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Biomedical subjects

M E Sitdykova

Publications and source records attributed to M E Sitdykova.

11 recordsLinked to original sources

[Iatrogenesis in urology].

The proportion of misdiagnosis and errors in the treatment of urological diseases holds high, this being particularly true for iatrogenic pathology of the ureter and urinary bladder. The disturbances used to arise in response to traumatic gynecological and proctological surgical interventions and often remained undetected. The traumas are mainly induced by inaccurate use of the instruments and defects in surgical techniques. One of the serious iatrogenic complications is microcystic involvement of the urinary bladder as a result of radiotherapy for cancer. The method proposed by the authors for medical and social rehabilitation of such patients implies the replacement of the affected urinary bladder with isolated intestinal segment providing the recovery of natural uresis. Systemic endotoxinemia, another variant of urologic iatrogenesis, is associated with massive-dose antibiotics and extensive intracavitary operations. Early diagnosis and management of the conditions are supposed an effective protection against endotoxin shock.

Diagnostic Errors↗

[Replacement of the bladder with isolated intestinal loop].

Based on the experience with 98 operations performed for replacement of the urinary bladder with an isolated intestinal segment, it was demonstrated that the most frequent complications were peritonitis, inflammation of the lung that develop mainly with the postoperative paresis of the digestive tract in the background. Therefore, a complex of prophylactic and therapeutic measures for the postoperative intestinal paresis is recommended, the technic of surgical intervention being described in detail. A comparison of the results of surgery, taking into account the mode of the urine outflow in cystectomy, enabled to consider cystectomy with replacement of the bladder with an intestinal graft as the method of choice.

Adolescent↗

[Choice of a method of surgical treatment of urinary bladder neoplasms].

The results of treatment of 850 patients with urinary bladder cancer (UBC) are analysed. Precise staging of the tumor should be made in the following order: suprapubic ultrasonic investigation (USI), cystoscopy and microcystoscopy, transrectal, transurethral USI. Indications for different treatments are outlined: typical and atypical papillary fibroepithelioma, papillary cancer in stage T1 should be managed with TUR after previous electrocoagulation; cancer in stage T2-3--with urinary bladder resection and uni- or bilateral pelvic lymphadenectomy; total papillomatosis, multiple lesions in stage T3, in cases of recurrent cancer--with cystectomy including one-stage or multistage replacement of the urinary bladder by intestinal transplant. The only physiologically sound method of treating patients after cystectomy with ureterocutaneostomy and ureterocolostomy is creation of intraperitoneal intestinal urinary bladder with reestablishment of transurethral urination. Arguments against creation of artificial urinary bladder made of detubularized segments consist in the absence of advantages.

Cystectomy↗

[Patient rehabilitation following cystectomy for cancer].

In 171 out of 251 cancer patients subjected to cystectomy, the bladder was replaced for isolated intestinal segment followed by recovery of transurethral urination. This recovery produced a favorable effect on physical, psychological and social, occupational status of the patients. Two-stage technique of establishing reservoir for the urine with renewal of transurethral urination is detailed. Normalization of the function of the kidneys and upper urinary tracts, prevention or early treatment of complications, natural transurethral urination should be considered criteria for rehabilitation of postcystectomy cancer patients.

Adult↗

[Efficacy of a plant complex Prolit after extracorporeal lithotripsy in patients with urolithiasis].

A study of an additive prolit efficacy was made in the urological clinic of Kazan State Medical University. All the examinees were divided into two groups: 20 patients of group 1 were exposed to extracorporeal lithotripsy (EL) followed by conventional postoperative conservative therapy, 22 patients of group 2 received EL plus prolit. The latter was able to reduce twice the time of concrement elimination from the urinary tract after EL, to lower leukocyturia from 86.4 to 18% and bacteriuria from 50 to 13.6%, renal colic rate and risk of stone path after EL, to improve renal blood flow and to reduce the risk of traumatic parenchymal damage due to the shock wave impact in EL.

Adolescent↗

[The formation of an artificial bladder from the intestines].

Basing on the long-term experience in radical surgery of 252 patients with invasive bladder cancer, the authors come to the conclusion that the establishment of intestinal bladder with postcystectomy recovery of physiological uresis is the most proper therapeutic approach. Extra- or intraperitoneal position of the transplant was decided upon regarding the type and stage of cystectomy and prior methods of derivation. The techniques of one- and multistage operations are presented. Clinical practice evidences that more rapid recovery of urethral uresis can be obtained with application of primary continuous suture of artificial intestinal bladder (ideal enterocystoplasty) at the end of the surgery. Urodynamic low urinary tract findings are provided. The technique developed by the authors offers new surgical opportunity for bladder cancer patients following cystectomy.

Cystectomy↗