number of precloacal cuticular formations, and the absence of cephalic apophyses.

Animals↗

[Zoophagia and alternative host selection of the marlaia vectors in Senegal].

Blood-engorged females of An. gambiae s.l., An. funestus, An. pharoensis and An. rufipes caught resting indoors were tested (precipitin or enzyme-linked immunosorbent assay) to determine the source of bloodmeal. The species of the An. gambiae complex fed mainly on human hosts in all prospected areas, except in those of the mid Senegal river valley where an important zoophily was observed within and near the irrigation zone. Among 4,597 blood-engorged females of An. gambiae s.l., 29% fed on cattle with 7.5% of mixed boodmeals, mainly human-bovine or human-equine. The presence of cattle, culicid population densities and individual mosquito safety devices were the most determinant factors of animal deviation. Blood of most domestic animals was found in the stomach of collected females, but according to areas, bovines and equines were the main hosts for zoophilic females of An. gambiae s.l. Females of An. funestus collected in the middle-west were more anthropophilic than those collected in south-eastern areas. An. pharoensis was most prevalent in the Senegal river delta where it was found to be very anthropophilic. An. rufipes was strongly endophilic but exclusively zoophilic in all prospected areas.

Animals↗

A comparison of thick smears, QBC malaria, PCR and PATH falciparum malaria test trip in Plasmodium falciparum diagnosis.

Blood samples from 182 patients presenting at the out-patient clinic in Richard-Toll. Senegal were analysed by Thick smear microscopy, the QBC, PCR and the new dipstick PATH Malaria assay which detects the histidine rich protein II antigen of Plasmodium falciparum. Thick smear microscopy was used as the reference method. Sensitivity, specificity, predictive positive and negative values were 100%, 83.6%, 93.4% and 100% QBC respectively; 100%, 72.7%, 89.4% and 100% for PCR; 96%, 92.7%, 96.8% and 91% for the PATH assay. PATH assay failed to detect one positive sample with Plasmodium malariae. Assays were also compared with regard to the expense of equipment and reagents and speed and ease of use. The rapid PATH assay can be performed with minimal training and may be specially useful in areas where P. falciparum is the predominant malaria species, in epidemic malaria regions, and where skilled microscopy is not readily available.

Ambulatory Care Facilities↗

[Heterogeneity of chloroquine resistant malaria in Senegal].

In order to evaluate the in vivo efficacy of chloroquine in the treatment of P. falciparum malaria, studies have been carried out in Richard-Toll, Fatick and Tambacounda, 3 areas where dynamics of transmission, population movements, as well as prophylactic and curative practises are different. Failure rates in treatment were 13% in site 1 (Richard-Toll) where medical pressure and population movements are high. In sites 2 and 3 (Fatick and Tambacounda), the failure rate was 3%. Even if medical pressure is lower in the latter site (Tambacounda), the higher transmission could be a factor in the spreading of resistance. A surveillance system and better use of chloroquine must be undertaken.

Adolescent↗

Diagnosis of Plasmodium falciparum malaria using ParaSight F, ICT malaria PF and malaria IgG CELISA assays.

A battery of sixty-six blood samples from Senegal was analysed by the ParaSight F test, the ICT Malaria PF and the Malaria IgG CELISA. These three assays detect the histidine rich protein 2 antigen of Plasmodium falciparum. Thick smear microscopy was used as the reference method. Sensitivity, specificity, predictive positive and negative values were respectively 89%, 100%, 100%, 88% for the ICT; 86%, 93%, 94%, 85% for the paraSight and 88%, 87%, 88%, 87% for the Malaria IgG CELISA. The three assays failed to detect two positive samples with P. ovale and P. malariae. Assays were also compared with regard to the expense of equipment and reagents and speed and ease of use. The rapid ICT and ParaSight F test can be performed with minimal training and may be specially useful in areas where P. falciparum is the predominant malaria species, in epidemic malaria regions, and where skilled microscopy is not readily available.

Adolescent↗

Subulura saloumensis n. sp. (Nematoda, Subuluroidea) from four species of rodents in Senegal.

A new species of the genus Subulura is described from 4 new rodent hosts: Arvicanthis niloticus, Mastomys erythroleucus, Mastomys huberti, and Tatera gambiana. Subulura saloumensis n. sp. differs from the congeneric species by the morphology of its head. the absence of buccal lobes, the length of right and left spicules, the absence of caudal alae, and the existence of a caudal papillae with a sensorial bristle. The latter, which we observe for the first time in specimens gathered from M. huberti, has never previously been described in a species of the genus Subulura.

Animals↗

[Malaria in the southern sanitary district of Dakar (Senegal). 2. Entomologic data].

