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Biomedical subjects

M E Rylance

Publications and source records attributed to M E Rylance.

3 recordsLinked to original sources

Patients' attitudes following chorionic villus sampling.

The attitudes of 190 patients who had undergone chorionic villus sampling (CVS) were assessed by means of a questionnaire. One hundred and fifty-two patients replied of whom 68 (45 per cent) were referred because of increased maternal age and in the other 84 cases the indications included previous chromosomal abnormalities, fetal sexing, DNA analysis, and biochemical analysis. One hundred and twenty-two patients had a transcervical procedure, 24 had a transabdominal, and six patients required both procedures. One hundred and forty-one patients (93 per cent) reported CVS to be a satisfactory procedure, and the same percentage thought earlier diagnosis was beneficial. Thirty-nine patients (81 per cent) reported a better experience with CVS than with a previous amniocentesis. A majority of patients (93 per cent) wished a CVS in a future pregnancy and 137 patients (97 per cent) would accept a risk of miscarriage from the procedure of twice that quoted for amniocentesis (1 per cent).

Attitude↗

Use of drugs by children.

To obtain information on the use of prescribed and non-prescribed drugs in the general population of children 1590 children were surveyed in 1984-5 by weekly questionnaires filled out by parents. Drugs were taken in 13% of the 26 weeks studied and on 9% of the 182 days. Use in the summer and winter was similar. More than half (56%) of all drugs were taken on Saturdays and Sundays. Boys took drugs on 11% of days and girls on 8% of days. Almost half (45%) of drugs taken were not prescribed. Drugs acting on the respiratory tract and on coughs accounted for 42.2% of the drugs used. Analgesics were taken on 14.0% of days and antimicrobials on 12.5%. Aspirin accounted for 14.9% of all drugs used in any one week and for 31.7% of drugs obtained without prescription. Aspirin, paracetamol, triprolidine-pseudoephedrine (Actifed), ampicillin or amoxycillin, and salbutamol were the drugs most frequently used. The widespread use of drugs obtained without prescription suggests that community pharmacists and parents would benefit from further education on the choice of treatment in relation to symptoms. Doctors should be aware of the extent of treatment with non-prescription drugs and consider playing a greater part in advising on its indications.

Adolescent↗