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Biomedical subjects

M E Bronshteĭn

Publications and source records attributed to M E Bronshteĭn.

At least 19 recordsLinked to original sources
PubMed1989

[Crisis of arterial hypertension in patients with primary aldosteronism].

A clinical picture of the disease was analyzed in 55 patients with primary aldosteronism due to adrenal aldosteronoma. A crisis variant of the course in arterial hypertension was detected in 50% of the patients. Its comparison with morphological signs of the adrenals enabled the authors to reveal that the crisis of arterial hypertension was accompanied by adrenal medullary hyperplasia and hyperfunction.

Adrenal Cortex Neoplasms↗
PubMed1988

[Catecholamine-producing tumors of the chromaffin tissue. Morphological and ultrastructural characteristics].

Histological and ultrastructural studies were carried out in 41 hypertensive patients showing increased urine excretion of catecholamines and vanilmandelic acid due to chromaffinoma of the adrenal and other sites: malignant chromaffinoma of the adrenal, including multiple--55%, border-line chromaffinoma--34% and malignant--11% (total--53 tumors). Ultrastructurally, malignant chromaffinoma showed pronounced aniso- and poikilocytosis, lack of desmosomes, presence of dark and clear cells, irregular and bizarre-shaped nuclei and enlarged nucleoli. An inverse correlation between the level of secretory granules and that of organelles was established for all sites and patterns of growth. The data obtained suggest certain ultrastructural peculiarities which alongside with macro- and microscopic features serve identification of malignity of tumor, functional status of tumor cells and type of secretion.

Adolescent↗
PubMed1987

[Clinical and morphologic characteristics of low-renin hyperaldosteronism].

A comparative assessment of the results of differential-diagnosis load tests and morphologic changes in adrenal tissue removed at surgery has been carried out in patients with arterial hypertension and low-renin hyperaldosteronism. Assessment of plasma aldosterone variations in response to load tests has shown this parameter to be unrelated to the structure of aldosteroma, either before or after the test. Different patterns of aldosterone production control were demonstrated in cases of diffuse-nodular and adenomatous adrenal changes. The study has provided additional information on the pathogenesis of this condition.

Adrenal Cortex↗
PubMed1980

[Surgical treatment of different forms of hyperaldosteronism with low renin activity in the blood plasma].

The clinical picture and biochemical values in patients with arterial hypertension and concomitant hyperaldosteronism and low renin activity in blood plasma due to adenoma of the adrenocortical glomerular zone and in its absence were studied before and after surgical treatment. An attempt is made to substantiate the expediency of surgical or nonoperative treatment of patients with aldosteroma or bilateral hyperplastic process in the adrenals.

Adrenal Cortex Neoplasms↗
PubMedDate not supplied

[Morphology of the ovaries in congenital virilization of the external genitalia in persons with genetic and gonadal female sex].

A study was made of the resected ovarian tissue in 7 patients with congenital virilization of the external genitalia (CVEG). In patients with CVEG there occurred not very pronounced changes in the ovaries seen in diencephalic syndromes with the involvement of the ovaries into the pathological process (hypertrophy of the theca interna cells of the cystically changed follicles, hyperplasia of the intestinal tissue of the cortical layer with the transformation of individual cells into epithelioid, etc.). There were clinical signs indicating an acceleration of maturation of the diencephalic structures (some tendency to the acceleration of sexual development, and distinct signs of diencephalic pathology on the EEG). A conclusion was drawn that in the patients with CVEG the ovaries do not serve as the source of andronization of the organism. It is supposed that in these patients the source of hyperandronization existed at the period of formation of the external genitalia of the fetus and that the adrenal cortex of the fetus could serve as this source.

Adolescent↗
PubMedDate not supplied

[Morphological variants of thyroid autoimmune diseases].

Analysis of the structural features of thyroid tissue, removed from 250 patients with Graves' disease, made it possible to define 3 morphological variants of Graves' disease differing not only by the type of pathological changes in the thyroid but also etiopathogenetically. One of the variants (parenchymatous type of the thyroid structure) may be of nonautoimmune origin; the second one is of primary autoimmune genesis (the classical variant, Basedow's disease, toxic goiter), and the third one is colloidal proliferating goiter with the autoimmune component (in approximately 50% of cases). Analysis of the structural features of thyroid tissue of 250 patients with Hashimoto's disease made it also possible to define its 3 morphological variants, differing both in a degree of expression of thyroid lymphoid infiltration and in the type of parenchymatous and stromal changes.

Adolescent↗