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M E Price

Publications and source records attributed to M E Price.

11 recordsLinked to original sources
PubMed1991

Structure of an unusually non-polar hydroxy ether.

(1R*,3R*,7S*,9S*)-1,4,4-Trimethyl-9-(tert-butyldimethylsilyloxy)-e xo-11-oxatricyclo[5.3.1.0(2,6)]-undecan-3-ol, C19H36O3Si, Mr = 340.90, orthorhombic, Pbca, a = 10.411 (3), b = 13.275 (3), c = 29.085 (10) A, V = 4019 (2) A3, Z = 8, Dx (130 K) = 1.13 g cm-3, lambda(Mo K alpha) = 0.71069 A, mu = 1.24 cm-1, F(000) = 1504, T = 130 K, R = 0.077 for 1005 observed reflections with I greater than 3 sigma(I). The compound, whose connectivity was not readily apparent from spectroscopic and chemical information alone, possesses a tricyclic framework containing an O-bridged bicyclo[3.2.1]octane fused in a cis-exo manner to a cyclopentanol ring. Most noteworthy is the considerably lower polarity of this compound relative to its opposite cyclopentanol stereoisomer. The close proximity [2.78 (1) A] of the bridging O atom in the [3.2.1] system to the hydroxyl O atom on the five-membered ring is suggestive of an intramolecular hydrogen bond, although the H atom could not be located.

Bridged-Ring Compounds↗
PubMed1990

Rational selective exploitation and distress: employee reactions to performance-based and mobility-based reward allocations.

Prior research has demonstrated that allocators frequently distribute greater rewards to persons with high professional and geographic mobility than to persons with constrained mobility, especially among the very competent. This phenomenon has been termed rational selective exploitation. Do the recipients of such allocations actually experience this distribution rule as unjust and distressing, or is it a misnomer to refer to this phenomenon as exploitation? Two studies were conducted to explore this question. Study 1 was a laboratory experiment in which we manipulated relative performance level, relative mobility level, and allocation standard: performance based versus mobility based. Study 2 was a cross-sectional survey of actual employees in which subjects reported the degree to which performance and mobility were the basis for pay decisions at their places of employment, as well as the degree to which they perceived each standard to be fair. Both studies demonstrated that people regard mobility-based allocations as less fair and more distressing than performance-based allocations. Furthermore, the degree of distress resulting from mobility-based allocations is greater among persons who are disadvantaged by that standard: among people with constrained mobility, especially those who perform at high levels. These findings provide good support for the assertion that so-called rational selective exploitation is indeed distressing to employees. Reactions to this form of distress are also explored, and the implications of these findings for the allocation process are discussed.

Adaptation, Psychological↗
PubMed1988

A prospective study of maternal and fetal outcome in acute Lassa fever infection during pregnancy.

Several viral infections have been reported to result in more severe disease in pregnant than non-pregnant women, but the relative risks have not been well characterised. This has now been done for Lassa fever in a prospective study of 68 pregnant and 79 non-pregnant women who were admitted to hospital in Sierra Leone with confirmed Lassa fever. Lassa fever was the main cause of maternal mortality in the hospital, accounting for 25% of maternal deaths. Twelve of 40 patients in the third trimester died, compared with two of 28 in the first two trimesters and 10 of 79 non-pregnant women. The odds ratio for death in the third trimester compared with the first two trimesters was 5.57 (95% confidence intervals 1.02 to 30.26). The condition of the mother improved rapidly after evacuation of the uterus, whether by spontaneous abortion, evacuation of retained products of conception, or normal delivery; 10 of 26 women without uterine evacuation died, but only four of 39 women with evacuation died (p = 0.0016). The odds ratio for death with pregnancy intact was 5.47 (95% confidence interval 1.35 to 22.16). Fetal and neonatal loss was 87%. The risk of death from Lassa fever in the third trimester is significantly higher than that in the first two trimesters and higher than that for non-pregnant women, but evacuation of the uterus can significantly improve the mother's chance of survival.

Acute Disease↗