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Biomedical subjects

M Dodero

Publications and source records attributed to M Dodero.

At least 37 records · Page 2Linked to original sources

Chronic active hepatitis and mesopic vision in aged and non aged patients.

The time of macular functional-recuperation after dazzling has been evaluated in 46 patients of both sexes with ages between 26 and 65, with chronic active hepatitis (CAH). Knowing that the macular recuperation time, even under physiological conditions, increases after the age of 40, we divided these subjects in two groups: under 40 years old (20 cases) and over 40 years old (26 cases). Patients with CAH show a noticeably increased frequency of pathological times especially in those over 40 years old. In this group the pathological cases are 96,15% compared to 60% found among those under 40. The reason for this behavior is only hypothetic. However, the importance of the results must be underlined, as during biological and clinical remission of chronic liver disease patients of working age hold jobs where weakness of mesopic vision could cause serious accidents of legal-medical interest.

Accident Prevention↗

Toxic and immunodepressive effects of L-asparaginase from E. coli and from Erwinia carotovora following chronic administration in rats.

The effects of the administration of L-asparaginase from E. coli and Erwinia carotovora were studied in rats treated for 90 days with 800 or 3200 IU/kg body weight. The studies included overall toxicity on the liver, pancreas, and enteric mucosa as evaluated by both opitcal and electron microscopic examination, biochemical findings, behaviour of IgM-hemolysin producing cells, and antias-paraginase antibody production. The toxic effect and the immunodepressive activity appeared rather early, tending later to decrease. No sex correlation or clear cut dose correlation were observed. However, slight differences in toxicity between the two types of L-ASN-ase were present.

Animals↗

[Esophageal ulcer caused by Geotrichum candidum in a case of AIDS].

Isolate esophageal ulcer caused by Geotrichum candidum in a case of AIDS. We report the case of a 29-year-old white man, AIDS affected, presented with odynophagia, dysphagia and chest pain. X-ray and endoscopic study revealed an isolated esophageal ulcer whose culture demonstrated to be caused by Geotrichum candidum. This etiologic agent was not previously described in this kind of lesion.

Acquired Immunodeficiency Syndrome↗