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Biomedical subjects

M E Wong

Publications and source records attributed to M E Wong.

5 recordsLinked to original sources
PubMed1996

Integrated processes responsible for soft tissue healing.

Wounded soft tissues undergo repair through a complex series of interrelated events that involve both physical and chemical activities. These processes are currently undergoing extensive investigation as efforts are directed toward achieving augmented and accelerated healing. Early wound-healing research focused on expanding traditional histologic descriptions of tissue healing by attempting to characterize the environment and biologic mediators responsible for healing. These initial studies successfully identified a number of agents and physiochemical factors present in healing wounds, but their precise roles and importance remain largely unknown. This review article summarizes the current literature on soft tissue healing. An effort has been made to correlate the activities of the major growth factors and cytokines with the individual reparative processes including the inflammatory response, hemostasis, fibroplasia, angiogenesis, and remodeling. Explanations and characteristics of growth factor function as well as brief descriptions of several major factors and their spectrum of activity are also provided.

Blood Coagulation↗
PubMed1996

The integrated processes of hard tissue regeneration with special emphasis on fracture healing.

When bone is fractured, a sequence of dynamic events ensue to restore form and therefore function. Many key biologic cell regulators for these events have been identified, expressed through recombinant technology, and their roles posited. Moreover, the availability of recombinantly engineered molecules, such as the bone morphogenetic proteins with their potential to benefit patient care, has ushered in an important era in clinical dentistry that may eliminate either autografting or bank bone allografts. Therefore, in this review article, we have highlighted some of the exciting biologic regulators relevant to bone fracture healing and outlined the dynamic elements in this process.

Animals↗
PubMed1988

Meige syndrome: an unusual cause of involuntary facial movements.

Dental and allied health professionals are on occasion confronted with patients who exhibit abnormal facial movements. These patients may be seeking a diagnosis or may relate a specific problem resulting from the uncontrolled and involuntary orofacial movements. A complete description of the various conditions associated with abnormal facial movements is beyond the scope of this article. Instead, these authors present a case with dental symptoms that were masking a more serious underlying progressive neurologic disorder. Appropriate referral to the neurology service is essential so that treatment of the underlying cause may precede, rather than follow, empiric management of these patients' symptoms.

Basal Ganglia Diseases↗
PubMedDate not supplied

Clear cell variant of calcifying epithelial odontogenic tumor: case report and review of the literature.

The calcifying epithelial odontogenic tumor (CEOT) is a rare benign odontogenic neoplasm which was first described by Pindborg in 1955 and accounts for less than 1% of all odontogenic lesions. Recently, a clear cell variant of CEOT has been identified with only eight well-documented cases in the literature. We present an additional case of clear cell CEOT of the mandible and review the salient clinical, radiologic, and histopathologic features of this entity and CEOTs in general. The differential diagnosis of clear cell tumors in the mandible includes: clear cell odontogenic tumor, clear cell ameloblastoma (odontogenic carcinoma), metastatic clear cell adenocarcinoma, primary intraosseous mucoepidermoid carcinoma, acinic cell carcinoma, epithelial-myoepithelial carcinoma, clear cell salivary gland tumors, and clear cell variant of squamous cell carcinoma. Because of the belief that clear cell odontogenic tumors are locally aggressive neoplasms, definitive resection of the entire mass with tumor-free surgical margins and long-term follow-up are recommended.

Diagnosis, Differential↗