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Biomedical subjects

M Drucker

Publications and source records attributed to M Drucker.

At least 55 records · Page 3Linked to original sources
PubMed1989

Clinical and laboratory findings of spotted fever in Israeli children.

In a prospective study of 70 Israeli children with spotted fever the major clinical features were fever (100%), skin rash (98.5%), myalgia (54%) and vomiting (40%). Thrombocytopenia (75%) and hyponatremia (62.5%) were common, but were not associated with increased mortality. Antibodies to Rickettsia conorii were detected by the indirect immunofluorescent antibody assay. In one patient Rickettsia was grown from blood. Contacts with dogs were reported in 17 of 40 patients questioned, and in only 2 was a canine tick bite obvious. Hospitalization was required in 11 (16%) patients. There was 1 fatality. The rickettsia responsible for spotted fever in Israel appears to be an antigenic variant of R. conorii. Early recognition and treatment of this disease permits rapid eradication of the rickettsiae and facilitates complete recovery.

Antibodies, Bacterial↗
PubMed1987

Shigella bacteremia in adults. A report of five cases and review of the literature.

Shigella bacteremia is rare, occurring mainly in children. We describe five adult patients with Shigella bacteremia and review data on 22 cases reported in the English-language medical literature. Eighteen (67%) of 27 patients had either an underlying condition or were aged older than 65 years. Most patients had clinical signs of acute febrile gastroenteritis. However, in six patients, the organism was not isolated from stool. Species isolated from blood included Shigella flexneri in 11 patients, Shigella sonnei in eight, and Shigella boydii and Shigella dysenteriae in one patient each. Isolation of the bacterium from blood only was associated with a high mortality rate, in contrast to its isolation both from blood and stool. It is suggested that blood cultures should be obtained from elderly or immunocompromised patients with acute febrile gastroenteritis to detect shigellemia as well as bacteremia caused by other enteric pathogens, such as Salmonella or Campylobacter.

Adult↗
PubMed1983

A mental health consultation program to the police.

The growing interface between psychiatric staff and the police as a result of the latter's involvement with disturbed patients released into various communities has intensified the need for appropriate police orientation and desensitization to these patients. This article describes a program that grew out of the need of the police for involvement with psychiatric staff, once their resistance had been overcome. The use of videotapes and role playing diminished the anxiety of the police, allowed their better and more rational judgments to come forth when faced with such patients, and increased their empathy. Another goal of the program was to get the police to see that a more reflective and restrained approach to patients, as distinguished from an aggressive, action-oriented approach, was just as demanding of their professionalism and could be more effective and safer in the management of these patients.

Community Mental Health Services↗
PubMed1983

Urinary tract infection and drug-resistant bacteria in different patient populations.

A 1-year survey of the pathogens causing urinary tract infections was conducted in three institutions: a rehabilitation hospital, a general hospital and outpatient clinics. Gram-negative rods accounted for 96% of the infections. In the general hospital and the outpatient clinics, Escherichia coli was the most prevalent pathogen, while Proteus sp. were most prevalent in the rehabilitation hospital. The frequency of drug-resistant isolates was significantly higher in the rehabilitation hospital than in the general hospital and the outpatient clinics. This was most conspicuous in the use of the beta-lactam antibiotics, aminoglycosides and sulfonamides against such organisms as E. coli, Klebsiella sp., Enterobacter sp. and Proteus sp. Urinary E. coli were more sensitive to antimicrobial drugs than were other urinary pathogens. Pseudomonas aeruginosa isolates were highly resistant to most antibiotics. About half of the isolates were resistant to gentamicin and another half to carbenicillin. In some instances the frequency of drug-resistant isolates was higher in the general hospital than in the outpatient clinics, reflecting the greater usage of antimicrobials in the general hospital.

Anti-Bacterial Agents↗
PubMed1983

Replacement of gentamicin by amikacin as a means of decreasing gentamicin resistance of gram-negative rods in a neonatal intensive care unit.

The emergence of resistance in bacteria that colonize infants in a neonatal intensive care unit (NICU) is of great concern and a serious therapeutic problem. During the years 1980 to 1981, continuous surveillance of bacterial colonization was carried out on 499 infants admitted to the NICU of the Beilinson Medical Center. Antibiotic sensitivity testing was performed on all organisms isolated. At the end of 1980 and the beginning of 1981, an increased number of gram-negative rods became gentamicin-resistant. It was assumed that the discontinuation of gentamicin usage and replacement with another aminoglycoside, amikacin, would bring about a reduction in gentamicin resistance. Replacement of gentamicin by amikacin resulted in a significant decrease in gentamicin-resistant Escherichia coli and Klebsiella within 3 to 6 months. The emergence of resistant strains can be detected by surveillance methods and overcome by a change in the antibiotic regimen.

Amikacin↗
PubMed1980

Microorganisms isolated from blood and cerebrospinal fluid in a general hospital. Clinical implications.

This study is a review of 1,040 significant positive blood cultures from 415 patients, and 44 positive cerebrospinal fluid cultures from 44 patients treated at the Meir General Hospital during the period 1976-78. The most frequent isolates from blood cultures were Escherichia coli, Staphylococcus aureus and Klebsiella pneumoniae. The most frequent isolates from cerebrospinal fluid cultures were Streptococcus pneumoniae, Haemophilus influenzae and Neisseria meningitidis, which were present in similar proportions. E. coli was predominant in the division of medicine, Staph. aureus in the division of pediatrics and Klebsiella in the division of surgery. Fifty percent of the E. coli isolates were sensitive to ampicillin and carbenicillin; about 80%, to cephalothin and sulfamethoxazole-trimethoprim; and 100%, to gentamicin. Only 7% of the Klebsiella isolates were sensitive to apicillin; 72% were sensitive to cephalothin and 87%, to gentamicin. Only 18% of Staph. aureus isolates were sensitive to penicillin, but about 95% were sensitive to methicillin or cephalothin. Two of 10 salmonellae isolates and 13% of H. influenzae were resistant to ampicillin.

Blood↗
PubMed1976

[Celiac disease].

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Celiac Disease↗