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Biomedical subjects

M Durán

Publications and source records attributed to M Durán.

35 records · Page 2Linked to original sources

[Study of diastolic regurgitation of the atrioventricular valves using Doppler echocardiography].

In order to evaluate diastolic regurgitant flows in atrioventricular valves, we studied by Doppler echocardiography four patients in whom electric abnormalities like third degree atrioventricular block, pacemaker dysfunction and ventricular arrhythmias with atrioventricular dissociation were detected. In all of them, mitral and tricuspid high velocity regurgitant flows were found in systole. A second regurgitant atrioventricular flow was also registered, this flow being diastolic, intermittent, and with a lower velocity profile than the systolic regurgitation. The hemodynamic importance of this diastolic regurgitant flow over the cardiac output has not been well defined; in our cases the ventricular filling was not substantially modified by diastolic regurgitant flow.

Aged↗

Luteal phase evaluation after clomiphene-chorionic gonadotrophin-induced ovulation.

Fifty infertile patients treated with clomiphene and hCG for induction of ovulation were studied with plasma progesterone measurement and endometrial histology. Five patients (10%) presented defective endometria and low plasma progesterone in spite of biphasic BBT charts with normal luteal phase length. Forty-five patients (90%) had significantly higher plasma progesterone concentrations than those found in a control group of fertile women, but a defective endometrial secretory pattern occurred in 19 of these 45 patients (42.3%). These data suggest the need for monitoring the response to clomiphene by endometrial histology in addition to BBT and plasma progesterone, or for supplemental therapy to overcome the endometrial luteal phase deficiency in clomiphene-treated cycles.

Adult↗

[Primary sclerosing cholangitis associated with ulcerative colitis].

The authors report a patient with a primary sclerosing cholangitis associated with ulcerative colitis. There are comments on the histopathology and evolution of the illness. The patient has recovered from the chronic inflammatory bowel disease in a satisfactory way, however it seems that the primary sclerosing cholangitis it way apart from the colopaty.

Cholangiopancreatography, Endoscopic Retrograde↗

Microsurgical extrahepatic cholestasis in the rat: a long-term study.

An experimental model of microsurgical cholestasis is studied as an alternative to the most frequently used surgical techniques, based on the section of the common bile duct. This microsurgical technique consists of the resection of the extrahepatic biliary tract, that is, of the common bile duct in continuity with the bile ducts that drain the four lobes of the rat liver. At 30 days of evolution, rats with microsurgical cholestasis do not develop biliary pseudocysts or intraperitoneal hilar hepatopulmonary abscesses and show an increase (p < 0.001) in total bilirubin (9.50 +/- 1.50 mg/dL vs. 1.60 +/- 0.35 mg/dL), bile acids (225 +/- 87 micromol/L vs. 12.5 +/- 14.50 micromol/L), gamma-glutamyltranspeptidase (375 +/- 143 U/L vs. 8 +/- 11 U/L), and alkaline phosphatase (73 +/- 25 U/L vs. 23 +/- 4 U/L) levels. The histological study shows fibrosis with biliary proliferation. The microsurgical cholestasis technique is a valid alternative to other techniques and can be an adequate experimental model for the study of etiopathogenic mechanisms of obstructive jaundice and especially to study extrahepatic biliary atresia.

Animals↗