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Biomedical subjects

M E Levin

Publications and source records attributed to M E Levin.

At least 19 recordsLinked to original sources
PubMed1992

Subtractive processes in light adaptation.

We measured the time course of light adaptation in foveal vision following the onset of an adapting background. Several adaptational steps in the low to mid photopic range were examined. The time course of multiplicative and subtractive components of the adaptation were extracted from the data. Unlike previous findings there were no subtractive changes for several hundred milliseconds following light onset, and the process took 10-15 sec to reach steady state. It seems likely that the fast component previously observed results from effectively instantaneous center-surround antagonism, and that our measurements reflect a second subtractive process involving the slow loss of the d.c. signal over time.

Adaptation, Ocular↗
PubMed1987

Understanding your diabetic patient.

In 1987, it is quite evident that the diagnosis etiology, complications, and management of diabetes have come a long way since those days 65 years ago when the lifespan of an insulin-requiring diabetic was 1.2 years. There are exciting times ahead. Today, with the number of diabetics increasing and the problems multiplying, anyone caring for diabetics should have a general knowledge of all aspects of the disease and be able to participate in the total care of the diabetic. For example, the podiatrist should not confine diabetic care only to the foot, but should check blood sugars and blood pressures, take brief diabetic histories, suggest yearly eye examinations, and encourage adherence to diet, blood sugar control, exercise programs, and the avoidance of smoking. While great strides have been made in diabetic management particularly in the last decade, the ultimate cure is yet to be achieved and is the goal of the future.

Adult↗
PubMed1986

Pregnancy and diabetes. Team approach.

Each year, 10,000 babies are born to diabetic women. Gestational diabetes occurs in 2% of all pregnant women, resulting in 60,000 to 90,000 cases of gestational diabetes yearly. Prior to 1922 and the discovery of insulin, fetal mortality for the pregnant diabetic was almost 100%. Today, total fetal mortality for the pregnant and gestational diabetic is approaching that of the nondiabetic. This has been achieved by extremely tight control of blood glucose levels throughout pregnancy, with blood glucose levels averaging under 100 mg/dL/day and glycosylated hemoglobin levels in the normal range throughout pregnancy. An increased number of malformations in fetuses of pregnant diabetic women is still a problem. However, animal and human studies indicate that a normal level of glycosylated hemoglobin at conception may significantly reduce these malformations.

Birth Weight↗
PubMed1978

Effects of hypoglycemic agents on vascular complications in patients with adult-onset diabetes. VII. Mortality and selected nonfatal events with insulin treatment.

The University Group Diabetes Program is a long-term prospective clinical trial designed to evaluate the effects of various hypoglycemic agents on vascular complications in patients with asymptomatic adult-onset diabetes. Mortality and blood glucose levels were determined as well as certain nonfatal events for patients assigned to diet alone or to either of two insulin treatment regimens. Lower levels of blood glucose with mean values close to normoglycemia were achieved in the treatment group in which the insulin dosage was adjusted to achieve normoglycemia compared with the levels achieved in patients treated with diet alone or with a fixed dose of insulin. In spite of differences in blood glucose levels among the treatment groups, there were only minor differences in the occurrence of fatal or nonfatal events.

Blood Glucose↗
PubMed1976

Effects of diabetes mellitus on bone mass in juvenile and adult-onset diabetes.

To assess the influence of diabetes mellitus on bone metabolism, we measured skeletal mass in the forearms of 35 patients with juvenile diabetes on insulin and 101 stable patients with adult-onset diabetes, on diet alone, insulin, or oral hypoglycemic agents. There was a significant loss of bone mass in both juvenile and adult-onset diabetes (P less than 0.01) as compared to controls matched for age and sex. The decrease was already present in patients with diabetes of less than five years' duration. Bone loss and duration of the diabetes did not correlate; the greatest decrease in bone mass was observed in the patients receiving oral agents. These data are consistent with the hypothesis that the loss of skeletal tissue in diabetes reflects the underlying disease since it occurs early and is not related to severity as evidenced by the need for insulin, to duration, or to treatment with insulin or diet alone.

Adult↗
PubMed1976

The diabetic foot.

Explore the source record for details and available documents.

Amputation, Surgical↗