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Biomedical subjects

M Duboisset

Publications and source records attributed to M Duboisset.

At least 19 recordsLinked to original sources
PubMed1988

[Value of the continuous Doppler in the evaluation of gradients of aortic valvular stenosis in the adult].

The purpose of this study, performed in 80 patients with aortic valve stenosis, was to find out whether continuous wave doppler ultrasound was reliable in assessing the severity of the stenosis. Maximum mean and instantaneous transaortic pressure gradients obtained by continuous wave doppler were compared with maximum mean instantaneous and peak to peak gradients simultaneously obtained by cardiac catheterization. 35 patients who underwent aortic valve dilation were explored beforehand and afterwards, which brings up to 115 the total number of gradient comparisons. There was a correlation between maximum instantaneous gradient at doppler and peak to peak gradient (r = 0.62, n = 115, e = 22.5 mmHg, p less than 0.001). A similar correlation was found between maximum instantaneous gradients at doppler and haemodynamics (r = 0.64, n = 80, e = 24.5 mmHg), but correlation between mean gradients was weaker (r = 0.57, n = 80, e = 17.7 mmHg). Maximum and mean instantaneous gradients are underestimated by the doppler method. After exclusion of imperfect doppler curves, correlations were better, notably as regards mean gradients (r = 0.80, n = 18, e = 11.9 mmHg). There was a closer correlation between doppler maximum instantaneous gradients and haemodynamic peak to peak gradients in patients without aortic regurgitation (r = 0.71, n = 45, e = 17.2 mmHg) than in patients with aortic regurgitation (r = 0.54, n = 70, e = 24.3 mmHg).(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1978

[Comparison of echocardiography and phonomecanography in adult aortic valve stenosis. 55 cases].

The results of echocardiography and phonomecanography were compared in 55 cases of adult valvular aortic stenosis. Although the most reliable echocardiographic sign of the severity of stenosis is the systolic separation of the aortic valve echos, it should be amphasised that: -- this cannot be measured in 25 % cases; --in 10 % cases the values obtained vary with the angle of the transducer. In these cases, the finding of a left ventricular posterior wall thickness greater than or equal to 15 mm is specific for severe aortic stenosis. On the other hand, the left atrial, left ventricular and aortic internal dimensions and the morphology of the mitral leaflets do not help in the estimation of the severity of adult aortic stenosis. The best correlations between echo and phonocardiography are the values of aortic valve opening and : --hemi-ascension time (r = 0.67); --left ventricular ejectiontime (r = 0.93) when patients in cardiac failure are excluded. The complementary nature of these two investigations is notable, and should, in pure aortic stenosis without angina, spare patients who are often elderly and fragile from heamodynamic investigation.

Aged↗
PubMed1975

[Value of hemodynamic exploration under exercise in chronic bronchitis].

Pulmonary haemodynamics was studied in the course of a calibrated exercise test on an ergometric cycle in 55 patients with chronic obstructive respiratory disease. Three groups of patients could be distinguished: absent pulmonary artery hypertension, both at rest and on exercise (group I), pulmonary artery hypertension on effort only (group II), permanent pulmonary hypertension, both on effort and at rest (group III). If adaptation of the cardiac output to exercise was identical in three groups and appeared to be normal, the relationship between pulmonary artery pressure and flow differed clearly from one group to another. Elements of orientation make it possible to foresee this latent pulmonary artery hypertension on the basis of rest gazometry and simple spirography data. The prognostic and aetiologic significations were discussed.

Bronchitis↗
PubMed1975

[Effects of post-infarct physical training on physical fitness and cardio-circulatory adaptation to effort].

In fifteen patients recovering from a myocardial infarction dating of at least three months, examined at rest or during a submaximal exercise, various circulatory (cardiac rate, blood pressure, cardiac output...) and ventricular parameters (oxygen consumption, ventilation per minute) both before and after a program of physical training for a period of six to eight weeks. The benefit of readaptation was judged on the increased work capacity (VO2max increase of 24.6%) and the improvement of cardio-circulatory adaptation during a submaximal exercise: reduction of the cardiac rate by 11%, of Katz's index by 12.6%, of the cardiac output by 5.8% and of the left ventricular work by 8.8%. This cardiac thrift at the origin of the increase of physical aptitude is essentially due to a better peripheral circulation adaptation to exercise, as indicated by the increased oxygen arterio-ventout difference by 11.4%.

Adult↗
PubMed1975

[Value of the exercise test in the functional evaluation of non-coronary cardiac patients].

72 cardiac patients underwent an exercise test on the bicycle ergometer, with direct measurement of the oxygen consumption (VO2). These results are compared with those of 55 healthy subjects undergoing the same test. The amount of handicap varied with the nature of the cardiac lesion, being 39% for the mitral and cardiomyopathy groups, 31% for those with both mitral and aortic valve disease, 27% for the aortic valve group, and 25% for those with congenital abnormalities. The linear relationship between Watts and VO2 was reproduced both in the healthy and cardiac subjects, which allows us to calculate the value of VO2 under conditions of load for more than 3 minutes during a standardized exercise test.

Adult↗