PubMed Health⌕ Search

Biomedical subjects

M Driessens

Publications and source records attributed to M Driessens.

31 records · Page 2Linked to original sources
PubMedDate not supplied

A retrospective study of the conservative treatment of tennis-elbow.

The files of 64 patients (70 tennis elbows) treated in our department because of tennis elbow complaints, were reviewed. The results showed injection with a corticosteroid preparation to be effective in alleviating the pain in the short term (91% improvement within 1 week), but the incidence of recurrence of symptoms to be high (51%) after an average period of 3 months). Physical therapy appeared to be less effective (47% improvement after an average of 6 weeks or 20 sessions), but recurrence of symptoms was far less frequent (5%).

Adrenal Cortex Hormones↗
PubMedDate not supplied

[Correlation between motor terminal latency time of the median nerve and the result of conservative treatment (cortisone injection) in carpal tunnel syndrome].

45 patients with carpal tunnel syndrome could be followed after an initial conservative treatment (local injection with Depomedrol 40 mg) either up to a surgical intervention (15 patients) or up to 14 to 48 months after the first injection (mean 23 months). Pregnant patients were excluded, as well as the patients with a distal motor latency (DML) greater than or equal to 7 msec (immediate surgical intervention). The age and sex distribution corresponds with the data reported in the literature: 7 males (15%) versus 38 females (85%), including 7 between 20 and 39 years (16%), 24 between 40 en 59 years (53%) and 14 between 60 and 80 years (31%). The side of the complaints also corresponds with the literature data: bilateral 16 (36%), right hand 23 (51%), left hand 6 (13%). In the 16 patients with a DML greater than 5,5 msec (normal value up to 4.3 msec) a rapid recurrence of the complaints after the injections necessitated a surgical intervention in 12 cases. In the 29 patients with a DML less than or equal to 5.5 msec who had been operated, the improvement of the complaints after the first injection lasted 2 months at most in 8 cases, as opposed to an average of 12.5 months (0 to 48 months) for the population as a whole.

Adult↗
PubMedDate not supplied

[Mesotherapy in abarticular rheumatism].

Mesotherapy is a method of treatment in which subcutaneous infiltrations are given loco dolenti at short intervals of time. In this way a mixture of readily available drugs is administered. There are many indications for mesotherapy, although most applications are found in the field of the osteo-articular affections. As yet there is no scientific explanation for the effect of this therapy. Studies on this subject are currently being performed.

Humans↗
PubMedDate not supplied

F-wave latencies of the deep peroneal nerve in diabetic polyneuropathy.

The F-wave latency of the deep peroneal nerve in function of leg length was determined in 66 normal persons and 25 diabetic patients with known polyneuropathy. The latencies were measured by stimulating the nerve at the ankle and recording the F-wave at the musculus extensor digitorum brevis using a needle electrode. The leg length was represented by the distance between the spina iliaca anterior superior and the lateral malleolus. The F-wave latencies obtained in diabetic patients were significantly higher than in controls (p less than 0.01). The method is suitable to detect polyneuropathy, especially in early cases where the conventional techniques (determination of the motor and/or sensory latencies and/or conduction velocities at the lower limbs) may still yield normal or borderline values. The upper limits of the normal values of the F-wave latencies in function of leg length is given by a non-linear curve, which can be represented by the equation: F-wave latency (msec) = 14.7 + 47.5 x (leg length in m)2. For practical purposes, the upper limit of the normal value for a given leg length can be readily determined from a latency-length curve.

Adult↗
PubMedDate not supplied

The role of integrins and integrin activation in liver metastasis.

An overview is presented of our studies on the interaction between blood-borne tumor cells and the tissues where metastases are formed, in particular the liver. Using blocking antibodies and tumor cell mutants, we have identified the adhesion molecules involved, which so far are all integrins. Strikingly, tumor cell lines that are quite similar, and invade in a comparable fashion, use distinct integrins. Lymphomas that invade the liver massively and diffusely use LFA-1 or fibronectin receptors to adhere to hepatocytes. We have obtained evidence that LFA-1 is activated during the interaction by factors that act through G-protein-coupled receptors, and preliminary results suggest that the same may be true for the fibronectin receptors. Whereas TA3/Ha murine mammary carcinoma cells adhere to hepatocytes via alpha 6 beta 4, TA3/St variant cells of the same tumor bind via the fibronectin receptor alpha 5 beta 1. Adhesion of the TA3/Ha cells appears to be impaired by the mucin epiglycanin that is abundantly present on the surface of these cells.

Animals↗
PubMedDate not supplied

Cryptotetany--place of EMG-recording.

Ninety-two cryptotetany tests were performed with simultaneous EMG-recording in the M. Interosseus dorsalis I and the M. Opponens pollicis. It was found that, in 21 cases out of 92 (22.8%), exclusively in the M. Interosseus dorsalis I, and in 11 cases out of 92 (11.9%), exclusively in the M. Opponens pollicis, multiplet activity was detected for at least 2 minutes. From this study it appears that, in performing the cryptotetany test, the M. Opponens pollicis is certainly not be preferred to the M. Interosseus dorsalis as the only place of recording. It appears, on the contrary, that simultaneous recording in the M. Interosseus dorsalis I and the M. Opponens pollicis is to be preferred to a recording exclusively in the M. Interosseus dorsalis I. In this way, a not unsignificant number of false negative cryptotetany tests can be avoided.

Adolescent↗