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Biomedical subjects

M Dupree

Publications and source records attributed to M Dupree.

7 recordsLinked to original sources

Opportunity on the edge of orthodoxy: medically qualified hydropathists in the era of reform, 1840-60.

Following the lead of the Lancet's attacks in the 1840s, historians have considered hydropathy and hydropathists in Britain as part of fringe or heterodox medicine. Yet the distance between varieties of orthodox theory and practice and hydropathy was small, and many of the most prominent hydropathists held orthodox views and qualifications. Examining the educational backgrounds and careers of 40 early British hydropathists, the authors suggest that hydropathy and hydropathic establishments, like specialists hospitals, asylums, and spa practice, provided an alternative niche to general practice in the crowded British medical market and a way to 'fame and fortune' for medical men outside the metropolitan élite.

Complementary Therapies↗

Delay in diagnosis: indeterminate leprosy presenting with rheumatic manifestations.

BACKGROUND: Rheumatic complications are common in leprosy (Hansen's disease) and can be the primary complaint delaying accurate diagnosis. OBJECTIVE: Such a case is reported here: a 61-year-old woman with indeterminate leprosy presented with symmetric arthritis and purpura. Despite biopsy and evaluation by several physicians, leprosy was not suspected. After 2 years of progressive symptoms, a second biopsy revealed lepromatous leprosy. CONCLUSION: In this case, lack of clinical suspicion and unfamiliarity with the histology of indeterminate leprosy delayed diagnosis and treatment. Leprosy should be considered in the differential diagnosis of patients presenting with unusual rheumatic and persistent cutaneous manifestations.

Arthritis↗

Acquired vulvar lymphangioma mimicking genital warts. A case report and review of the literature.

A 44-year-old female developed confluent, dusky red, pruritic labial papules clinically suspected to be genital warts. She had a long-standing history of Crohn's disease with vulvar fistulae. The papular eruption developed after several bouts of cellulitis in a region of vulvar lymphedema. Shave biopsy of a papule exhibited papillated epidermal hyperplasia overlying a dermis with a 'Swiss-cheese' appearance secondary to lymphedema and superficial ectatic thin-walled vascular spaces characteristic of lymphangiectasias. Review of published cases reveals that acquired lymphangiomas often affect the vulva compared to other cutaneous sites and can be associated with surgery, radiation therapy, infection (e.g., erysipelas, tuberculosis), Crohn's disease, congenital dysplastic angiopathy and congenital lymphedema. Rather than translucent vesicles ('frog spawn') typical of extragenital cutaneous lymphangiomas, vulvar lymphangiomas often present as verrucous papules that can be mistaken for genital warts. In this case, we believe that the combination of vulvar Crohn's disease and recurrent cellulitis resulted in local lymphatic destruction, lymphedema and ultimately symptomatic lymphangiectasias that mimicked genital warts.

Adult↗

Hemangiomas in infants and children. An algorithm for intervention.

Considerable confusion exists with the diagnosis and management of vascular birthmarks. For this article we reviewed charts for the diagnosis and recommended management of 208 new patients with vascular birthmarks presenting to the Albany Medical Center Vascular Malformation Clinic, Albany, NY, over a 26-month period from October 1995 through December 1997. Based on our patient population, data available, and the current literature, we concluded that an early evaluation and an accurate diagnosis in infants with a vascular birthmark are important. Furthermore, intervention by way of systemic steroids, laser therapy, or surgical debulking is appropriate and safe in a select group of patients presenting with a proliferating hemangioma and in patients with an involuting but disfiguring hemangioma. Also in this article we present an algorithm to assist the clinician with the management of the pediatric patient with a diagnosis of a hemangioma.

Adrenal Cortex Hormones↗