PubMed Health⌕ Search

Biomedical subjects

M Eliakim

Publications and source records attributed to M Eliakim.

At least 91 records · Page 5Linked to original sources
PubMed1977

Thrombocytosis in rheumatoid arthritis. Recurrent arterial thromboembolism and death.

A patient with rheumatoid arthritis complicated by excessive thrombocytosis and recurrent thromboembolic events is presented. The platelet count correlated well with disease activity and thrombosis occurred when thrombocytosis was marked. The patient died from massive thrombosis of the aorta despite treatment with anticoagulants, corticosteroids, and azathioprine.

Adult↗
PubMed1977

Nephrotic syndrome associated with amyloid-like glomerular deposits.

An Arab patient with a typical nephrotic syndrome associated with the deposition of an amyloid-like material in the glomeruli is described. The deposits consisted of an electron-dense finely granular material which contained immunoglobulins and complement and fibrillar structures which resembled those of amyloid but did not stain with the typical amyloid stains.

Amyloidosis↗
PubMed1977

Drug utilization and adverse drug reactions in medical patients: comparison of two periods, 1969--72 and 1973--76.

A study of drug usage and adverse drug reactions was carried out on 2,771 hospitalized medical patients during 1969--76. Comparison of data between 1969--72 and 1973--76 shows an 11% reduction in the average number of drugs per patient, and a 59% decrease in the incidence of adverse effects, calculated as percent of all exposures. The number of patients affected by adverse reactions during the second period fell by 61%. These data seem to indicate that there was considerable improvement in habits of drug usage in the monitored ward.

Adult↗
PubMed1977

A comparative study of hepatitis B and non-B in hospitalized adults in an endemic area.

The epidemiologic, clinical and laboratory features of 40 adults with acute viral hepatitis type B were compared with those of 40 adults with hepatitis non-B. Overall, the clinical presentations were remarkably similar and the etiology could not be determined in individual cases. An exception to this was that all post-transfusion cases in this series were affected by hepatitis B. Men predominated in both the hepatitis B and non-B groups. There was a tendency to seasonal clustering in summer/autumn in both groups. Hepatitis B patients were significantly older and 59% of them had a history of possible parenteral exposure during the six months preceding admission. On the other hand 76% of patients with hepatitis non-B had no apparent parenteral exposure. Dental treatment, injections and contact with jaundiced patients were recorded in both groups and were therefore of no value in determining the exact etiology in individual cases. Fever was more common in hepatitis non-B, while the onset of the disease was insidious and afebrile in 80% of patients with hepatitis B. As a group, patients with hepatitis B had more extensive liver injury and a more prolonged clinical course, and the only fatality was in this group. Cholestatic features were rare and extrahepatic immune complex disease was extremely uncommon in both hepatitis B and non-B.

Adult↗
PubMed1977

Analysis of the work of nurse-practitioners in family practice and its effect on the physicians' activities.

A three-year study on the inclusion of nurse-practitioners (18 months basic training) in family medicine is presented. The nurses were entitled to screen patients and to treat minor ailments. Patient-nurse contact rates were 6.1, 7.1, and 4.2 per year in 1971, 1972, and 1973, respectively. The increased responsibility given the nurses resulted in a decrease in patient-physician contacts from 4.0 in 1970 to 2.0, 2.1, and 1.3 in 1971, 1972, and 1973, respectively. This permitted the physicians to spend more time with each patient, to look for disease in the community, to participate actively in the work of the department of medicine in the regional hospital, and to engage actively in research. As a result, numerous surveys have been performed and a great amount of important medical and epidemiological information has been accumulated. More than one third of all patients handled by nurses suffered from respiratory infections; these were followed by musculoskeletal disorders and skin infections. Diagnosis and treatment accounted for 50 to 53 percent of the nurses' activities. Consequently, the medical and social status of the nurses rose markedly and patients seems to rely increasingly on their judgment.

Acute Disease↗
PubMed1976

Excretion of liver antigens in the urine of patients with hepatic diseases.

Liver antigens were detected in the urine of 4 of 42 patients with various liver diseases. The urine of 25 healthy subjects and patients with diseases not affecting the liver was devoid of antigens in detectable amounts. The presence of hepatic antigens in the urine did not correlate with severity of jaundice and SGOT levels but correlated with parenchymal necrosis and was associtated with a high mortaltiy.

Adult↗
PubMed1976

Type B and non-B viral hepatitis in Jerusalem.

