B-cell markers on lymphoblasts in acute lymphoblastic leukaemia.
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Biomedical subjects
Publications and source records attributed to M E Nesbit.
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Five of nine children with acute lymphoblastic leukemia had lymphoblasts that bound sheep erythrocytes or reacted with antiserum to thymocytes, suggesting involvement of T (thymus-derived) cells. When lymphoblasts from all patients were examined by immunofluorescence they were found to lack a marker for B (bone marrow or bursa-equivalent) cells, that is, the presence of surface immunoglobulins.
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