Biomedical subjects
Publications and source records attributed to M Dombriz.
The authors report a case of a pelvic site of a Castleman pseudo-tumour, still called angio-follicular hyperplasia or lympho-vascular hamartoma. This disorder of unknown aetiology may be situated anywhere along the lymphatic chains (70% of cases in the mediastinum). It is often associated with immuno-haematological disorders. Suitable for surgical treatment, the course is always favourable.
The authors report on three new cases of tumours growing in bladder diverticula. If an intravenous urogram (IVU) of high quality is obtained and properly interpreted--in almost all cases a diverticular lacuna will be seen. Such an IVU picture is most suspicious in a patient with haematuria. The impossibility, for technical reasons, of exploring the interior of the diverticulum endoscopically means that the diagnosis cannot be ruled out. These tumours have a bad prognosis: 13% 3 year survival and 5% survival at 4 years. The authors reach the conclusion which is in agreement with the literature, that these tumours need to be treated radically.
The authors, after personally observing three cases, review the literature on breast cancers in patients with prostatic cancer treated by estrogens. The authors' three cases are all metastatic breast cancers, and one has also a renal cancer. These three cases are added to the 22 reported in the literature which include 13 metastatic cancers, 6 primary breast cancers, and 3 cancers of unspecified nature. The seriousness of these breast involvements is obvious when they are a manifestation of tumor dissemination. The authors discuss the possible responsibility of the estrogen therapy in the development of the breast cancer. The downhill course and the appearance of breast cancer with generalized dissemination evinces an important decrease in the patient's immunity which allows metastases and multiple tumors to occur.
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On the basis of a case of thoracic ectopic kidney, discovered following trauma and diagnosed at laparotomy (since it was confused with rupture of the left diaphragm) the authors review certain data concerning this rare malformation (150 published cases). --The site of origin of the renal artery may be used to distinguish on the one hand between true intra renal ectopic kidney with the renal artery arising from the aorta and secondly trans-diaphragmatic herniation of a kidney with a kidney with a normal vascular pedicle through a hernia, most often congenital, and equally often right as left. --Clinically, at the time of a routine examination or following trauma, chest X-ray reveals an opacity at the base of the thorax, the low and posterior topography of which is suggestive of the diagnosis and and IVP is then indicated. In the absence of violent trauma, the diagnosis of traumatic hernia is eliminated. The distinction between true ectopic kidney and congenital trans-diaphragmatic hernia becomes a false problem since there is no need for treatment in either case.