In a two-year survey of adult patients hospitalized with acute viral hepatitis in Jerusalem, 27% were reactive for the hepatitis B surface antigen (HB(s)Ag) by radioimmunoassay and therefore diagnosed as having hepatitis B. The majority of patients (73%) were non-reactive for HB(s)Ag and their diagnosis was non-B hepatitis ("type unspecifiable"). Thirty-one per cent of patients with hepatitis B and only 5% of patients with non-B hepatitis had histories consistent with parenteral transmission of hepatitis by blood transfusion or drug use. An additional 19% of the patients with hepatitis B had possible parenteral exposure and 50% had no obvious parenteral exposure, indicating that non-parenteral transmission of the hepatitis B virus (HBV) may be a significant epidemiological factor (50-69%) in the Jerusalem area. The prominent role of non-parenteral transmission of HBV is further evidenced by the relatively high prevalences of HB(s)Ag (0.97%) and antibody to hepatitis B surface antigen (anti-HB(s)) (19.0%) in healthy blood donors. These findings are consistent with the view that personal contact and intra-familial spread may be important factors in the epidemiology of HBV and indicate that non-parenterally transmitted HBV contributes significantly to endemic viral hepatitis in the Jerusalem area.

Acute Disease↗
PubMed1975

Latrogenic lipidosis following prolonged intravenous hyperalimentation.

Intralipid was used as the main source of calories in the long-term therapy of a patient with severe nutritional failure and cachexia. The treatment was tolerated well for 64 days. The patient died of sepsis after a second therapeutic course which lasted 16 days adn was preceded by an impairment in liver function apparently related to starvation. At autopsy, free fat droplets and extreme foamy swelling of the cytoplasm of the reticuloendothelial cells were found in all examined organs. These findings constitute an unusual example of iatrogenic lipidosis. It is suggested that caution be exerted in the administration of Intralipid to patients with impaired liver function and that serum lipids be maintained regularly during therapy.

Adult↗
PubMed1975

Acute idiopathic pericarditis in the aged.

Eleven elderly patients with idiopathic pericarditis are reported. All but one were older than 60 yr. Evidence of ischemic cardiovascular disease was present in 8 patients. The initial diagnosis was heart failure with pulmonary complications in 4 cases and myocardial infarction in 3. Respiratory infection preceded the onset of pericarditis in 5 cases. Presenting symptoms were typical precordial pain, fever and dyspnea. Pericardial friction was found in 7 cases and transient rhythm disturbances in 5. Four patients had ST elevation and 3 had ST depression in their electrocardiograms. Other findings included an increased sedimentation rate, leukocytosis, elevated venous pressure and normal SGOT levels. Antibiotics were of no avail but prednisone had a dramatic effect. Two patients had a relapsing course lasting 2 yr or more. One patient, who died at the age of 75 from bleeding ulcer, had patent coronary arteries and mild perimyocardial fibrosis. The diagnosis of idiopathic pericarditis in the aged is difficult because the disease simulates ischemic heart disease in patients who frequently have evidence of arteriosclerotic cardiovascular involvment.

Acute Disease↗
PubMed1975

Obstructive jaundice associated with carcinoma of the prostate.

An unusual case of prostatic carcinoma presenting as severe obstructive jaundice is reported. After treatment with stilbestrol and bilateral orchidectomy, liver function tests became normal and lung metastases disappeared. During a second episode of jaundice due to serum hepatitis, liver function deteriorated following stilbestrol administration, and the drug was temporarily discontinued. The patient has been followed up for three years and liver function tests remain normal.

Adenocarcinoma↗
PubMed1975

Antimicrobial therapy in patients hospitalized in a medical ward. A report from the Boston Collaborative Drug Surveillance Program.

The pattern of use of antimicrobial agents in 1,700 patients hospitalized in a medical ward at the Hadassah University Hospital, Jerusalem, during 1969--72, is analyzed. Penicillins comprised 56%, tetracyclines 11%, streptomycin 9% and cephalosporins 3% of the total antimicrobial exposures. Ampicillin was given to 20% of the patient population. The use of tetracyclines and chloramphenicol fell steadily from 1969 to 1972. Fifty-five percent of the recipients of antimicrobial drugs received only one agent, 19% had concomitant therapy with several agents and the remainder received multiple antimicrobial drugs sequentially. One hundred and ten patients (6.5%) developed adverse reactions; the most common being rash and gastrointestinal reactions. Only two of the reactions were classified as causing major morbidity.

Ampicillin↗