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Biomedical subjects

M E Nichitaĭlo

Publications and source records attributed to M E Nichitaĭlo.

At least 19 recordsLinked to original sources

[The prognosis of postoperative complications in patients with bile duct obstruction of a nontumorous origin].

The computer analysis of treatment results of 113 patients with biliary ducts nonneoplastic impassibility was conducted. One instrumental and five clinico-laboratory mostly informative prognosing features were picked out concerning the origin of septic-purulent complications. Discriminant analysis method application permitted to prognosticate the complications in 76% of observations and elaborate the tactics of patients treatment.

Cholestasis

[Diagnosis of cancer of the pancreatic body and tail].

Results of 194 patients observation with cancer of corpus et cauda pancreatis are adduced. Clinical forms of the disease are distinguished. Rational algorithm for the examination of patients with probable cancer of corpus et cauda pancreatis diagnosis was elaborated grounded on the efficacy analysis of various methods of examination (ultrasonic investigation, computed tomography, endoscopic retrograde cholangiopancreatography, selective, angiography and so on). The algorithm application permitted to improve significantly the diagnosis of disease.

Adult

[Surgical treatment of nonparasitic cysts of the liver].

The authors have observed 218 patients with nonparasitogenic cyst of the liver. Of them 94 were operated on. The cyst enucleation, partial excision of its wall, external cyst drainage, cystodigestive anastomosis formation, combined liver and the cyst resection were done. Preference to the cyst enucleation (in 22.5% of observations), its partial excision (in 33.8%) and combined resection of liver with the cyst (in 19.4%) was given. In polycystosis the partial excision of large cysts were the alternative operations as well as omento-hepatopexy. One (1.06%) patient have died. Postoperative complication occurred in 23 (24.2%) of patients.

Adolescent

[Experimental-clinical substantiation of the use of atraumatic suture material "metallatravm" in the surgery of bile ducts].

High efficacy of home sutural material "Metallatravm" application while biliary anastomoses creation was proved in experiment on 180 white rats. One-layer extramucosal interrupted suture application proved as a long-term one. In 35 patients with biliary ducts obstruction high efficacy of applied material was noted. Ligature cholelithiasis and stenosis recurrences were not observed.

Anastomosis, Surgical

[Diagnosis and surgical treatment of tubular stenosis of the distal common bile duct].

The results of operative treatment of 90 patients with tubular stenosis of common biliary duct distal portion of nonneoplastic genesis were analyzed. The scheme-algorithm of the patients examination and differentiated approach to the operative procedure choice at the various tubular stenosis forms were proposed. Late follow-up results of treatment were achieved due to application, when indicated, of operation on major duodenal papilla, and also the direct draining and resecting interventions on pancreas. The mortality was 2.2%.

Adult

[Regional immunocorrective therapy using laferon in patients with suppurative cholangitis].

In patients with purulent cholangitis after correction of major bile outflow, intracholedochal administration of laferon was used together with general and antibacterial therapy. This contributed to improvement in the function of a cellular link of immunity, decrease in intensity of autoimmune response of the own lymphocytes, stabilization of general inflammatory response of the organism which resulted in normalization of pathologically increased laboratory and biochemical indices in the blood analyses of the patients.

Cholangitis

[Rationale for surgical treatment of focal liver diseases].

A 19-year experience with surgical treatment of the patients with focal hepatic lesions is presented. Hepatic resection was performed in 149 patients. Of them, 52 underwent atypical resection with the use of ultrasound aspirator, laser scalpel, temporary exclusion of the liver out of circulation, placement of staple suture of the parenchyma, preliminary roentgenovascular embolization of the major vessels of the lobe removed. A modern classification of the methods of hepatic resection reflecting most accurately a volume of the parenchyma removed is presented. The postoperative lethality was 6.08%.

Extracorporeal Circulation

[A rational procedure for the treatment of patients with chronic calculous cholecystitis complicated by choledocholithiasis].

The results of surgical treatment of 156 patients with chronic calculous cholecystitis complicated by choledocholithiasis have been analysed. In 62 patients, cholecystectomy in combination with choledocholithotomy was performed. Ninety four patients underwent additional drainage operations on the terminal common bile duct. Endoscopic papillosphincterotomy was performed in 90% of cases, other drainage interventions (choledochoduodenostomy and transduodenal papillosphincterotomy)--in 10%.

Cholecystectomy

[The differential diagnosis and therapeutic procedure in nontumorous mechanical jaundice and cholangitis].

The results of operative treatment of 2,875 patients with obstructive jaundice and cholangitis of nonneoplastic genesis are generalized. On the basis of rich clinical experience, the authors substantiate the principles of differential and topical diagnosis in obstructive jaundice and purulent cholangitis as well as the optimal therapeutic tactics in obstruction of the bile ducts of various levels and types. Problems are elaborated with respect of complex antibacterial therapy with the use of various routes of administration, including administration in the pre- and intraoperative period for preventive purposes.

Cholangitis

[Endovascular regional infusion therapy in the combined treatment of liver abscess].

The comparative assessment of the effectiveness of endovascular regional infusion therapy (ERIT) in the complex of treatment of a hepatic abscess in 16 patients was carried out. In 12 patients, it was performed in combination with surgical intervention, in 4--as an independent method of treatment. In patients with a solitary hepatic abscess, it is expedient to include ERIT into the complex of therapeutic measures in combination with abscess puncture under ultrasound guidance. In presence of multiple abscesses of the liver, ERIT is a method of choice.

Adolescent