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Biomedical subjects

M E Faulstich

Publications and source records attributed to M E Faulstich.

At least 19 recordsLinked to original sources

Assessment of anxiety in adolescents: concurrent and factorial validities of the Trait Anxiety scale of Spielberger's State-Trait Anxiety Inventory for Children.

The purpose of this study was to evaluate the concurrent and factorial validities of the Trait Anxiety scale of Spielberger's State-Trait Anxiety Inventory for Children when given to 157 adolescents. Using a randomly selected subsample of 88, correlations between total and factor scores on the children's inventory and on the Revised Children's Manifest Anxiety Scale were statistically significant but lower than those reported previously for children. Principal component analyses of these adolescents' scores on the Trait Anxiety scale of the children's inventory replicated previous factor analytic studies of this inventory administered to children. Total scores for these adolescents on the children's and adults' Form Y inventories were only moderately correlated. rs between the two sets of factor scores were low. These findings raise the question of whether the Trait Anxiety scale of the children's inventory when completed by adolescents measures the same construct of trait anxiety as the adult inventory. Researchers must evaluate further the validity of the children's inventory Trait Anxiety scale when administered to adolescents.

Adolescent↗

Stroke with negative brain magnetic resonance imaging.

BACKGROUND AND PURPOSE: Magnetic resonance imaging (MRI) of the brain is replacing computed tomography in the diagnostic evaluation of acute ischemic strokes. Past studies have suggested that MRI may not visualize all acute strokes, but few clinical details were included. To better understand the clinical characteristics of strokes not detected by MRI, we collected and reviewed case histories of several patients with acute stroke who had negative MRI scans. METHODS: Patients with a clinical diagnosis of stroke and negative brain MRI scans were ascertained from hospital records dating from 1989 to mid-1991. Patients with transient ischemic attacks, postictal paralysis, functional examinations, central nervous system infections, other nonstroke diagnoses, or equivocal findings were excluded. The MRI scans were performed with a GE Signa 1.5-T magnet in an axial plane (spin-echo repetition time/echo time: 500 msec/20 msec; 2,500 msec, 30 msec/80 msec). One patient received contrast material. RESULTS: We identified seven patients with clinically diagnosed ischemic stroke and negative brain MRI scan. Six of seven patients were scanned within 7 days of symptom onset and two patients within 24 hours. One patient was scanned 3 months after symptom onset. The strokes not detected by MRI were clinically localized to the cortex (n = 3), brain stem (n = 3), and subcortical/lacunar area (n = 1). One patient underwent two MRI scans, one with gadolinium. CONCLUSIONS: These cases, while selected, illustrate some potential limitations of MRI for diagnosing stroke.

Aged↗

Positron emission tomography in neuropsychiatry.

Positron emission tomography (PET) allows high-resolution, three-dimensional evaluation of regional brain metabolic activity and neurotransmitter function. This imaging technique has been applied increasingly in psychiatric research and may yield new information regarding the neural mechanisms of several mental disorders. This article is an overview of PET studies conducted on schizophrenia, affective disorders, and anxiety disorders. Although this research is in the preliminary stage with some inconsistent findings, general trends have emerged that clearly warrant further investigation. These trends are discussed in light of relevant methodological and theoretical issues. Potential directions for future PET research are reviewed.

Anxiety Disorders↗

Brain imaging in dementia of the Alzheimer type.

Neuroimaging modalities have increased understanding of brain abnormalities in dementia of the Alzheimer type (DAT), and is important in assessment of dementia syndromes by revealing focal disorders, demonstrating potentially treatable conditions, and by documenting progression of disease severity. Computed tomography (CT) and magnetic resonance imaging (MRI) have delineated structural changes in DAT, including cerebral atrophy associated with cortical sulci widening and ventricular enlargement, and deep white-matter lesions with periventricular distributions. Positron emission tomography (PET) has demonstrated diminished regional glucose metabolism at parietal and temporal lobes in DAT, while frontal hypometabolism tends to occur in more severe cases. Metabolic dysfunction assessed by PET appears to be the first indication of a degenerative cortical process in DAT, while anatomic changes on CT or MRI may become evident later in the disease process. This selective overview provides an analysis of the current status and future prospects of brain imaging in DAT.

