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Biomedical subjects

M Dokić

Publications and source records attributed to M Dokić.

At least 19 recordsLinked to original sources
PubMed2005

Diet and bladder cancer: a case-control study.

To investigate possible relationships between diet and risk for bladder cancer in Serbia, the hospital-based case-control study was carried out. This study included 130 newly diagnosed bladder cancer patients and the same number of controls matched by sex, age (%+/-%2 years) and type of residence (rural or urban). Dietary information was obtained by using a food frequency questionnaire. Initial case-control comparisons were based on tertiles of average daily intake of control group. The odds ratios (ORs) were computed for each tertile, with the lowest tertile defined as the referent category. All variables (food items) significantly related to bladder cancer were included in multivariable logistic regression analysis. According to this analysis, risk factors for bladder cancer appeared to be consumption of liver (OR=6.60, 95%CI=1.89-23.03), eggs (OR=3.12, 95%CI=1.10-8.80), pork (OR=2.99, 95%CI=1.16-7.72), and pickled vegetable (OR=3.25, 95%CI=1.36-7.71). A protective effect was found for dietary intake of kale (OR=0.21, 95%CI=0.06-0.73), cereals (OR=0.19, 95%CI=0.06-0.62), tangerines (OR=0.21, 95%CI=0.07-0.68), cabbage (OR=0.27, 95% CI=0.11-0.68), and carrots (OR=0.15, 95%CI=0.05-0.41). The study indicated a potentially important role for dietary fat and pickled vegetables in bladder carcinogenesis. An inverse association was recorded between consumption of fruits, vegetables and cereals, and the development of bladder cancer.

Case-Control Studies↗
PubMed2002

[Acute hemolytic transfusion reaction].

Alloogenous blood and/or corresponding haemoproduct transfusion is an efficient and relatively safe supportive treatment. Despite the fact that pre transfusion investigation of both patients and donors ensure high degree of safety of this type of treatment, occurrence of adverse haemotherapy effects is possible and often unpredictable. Acute haemolytic transfusion reaction occur as a consequence of immune conflict between red blood cell membrane agents and specific antibodies present in plasma. Since it is impossible to completely avoid the occurrence of transfusion reactions, wherein acute transfusion haemolytic reaction present a serious, possibly life threatening complication, it is an imperative to continue to improve the knowledge on pathogenesis mechanisms leading to complications associated with these reaction and to define the most efficient therapeutical modalities.

Acute Disease↗
PubMed1990

[Allogenic transplantation of bone marrow in hematologic diseases. Preparation and completion of transplantation at the Hematology Clinic in Novi Sad].

The paper deals with the results of clinical preparations for the application of allogenic bone marrow transplantation at the Clinic of Hematology in Novi Sad. The obligation of the definite treatment of patients below 45 years by allogenic and autologous bone marrow transplantation results from the acceptance of the Yugoslav protocols for acute leukaemia treatment. Thus immunogenotypical analyses, so far performed in patients with severe aplastic anaemia have been extended to patients with acute leukaemia as well and then to patients with chronic myelogenous leukaemia, high risk lymphocYtic lymphoma and myeloma multiplex with resistance to standard chemotherapy and their potential sibling donors. The bone marrow transplantation Unit has been set up, the team of specialists has been formed and educated and the protocol for allogenic transplantation with Busulfan and cyclophosphamide combination for pretransplant conditioning has been adopted. In research work concerning the field of bone marrow transplantation a particular emphasis has been put on the working out of a mathematical model for optimal timing of bone marrow transplantation in patients with acute myelogenous leukaemia.

Adult↗
PubMed1981

[Appearance of hepatitis B in a family environment].

The study comprised 20 families with total of 83 members of whom 45 with hepatitis B. The selection was made of families with at least two members diseased which was the most common case, the marital couples being in question. Of other families, three families had three members and one family four members with hepatitis B virus infection. The largest number had severe clinical picture (44%) and 13 (28%) chronic active hepatitis. Four patients with the most severe clinical picture of chronic active hepatitis, together with HBeantigens, had positive HBeantigen for more than two years since the onset of the disease. Importance of damaged skin and mucosa in spreading of hepatitis B infection in family environment has been pointed out.

Adolescent↗
PubMed1981

[Identification of antibodies and selection of blood for transfusion].

The authors present us the identification of different antibody specificities which been discovered in a woman-patient suffered from SLE. Applying the method of absorption and elution of antibodies, anti-c, anti-E, anti-Fya, anti-K and anti-S have been identified. The authors applied the method where the high percentage dextran was used in order to get blood for transfusion.

Blood Group Antigens↗
PubMed1981

[Experience in the preparation of leukocytes and thrombocytes for transfusion].

The authors convey their experience gained during the work with Haemonetics M-30 Separator. They had performed 80 separations in total. They had separated leukocytes and thrombocytes simultaneously for 67 times. Most of the donors (51) had been stimulated by corticosteroids in order to obtain the increase of yield. The average concentrate quantity was 355 +/- 91 ml. The leukocytes yield in the concentrate was means = 27,3 +/- 7,8 x 10(9)/1, with 19,2 +/- 5,6 x 10(9)/1 (70%) of polymorphonuclears. The thrombocytes yield was means = 7,80 +/- +/- 1,83 x 10(11)/1. Only thrombocytes were separated 13 times. The average concentrate quantity was 273 +/- 77 ml. The thrombocytes yield in the concentrate was 8,94 +/- 1,26 x 10(11)/1. During the study, the symptoms and signs of hypotony appeared in one the donors.

Adult↗
PubMedDate not supplied

[Epidemiologic characteristics of hemorrhagic fever with renal syndrome in a military population].

In the period 1952-1990 there have been recorded 84 patients with hemorrhagic fever with renal syndrome (HFRS): 81 soldiers and 3 officers of the Y.P.A. The largest number of cases was recorded in three epidemics, 61 or 72.6%. In 94% of cases the infection occurred during camping of units. The disease appeared in all months, but 57.2% of cases occurred in June and July. The mean lethality was 2.4%, in epidemics 1.6% and as sporadic cases 4.3%. In an army unit staying for six months in HFRS focus, 9.8% of soldiers were infected by the causative agent of this infection and only in one case the clinical picture of HFRS was manifested. Serologic tests (IIF and ELISA) confirmed the diagnosis of HFRS. Virus strains of Hantaan, Puumala and Seoul groups were used as antigens.

Disease Outbreaks↗
PubMedDate not supplied

Eight red cell enzymes polymorphisms in the Slovakian ethnic group of Yugoslavia.

The polymorphisms of eight red cell enzymes were studied in 211 unrelated voluntary blood donors from the ethnic group of Slovakians (Yugoslavia). Only common phenotypes were detected, which are usually present in European populations. The allele frequencies found were: GLO1*1 = 0.410, ESD*1 = 0.887, AK1*1 = 0.962, PGM1*1 = 0.780, ACP1*A = 0.315, ACP1*B = 0.637, ACP1*C = 0.047, GPT*1 = 0.535, ADA*1 = 0.952 and PGD*A = 0.940. These findings are discussed in the context of other European populations and the population of Serbia, Yugoslavia.

Alleles↗