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Biomedical subjects

M E Stuart-Taylor

Publications and source records attributed to M E Stuart-Taylor.

6 recordsLinked to original sources

Calculation of drug dosage and body surface area of children.

The British National Formulary and many reference textbooks recommend that drug dosages for children be calculated according to body surface area (BSA). Although many rules for drug dosage have been developed, based on age, weight and surface area, none has been accurate and simple enough for routine use. These rules are described, and one for clinical use: up to 30 kg, a child's drug dose may be (wt x 2)% of an adult dose; over 30 kg, (wt + 30)% of an adult dose. If this percentage of an "adult" dose of a drug is used, not only is the BSA curve followed more closely than with the conventional mg kg-1 regimen, but fewer major errors of prescription may be expected.

Adolescent↗

Why do anaesthetists need codes?

With the increasing availability of information technology in hospitals and the introduction of medical audit and resource management, there is a proliferation of anaesthetic data collection systems. The amount of data recorded varies from a complete anaesthetic record to a small subset of it. Most systems hold data in coded form for reasons of accuracy and compactness. Unfortunately, all the coding systems are different, making comparisons between different centres difficult. We propose that there is a need to develop a standard national system for coding anaesthetic terms.

Anesthesiology↗

Extradural diamorphine for postoperative analgesia: audit of a nurse-administered service to 800 patients in a district general hospital.

We report the use of extradural diamorphine for postoperative analgesia as a nurse-based service on selected surgical wards in a district general hospital. Eight hundred patients received lumbar or thoracic extradural diamorphine analgesia for postoperative or traumatic pain. Diamorphine was administered in bolus form by suitably trained nursing staff. Satisfactory analgesia, recorded on a verbal rating scale at the conclusion of the service, was achieved in 94.6% of patients. The technique was considered by medical and nursing staff to be a safe and acceptable method of analgesia. Respiratory depression, defined as a ventilatory frequency of less than 10 b.p.m., occurred in seven patients (incidence of 0.9%). All occurred in the theatre recovery area or in the intensive care unit. Retrospectively, each was predictable and all responded to naloxone 0.4 mg.

Adolescent↗

A plea for noradrenaline.

Hypotension induced by nifedipine and chlorpromazine is discussed, together with the role of noradrenaline in the correction of this problem, which was resistant to other forms of therapy.

Chlorpromazine↗

Alfentanil infusions. Comparison of bolus administration of fentanyl with three alfentanil infusion regimens.

Three different dosage regimens of alfentanil were compared with boluses of fentanyl in 80 patients who underwent a variety of surgical procedures. Alfentanil given by infusion at a rate of 7.5 micrograms/kg/minute for 10 minutes followed by 0.75 micrograms/kg/minute, was shown to provide a stable anesthetic which minimises the use of a volatile agent for surgery that lasts more than 45 minutes.

Adolescent↗