Alzheimer Disease↗

A behavioral perspective on conduct disorders.

THIS paper provides a selective overview of behavioral approaches for conduct-disordered behavior. Although no definitive statement can be made regarding etiology, some empirical support exists for behavioral strategies. Assessment approaches discussed include the behavioral interview, behavioral observations, and behavioral checklists. Decisions regarding types of behavioral interventions to be employed directly follow from assessment data. Assessment information can be formulated in terms of a behavioral excess/skill deficit model. Hence, conduct-disordered behavior can be a function of excessive disruptive behavior and/or a lack of requisite skills necessary to obtain satisfaction. Parental training strategies in contingency management and contingency contracting are discussed regarding behavioral excesses. Relative to skill deficits, contingency procedures along with skills training in communication, problem-solving and self-control are reviewed, using parental training and cognitive-behavioral frameworks. In general, these interventions have empirically demonstrated efficacy. However, future research is required to identify specific factors that account for successful treatment, and attention should be directed toward preventive issues. Important data could be obtained from the identification of high-risk environmental situations. A predictive understanding of high-risk populations could result in the development of early intervention programs, which might to some extent obviate the occurrence of conduct disorders.

Adolescent↗

Psychiatric aspects of AIDS.

Acquired immune deficiency syndrome (AIDS) has neuropsychiatric and psychopathological complications: anxiety, depressive symptoms, and suicidal ideation are common. Patients may express anger toward ineffective medical care and perceived public discrimination, guilt about sexual practices or drug abuse, reactions to social isolation, and uncertainty about the implications of an AIDS diagnosis. CNS dysfunction and subsequent neuropsychiatric impairment are common and are initially characterized by decreased acuity, slowed mentation, and psychomotor retardation that can resemble depression. Marked global cognitive deficits, disorientation, and delusions ensue. The author discusses case management and outlines future clinical and research activities.

Acquired Immunodeficiency Syndrome↗

Topography of human intelligence across race: factorial comparison of black-white WAIS-R profiles for criminal offenders.

Comparison of intellectual functioning across racial groups is an important scientific issue with broad interdisciplinary implications. A large random sample (N = 275) of Black and White incarcerated individuals were studied to evaluate the topography of intelligence across race. Principal factor analyses yielded the general intelligence-g factor along with specific Verbal Comprehension and Perceptual Organization dimensions. All three of these structural components were highly congruent between Whites and Blacks. Theoretical implications of these data include: (1) evidence of qualitatively equivalent intellectual functioning across race, (2) justification of a verbal-performance dichotomy of adult intelligence across racial groups, and (3) support for construct validity of adult intellectual assessment across race.

Adult↗

Cardiovascular reactivity to psychological stress in aerobically trained versus untrained mild hypertensives and normotensives.

Cardiovascular reactivity to video game and mental arithmetic stressors was compared among three groups of men: aerobically trained mild hypertensives, untrained mild hypertensives, and a comparison group of untrained normotensives. Relative to the untrained hypertensives, the trained hypertensives reacted to the video game with marginally smaller systolic blood pressure and diastolic blood pressure, but there were no significant differences between these groups in reactivity during the mental arithmetic task. Comparisons between each hypertensive group and the normotensive group showed that blood pressure (BP) reactivity of normotensives during the video game was generally similar to that of trained hypertensives but smaller than that of untrained hypertensives. These results indicate that aerobic training, which has been found to reduce resting BP in mild hypertensives, may also exert a favorable impact in reducing cardiovascular reactivity of hypertensives during some stressful situations.

Adult↗

Assessment of depression in childhood and adolescence: an evaluation of the Center for Epidemiological Studies Depression Scale for Children (CES-DC).

Psychometric characteristics of the Center for Epidemiological Studies Depression Scale for Children (CES-DC) were evaluated with 148 child and adolescent psychiatric inpatients. Test-retest reliability, internal consistency, and concurrent validity were adequate. Principal components analysis identified three distinct factors: behavioral and cognitive components of depression and a happiness dimension. However, subsequent factor scores and CES-DC total scores were unable to discriminate DSM-III diagnoses, including depressive and nondepressive categories. The CES-DC showed poor reliability and validity in the children alone but had good psychometric properties for the adolescents. More validational research is required before standard clinical use can be recommended.

