PubMed Health⌕ Search

Biomedical subjects

M Durigon

Publications and source records attributed to M Durigon.

At least 55 records · Page 3Linked to original sources

Age estimation from quantitation of features of "chest plate" X-rays.

This study presents a method for estimating the age at death from the quantitation of roentgenologic features of X-ray films of chest plates obtained during routine autopsies. Multiple linear regression analysis allows estimation of coefficients of regression of features on known age-at-death individuals. The regression equation can be used in turn for age estimation of an unknown age-at-death individual. The accuracy of age estimation is about +/- 8.4 years (standard error) which is in the range of previously published macroscopic methods, though the present method is much faster and simpler.

Adolescent↗

Postmortem interval estimation by biochemical determination in birds muscle.

Experimental postmortem interval estimation was assayed by various biochemical components of hens pectoral muscle. Among them, only percentage of non-protein nitrogen on total soluble protein, asparatic amino transferase activity and creatinine concentration showed significant correlation with time after death. Asparatic amino transferase was negatively correlated and non-protein nitrogen percentage and creatinine were positively correlated to postmortem interval. The stronger correlation (0.925) was found for creatinine.

Animals↗

Histological assessment of gestational age in human embryos and fetuses.

A light microscopic study performed on 760 human fetuses allows us to define several stages in their visceral development and to relate these to gestational age. The histological examination of most viscera, such as the central nervous system, is useless when the tissue preservation is poor. Nevertheless, three organs may still be studied in macerated fetuses: the lungs (where different glandular, canalar, and alveolar stages of development are evident), the kidneys (where the respective numbers of rows of primitive glomeruli and of generations of mature glomeruli vary after week 22), and the adrenal glands (where neuroblastic nests are normally found between weeks 7 and 26 of gestation). It is important to compare the degree of histological maturation with the clinical, macroscopic, and radiologic data in order to define the profile of maturation proper to each human fetus.

Adrenal Glands↗

[Anatomo-pathological study of enthesopathies in inflammatory spondylarthropathies].

The authors report the pathological aspects observed in three peripheral entheses (spine of the scapula, talus and patella) of inflammatory spondylo-arthropathy (ISP). A mononuclear inflammatory infiltrate, more or less important, is found in all cases corroborating the rare findings in the literature. Until now, the anatomical study of ISPs was uneasy because of the difficult approach of the sacro-iliac joint and the spine due to their anatomical location. The present study, in spite of the small number of reported cases, proposes to show that inflammatory lesions may be studied in peripheral entheses which are more accessible to biopsies, and suggest the development, in the future, of a more minutious study of the different varieties of ISP.

Adult↗

Experimental bone marrow alterations following single and multiple high-dose steroids in rabbits.

Nineteen New Zealand white rabbits received one (n = 5), two (n = 5), or three (n = 9) injections of 60 mg methylprednisolone and were sacrificed 10, 20, 30, and 60 days following the last treatment. They were compared to 15 controls for histological examination of femoral and humeral epiphyses and femoral condyles. Treated animals had a significant rise in serum triglycerides (p less than 0.01) 10 days following treatment. 15 treated animals and 6 controls had grade I lesions of bone marrow (p less than 0.05). Lesions of grades II and III were only observed in 5 treated animals. The severity of histological lesions were not correlated with steroid doses. Tetracycline fixation was suppressed in treated rabbits.

Animals↗

[Medicolegal identification by the dental system].

Bodies found in acts of war or natural disasters are sometimes impossible to identify for police or legal purposes, notably because of calcination or putrefaction. Teeth, which are particularly resistant to destruction by fire, bacteria or other agents, can be used to evaluate the victim's dental age by the Gustafson method with a margin of error of plus or minus 4,6 years. Blood group has also been established with more than 85% concordant results by determination of the A. B. O antigens which are present in dental tissue and pulp. These techniques were tested on 257 teeth from subjects of known dental age and blood group. They provide additional evidence of the identity of deceased persons.

Accidents, Aviation↗

[Histological morphometric methods. II. Automatic analysers (author's transl)].

Histological morphometric methods can be divided into three groups depending on their automation degree: manual methods, semi-automatic methods, fully automatic methods. Among fully automated image analysers, one can separate devices into three main subgroups: 1 - general purpose systems controlled by software can be programmed to undertake an infinite variety of tasks. 2 - general purpose systems with limited repertoire of analysis, controlled by hardware programs. 3 - simple task instruments controlled by hardware programs (e.g. Hematrak, Leitz). Whichever instrument is used, three steps take place in an automated image analysis procedure: 1 - image numeration. 2 - parameters extraction. 3 - parameters interpretation. The NS 2000 image analyser belonged to the 2nd subgroup of the above mentioned systems. Its built-in hardware algorithm works just like successive erosions on images. An example (breast carcinoma tissue section) is given in order to illustrate performances of this peculiar image analyser.

Automation↗

[Histological morphometric methods. I. Semi-automatic methods on graphic tables (author's transl)].

Two kinds of parameters are accessible by histological morphometric methods: --actual quantitative ones (e.g. length, area) --discontinuous ones (e.g. cells, nucleus or mitochondrium counting). Measures were all achieved by manual methods in past. Nowadays, apparatus are existing that can solve semi-automatically histomorphometric problems. These apparatus are variously named digitizer, digitizing table, digitalizing table, graphic table and so on. Two histomorphometric examples are described one concerning breast carcinoma the other myocardial vascularization in rats. They both have been treated on a graphic table. Problems and their solutions are developed.

Animals↗