To complete a parasitological survey, entomological prospections were carried out in the southern sanitary District of Dakar, the most urbanized of the city and which includes the city centre and the oldest administrative districts. The prospections took place between June 1994 and May 1995 in sites 1.5 km apart, and distributed in such a manner that they covered the entire area. On a monthly basis, female Culicidae were collected in each site at night on human volunteers, followed the next day by the collection of early morning residual fauna in 10 bedrooms located in district concessions. For a total of 308 collections at night on human volunteers and from 1,510 rooms for the residual fauna, 22,901 female Culicidae were caught of which 167 anopheles, corresponding to 0.7%, the remaining 98.5% being Culex quinquefasciatus. This was the species that thus explained the mosquito-nuisance of which the inhabitants of the southern District complained during the period of survey. The female anopheles collected belonged to 2 species, An. arabiensis for 97.6% of those caught and An. pharoensis for 2.4%. An. arabiensis were very slightly represented in the southern District with a density of aggressive females of 0.26 bite/man/night (B/M/N) and a density per room of 0.05 female. The aggressive populations appeared to be relatively important only at the end of the rainy season (September-October) with an average of 0.65 B/M/N in sites located at the periphery of the district with a maximum of 1.33 B/M/N. The highest density of endophilic females registered at the end of the rainy season was 0.1 and its highest value in a given site was 0.36 female/room. The parturity rate of aggressive females was 43.5% and those collected in houses of 84% with an anthropophilic index of 0.98. None of the dissected An. arabiensis females (77.3% of those collected) was a carrier of Plasmodium sporozoites and the circum-sporozoite antigen was not found. A very weak density of An. arabiensis and absence of plasmodial infection among dissected females favoured the absence of malarial transmission in the southern District for the period considered. However malaria transmission could not be absolutely ruled out given the presence of hematozoa carriers, as was revealed by the longitudinal follow-up of a cohort carried out concurrently with the entomological prospections of whom some were residents having declared permanent residence in the city for over two years. This entomological data explain the results of the afore mentioned parasitological survey which, with a registered plasmodic index of 0.3%, means that the southern District can be considered as non endemic. The area is however exposed to the risk of epidemic malaria following an important proliferation of anopheles, which is always possible after heavy rains and flooding and/or an important immigration of persons coming from regions of high malarial endemicity.

Animals↗

Gongylonema madeleinensis N. sp. (Nematoda:Spiruroidea), from Mastomys erythroleucus (Rodentia) from a Senegalese island.

A new species of gongylonematid parasites of the rodent Mastomys erythroleucus is described. Gongylonema madeleinensis n. sp. differs from the other species of the genus by the size of its eggs and spicules-gubernaculum complex, the form and distribution of its cuticular scutella, and the absence of a pore on its cephalic plate. After examination of the esophageal content of 270 continental and 29 insular rodents, G. madeleinensis n. sp. seems to be endemic to the island "des Madeleines" near Dakar, Senegal.

Animals↗

[Intestinal parasitic diseases and tinea of the scalp in Dakar school population: influence of environmental factors on the infestation level].

We carried out a study during February 1993 in a french and three coranic schools in order to evaluate the incidence of the economical level on the prevalence of intestinal parasites and tinea's scalp. Infection rate by intestinal parasites were 67.4% and 84% respectively in french and coranic schools with significant differences: X2 = 10.8. Infection rate by dermatophytes were 10.6% and 48.8% respectively in francophone and coranic schools with significant differences: X2 = 29.3. Ascaris was predominant through all ages in coranic schools, while amaeba were the main parasites in the upper ages in the french school. Bad environmental features observed in coranic schools as well as in popular areas are risk factors to the infection and contribute to increase the prevalence of intestinal parasitic diseases and tinea's scalp.

Child↗

[Cooperation. Education/clinical practice in primary health care, in Dakar].

Senegal recognizes universal health care for all, with health care policies that give priority to low income rural neighborhoods and maternal/child health. However, the reality is that official health care services cover only 13 per cent of the rural population. A collaborative program between the University of Montreal School of Nursing and the Centre for Higher Education in Dakar Senegal, illustrates the innovativeness of international co-operation. The goal of the program is to provide nursing education for students in primary health care and midwifery. The nursing students in this program would care for the residents of the town of Tivaouane, with emphasis on maternal/child health care. Nursing students from three schools in Dakar completed the clinical phase of the program working with health care professionals and the residents of Tivaouane. The program has four components: education, clinical, research and women's health. The education component consists of a revision of the current nursing program, a primary health care curriculum, and continuing education for instructors and health care personnel. The clinical component gives students the opportunity to provide hands on primary health care in Tivaouane. The research component includes the development of instruments to identify educational and health care needs. The fourth component includes educational activities relating to women's health.

Canada↗

[Evaluation of the efficacity of PESGUARD-PS 201 ultra low volume (ULV) spraying against mosquitos in the Pout area (Thies, Senegal)].

In September 1989, four weekly ULV applications of PESGUARD-PS (Pyrethroid) with SEMCO car mounted ULV aerosol generator in Pout (Thiès, Sénégal) were ineffective against adult populations of Anopheles arabiensis, Culex quinquefasciatus and others culicines. No decrease in the mosquito populations was observed both indoor and out door in the test area.

Animals↗

[Not Available].

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Demography↗