Adolescent↗

Temporal stability of psychophysiological responding: a comparative analysis of mental and physical stressors.

Although extensive research has been conducted on psychophysiological reactivity, there is a paucity of data concerning the temporal stability of such procedures. Test-retest reliability of experimental stressors from both mental and physical modalities were assessed using a wide range of psychophysiological measures. Absolute baseline and test values demonstrated adequate test-retest reliability for skin temperature, skin resistance, vasomotor response, heart rate, systolic and diastolic blood pressure, while forearm EMG had low reliability. Difference scores, which represent change from baseline to test conditions, did not have adequate reliability. These data represent a necessary step towards standardization of psychophysiological assessment techniques and thus may guide further use of more reliable methods.

Blood Pressure↗

Acquired immune deficiency syndrome: an overview of central nervous system complications and neuropsychological sequelae.

The Acquired Immune Deficiency Syndrome (AIDS) has been associated with a series of central nervous system (CNS) complications, including focal and nonfocal neurological indications. Overall, the most common form of CNS dysfunction is diffuse cerebral atrophy pathologically characterized by neuronal loss, glial nodules, and microfocal demyelination. Consequent neuropsychological deficits present an insidious course initially typified by poor memory and concentration, along with psychomotor retardation and blunted affect which resembles psychological depression. Gradually over several weeks to months, patients exhibit marked global cognitive impairment and can become severely disoriented and delusional. Clinical research relevant to these CNS complications and neuropsychological sequelae are reviewed.

Acquired Immunodeficiency Syndrome↗

Prevalence of DSM-III conduct and adjustment disorders for adolescent psychiatric inpatients.

The prevalence of DSM-III conduct and adjustment disorders in two adolescent psychiatric facilities, both located near large U.S. cities, was investigated. Overall, 31.6% of the adolescent inpatients were conduct disordered while 12.5% were adjustment disordered. The conduct disorders were primarily "aggressive" subtypes suggesting that this characteristic may influence hospitalization and diagnostic decisions. Such data on prevalence assists future treatment planning, allowing anticipation of case loads.

Adjustment Disorders↗

Age differences on alcoholic MMPI scales: a discriminant analysis approach.

Ninety-one male alcoholic inpatients were administered the MMPI after detoxification. Subjects were divided into four age groups. One-way analysis of variance was calculated on the 13 clinical scales and 15 experimental scales (A, R, ES, MT, LB, CA, DY, DO, RE, PR, ST, CN, AT, SO-R, AMAC). In addition, two discriminant analyses were calculated to evaluate whether the inclusion of the 15 experimental scales would increase the percent of correctly classified alcoholics according to age. Results indicated that the Psychopathic Deviant and Paranoia scales declined with increasing age. The Low Back Pain scale indicated a decline from the 50-65 group to the 20-29 group, while the Responsibility scale increased with age. Results from the two discriminant analyses suggested that inclusion of the 15 experimental scales improved the percentage of correctly classified alcoholics.

Adult↗

Blepharospasm: a case study comparison of trihexyphenidyl (Artane) versus EMG biofeedback.

Blepharospasm is a chronic condition characterized by involuntary spasmodic closure of the eyelid(s). The present investigation empirically evaluated the relative efficacies of a current pharmacological and a psychological approach in the treatment of blepharospasm. An A-B-A-C-A single-case design was used to compare trihexyphenidyl [Artane] with EMG biofeedback. EMG activity in the frontalis muscle and number of eyeblinks were the dependent variables. The results indicated that Artane had no effect on either dependent measure and that biofeedback had a dramatic treatment effect on both dependent variables. Treatment gains were maintained at a 42-week follow-up. These results are discussed in light of the methodological considerations, the efficacy of psychological intervention, and the need for future research.

Biofeedback, Psychology↗

Blepharospasm and Meige syndrome: a review of diagnostic, aetiological and treatment approaches.

No known pathophysiological mechanism can explain the majority of cases of blepharospasm, i.e. spasm of the orbicularis oculi muscle; it may also affect the lower face, neck and jaw--Meige syndrome. Only symptomatic treatment is possible, and surgery should be a last resort for severe cases. Much more clinical research will be required before promising behavioural interventions, including biofeedback, can be considered treatments of choice.

Acetylcholine↗