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Biomedical subjects

M Edwards

Publications and source records attributed to M Edwards.

At least 253 records · Page 14Linked to original sources
PubMed1981

The design of an accident investigation procedure.

In August 1980, a joint meeting of the IEA and the NES was held in Oslo to discuss "Ergonomics in Action - From Theory to Practice" and papers were invited to illustrate this theme. It is the burden of this paper that ergonomics is not widely practised partly because the model of application implied in the conference theme is inappropriate and partly because ergonomists tend to be laboratory-rather than problem-centered. Some of the constraints associated with problem-centered research in organisations are discussed and a particular problem of applied ergonomics, as it relates to the design of accident investigation procedures, is described.

Journal Article↗
PubMed1980

Intermittent pressure cuffing for oedematous digits.

A double-walled rubber cylinder, made of cheap, readily available materials, is described. This device enables intermittent positive pressure to be applied to individual fingers during the course of management of post-surgical or post-traumatic finger oedema. It has a number of advantages over the standard total hand splint currently used.

Edema↗
PubMed1978

The ability of smooth and rough strains of Streptococcus pneumoniae to activate human complement by the alternative pathway.

Three capsulate pneumococcal strains of serotypes 1, 2 ans 3, and one non-capsulate strain of serotype 47, were found to activate human complement by the alternative pathway to a similar extent over the concentration range examined. Nevertheless, the capsulate strains, in contrast to the non-capsulate, are known to require complement attachment for phagocytosis and it is therefore postulated that the toxic by-products released cause the wave of oedema characteristic of pneumococcal lobar pneumonia.

Bacteriological Techniques↗
PubMed1976

Metabolism As a Function of Water Potential in Air-Dry Seeds of Charlock (Sinapis arvensis L.).

A new method is described for studying the metabolism of air-dry seeds. An initial pulse of (14)CO(2) was supplied to seeds maintained in air at controlled low water potentials for 6 months. Seeds were also infiltrated with 2-(14)C-acetate and with (14)C-l-leucine at 0 C, redried rapidly at 0 C, and maintained at controlled low water potentials for 4 to 6 weeks. The metabolism of the air-dry seeds was a function of the water content of the tissues, which was in equilibrium with the water potential at the seed surface. The fixation of (14)CO(2) and the utilization of 2-(14)C-acetate increased exponentially with water content. The incorporation of (14)C-l-leucine into protein increased linearly with water content. Metabolism was not reduced to a low rate except in air-dry seeds at the lowest water potentials (-1716 to -762 bars) with 4 to 6% water.

Journal Article↗
PubMed1976

Dormancy in Seeds of Charlock (Sinapis arvensis L.): Early Effects of Gibberellic Acid on the Synthesis of Amino Acids and Proteins.

Charlock (Sinapis arvensis L.) seeds were imbibed with 10 mm GA(3) for 24 hours at 0 C. After equilibration at 25 C, a 5-fold increase in radioactivity in the amino acids labeled from 2-(14)C-acetate was observed within 2 hours. The total amount of amino acids was reduced to half, and the specific radioactivity increased approximately 10-fold, indicating a diversion of metabolites for amino acid and protein synthesis in GA(3)-treated seeds. The rate of incorporation of l-(14) C-leucine into protein was doubled. Autoradiographs showed that enhancement of protein synthesis was localized in the shoot and root meristems, the developing vascular tissues, and in the endosperm cells inside the testa.

Journal Article↗